Clinical trials: Autonomic Dysreflexia
Spinal Cord Injuries, Autonomic Dysreflexia
Autonomic Dysreflexia in Spinal Cord Injuries: UDS Filling Speed Impact
In patients with spinal cord injury, the investigators want to understand and understand the differences in AD prevalence and characteristics according to bladder injection rate, and to determine which factors have a greater…
- Conditions
- Spinal Cord Injuries, Autonomic Dysreflexia, UDS Filling Speed
- Trial name
- NCT06211491
- Testing
- Urodynamic test
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Pusan National University Yangsan Hospital
Spinal Cord Injuries
Acute Effects of Continuous Verses Interval Aerobic Training in Spinal Cord Injury Patient
To determine the Acute effects of continuous verses interval aerobic training on autonomic dysreflexia in Spinal Cord injury Patient. To Determine the Acute effects of these training on, Exercise Self efficacy and pain.
- Trial name
- NCT05061160
- Testing
- Interval Aerobic Exercise training Group, Continuous Aerobic Exercise training Group
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Multiple Sclerosis, Control Subjects
Deciphering Preserved Autonomic Function After Multiple Sclerosis
This study looks to characterize gradients of dysfunction in the autonomic nervous system in patients with clinically diagnosed multiple sclerosis.
- Conditions
- Multiple Sclerosis, Control Subjects, Autonomic Dysreflexia
- Trial name
- DPAF-MS (NCT07012135)
- Testing
- Tests of sympathetic inhibition, Tests of sympathetic activation, Testing of autonomic dysreflexia
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spinal Cord Injury
Cardiovascular, Cerebrovascular, and Cognitive Function in Spinal Cord Injury
Increased life expectancy in individuals with spinal cord injury (SCI) present clinicians with the challenge of managing the secondary complications of SCI with the chronic diseases common in an aging population.
- Trial name
- NCT02122991
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries (SCI), Sleep Disordered Breathing (SDB)
Comparing CPAP and BiPAP for Sleep-Disordered Breathing in People with Cervical Spinal Cord Injuries
Sleep-disordered breathing (SDB) is common in individuals with cervical spinal cord injuries, with studies suggesting prevalence rates ranging from 27% to 62%.
- Conditions
- Spinal Cord Injuries (SCI), Sleep Disordered Breathing (SDB), Sleep Apnea, Cervical Spinal Cord Injruy
- Trial name
- NCT06818604
- Testing
- CPAP, BiPAP
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Spinal Cord Injury, Autonomic Dysreflexia
The Effects of Normalizing Blood Pressure on Cerebral Blood Flow in Hypotensive Individuals With Spinal Cord Injury
Dysregulation of blood pressure (BP), secondary to decentralized autonomic nervous system (ANS) control of the cardiovascular system, often results in chronic hypotension and orthostatic hypotension (OH) in persons with spinal…
- Conditions
- Spinal Cord Injury, Autonomic Dysreflexia, Baroreceptor Integrity, Sympathetic Integrity
- Trial name
- NCT02893553
- Testing
- Midodrine Hydrochloride, Pyridostigmine Bromide, Mirabegron
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries
Early BOTOX After Spinal Cord Injury
The investigators would like to improve our understanding of how early intervention with the use of bladder chemodenervation can preserve bladder function in those with a new SCI.
- Trial name
- NCT06793683
- Testing
- Bladder chemodenervation (Botox)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
Spinal Cord Injury
Impact of Age on Cardiovascular, Cerebrovascular and Cognitive Health in Spinal Cord Injury
As the spinal cord injured population ages, these individuals are being exposed to an increased prevalence of age-associated diseases, which coupled with the secondary complications of the injury may contribute to the reduced…
- Trial name
- NCT01984476
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Pain, Autonomic Dysreflexia
Treatment of Pain and Autonomic Dysreflexia in Spinal Cord Injury With Deep Brain Stimulation
The purpose of this research study is to determine if DBS is a feasible, safe and effective therapy for pain and autonomic dysreflexia after spinal cord injury.
- Trial name
- NCT02006433
- Testing
- Deep Brain Stimulation
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Jonathan Jagid
Parkinson Disease, Dystonia
Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia
This study will determine if posture and heart rate variability will significantly improve in Parkinsons disease with camptocormia after osteopathic manual treatments dystonia.
- Conditions
- Parkinson Disease, Dystonia, Autonomic Dysreflexia
- Trial name
- NCT03307161
- Testing
- osteopathic manual therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York Institute of Technology
Autonomic Dysreflexia
Botox for Neurogenic Detrusor Overactivity and the Prevention of Autonomic Dysreflexia Following SCI
The purpose of this study is to investigate the impact of 200 U intradetrusor injected OnabotulinumtoxinA (Botox®, Allergan, Inc.) (20 sites, trigone sparing) for neurogenic detrusor overactivity (NDO) and its role on reducing…
- Trial name
- NCT02298660
- Testing
- BOTOX
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Rick Hansen Institute
Spinal Cord Injury, Autonomic Dysreflexia
Treatment of Post-SCI Hypotension
While treatment strategies for OH have been identified for use in persons with acute SCI, the field of SCI medicine lacks a gold standard for treatment thresholds and well-defined outcome parameters.
- Conditions
- Spinal Cord Injury, Autonomic Dysreflexia, Orthostatic Hypotension, Baroreceptor Integrity
- Trial name
- NCT02919917
- Testing
- Midodrine Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center