Clinical trials: Autonomic Imbalance
Ventricular Septal Defect, Closure; Interventricular Septum
The Effect of Transcatheter Ventricular Septal Defect Closure on Heart Rate Variability Parameters
In this study; we evaluated the heart rate variability parameters of pediatric patients whose VSDs were closed with the transcatheter method before and after, and compared with the control group.
- Conditions
- Ventricular Septal Defect, Closure; Interventricular Septum, Autonomic Nervous System Imbalance
- Trial name
- NCT04859036
- Testing
- 24 hours ambulatory Holter monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Prehypertension, Blood Pressure
HIRREM for Pre-Hypertension
This randomized, controlled clinical pilot trial will evaluate the effects associated with in-office use of closed-loop, acoustic stimulation neurotechnology (High-resolution, relational, resonance-based, electroencephalic…
- Conditions
- Prehypertension, Blood Pressure, Autonomic Nervous System Imbalance, Cardiovascular Risk Factor
- Trial name
- NCT03332043
- Testing
- HIRREM, Ambient Nature Sounds
- Sponsor
- Wake Forest University Health Sciences
Syncope
Propranolol to Treat Fainting in Children With Sympathoadrenal Imbalance
This study will examine the effectiveness of the drug propranolol in preventing fainting in patients with sympathoadrenal imbalance (SAI).
- Trial name
- NCT00093860
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Autonomic Nervous System Imbalance, Healthy
Effects of OMT on ANS: a Thermography Study
the study will investigate the effect of a specific type of touch intervention on the activity of autonomic nervous system measured using thermography
- Trial name
- NCT03888456
- Testing
- osteopathic treatment
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Come Collaboration
Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance
Effects of Transcutaneous Vagus Nerve Stimulation in Older Adults
The autonomic nervous system consists of two branches, the sympathetic and the parasympathetic, which must work in balance. Its functioning can be measured indirectly by heart rate variability, which is the time between…
- Conditions
- Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance, Transcutaneous Vagus Nerve Stimulation
- Trial name
- tVNS_older (NCT07292623)
- Testing
- Active location tVNS
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Peripheral Artery Disease, Endothelial Dysfunction
Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function in PAD
Peripheral arterial disease (PAD) constitutes a major public health burden. The incidence of PAD increases with age and is associated with other comorbid cardiovascular disorders.
- Conditions
- Peripheral Artery Disease, Endothelial Dysfunction, Autonomic Imbalance
- Trial name
- TVS-PAD (NCT03445754)
- Testing
- TVS
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma
Attention-deficit/Hyperactivity Disorder, Autonomic Nervous System Imbalance
Brain Tissue Integrity and Autonomic Function Alterations in Childhood OSA and ADHD, and After Adenotonsillectomy.
Obstructive sleep apnea (OSA) and attention-deficit/hyperactivity disorder (ADHD) are two common, severe disorders in children. Unfortunately, pediatric OSA is closely associated with ADHD, and both diseases can cause cognitive…
- Conditions
- Attention-deficit/Hyperactivity Disorder, Autonomic Nervous System Imbalance, Obstructive Sleep Apnea of Child
- Trial name
- NCT04732572
- Testing
- Sleep and healthy lifestyle education, Other supportive care, Adenotonsillectomy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Anesthesia; Reaction, Autonomic Imbalance
Analysis of Autonomic Function During Anesthesia Using Response Surface Model
Anesthesia in the modern age is at least a two-drug process consisting of an opioid and a sedative hypnotic (e.g., fentanyl and propofol in combination, among others).
- Trial name
- NCT03072069
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Central University
Schizophrenia, Schizoaffective Disorder
The Effects of tDCS on Auditory Hallucination, Insight, Neurocognitive Function and HRV in Patients With Schizophrenia
The study aimed to investigate whether transcranial direct current stimulation could modify auditory hallucination, insight, neurocognitive function, heart rate variability, psychosocial functioning and quality of life in…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Auditory Hallucination, Verbal, Neurocognitive Dysfunction
- Trial name
- NCT03388554
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Schizophrenia, Schizoaffective Disorder
Theta tACS During Working Memory Training: A Pilot Study of the Effects on Negative Symptoms of Schizophrenia
In this randomized double-blind trial, we investigated whether externally induced left-hemispheric frontoparietal theta synchronization by multi-electrode online theta (6Hz) transcranial alternating current stimulation (tACS)…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Negative Symptoms, Working Memory Training
- Trial name
- NCT04545294
- Testing
- Theta tACS
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Traumatic Brain Injury, Dysautonomia
Dysautonomia and Systemic Interactions in Traumatic Brain Injury
Following brain injury, complex interactions between the nervous system and other organs are frequently encountered. Systemic effects may be induced by dysregulation of the hypothalamic-pituitary-adrenal axis and the autonomic…
- Conditions
- Traumatic Brain Injury, Dysautonomia, Sympathetic; Imbalance, Inflammation, Brain
- Trial name
- DYSI-TBI (NCT05515640)
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Karolinska University Hospital
Diabetes Mellitus, Essential Hypertension
Autonomic Imbalance and 24-h Blood Pressure Change in Patients With Chronic Renal Disease
Many patients with chronic renal disease show a loss of the nocturnal decline of blood pressure (non-dipper). However, the mechanism is not yet fully understood.
- Conditions
- Diabetes Mellitus, Essential Hypertension, Renal Failure, Chronic Nephropathy
- Trial name
- NCT00298129
- Testing
- Ambulatory blood pressure monitoring
- Where
- Japan
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Yokohama City University Medical Center
Autonomic Imbalance
Alterations in Bioelectric Activity at Acupuncture Points Following CV4 Cranial Manipulation
By measuring specific electrical parameters at acupuncture points that have been shown to correlate with ANS activity, the objectives of this study were to: 1) determine if CV4 has any influence on the bioelectric properties of…
- Trial name
- NCT05190731
- Testing
- Osteopathic cranial manipulative medicine
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Jan T Hendryx
Frailty, Autonomic Nervous System Imbalance
Unobtrusive Technologies for Monitoring of Autonomic Nervous System Function in Elderly Frail Patients
To develop and investigate an unobtrusive technology for long-term monitoring of autonomic nervous system (ANS) function's response to daily physical stressors and exercise training for elderly patients with different frailty…
- Trial name
- FrailHeart (NCT04636970)
- Testing
- Home training program
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Lymphoma, Autonomic Imbalance
Ivabradine in the Management of Cardiac Autonomic Dysfunction Associated With Thoracic Radiation Therapy.
This study will explore whether ivabradine lowers heart rate, and thus improves exercise capacity, in survivors of lymphoma who have an elevated resting heart rate as a side effect of prior radiation treatment.
- Conditions
- Lymphoma, Autonomic Imbalance, Cancer Survivorship
- Trial name
- NCT03137537
- Testing
- Ivabradine
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Dana-Farber Cancer Institute
Colitis, Ulcerative, Sleep Quality
Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis
Ulcerative colitis(UC) is one of the two main forms of inflammatory bowel disease(IBD), which seriously affects the quality of life of patients.
- Conditions
- Colitis, Ulcerative, Sleep Quality, Gastrointestinal Microbiome, Autonomic Nervous System Imbalance
- Trial name
- NCT06359808
- Where
- China
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Autonomic Dysfunction, Autonomic Imbalance
Autonomic Cardiovascular Control in Response to Blood Volume Reduction in Blood Donors
The function of the autonomic nervous system can be assessed using baroreflex sensitivity (BRS) and heart rate variability (HRV).
- Conditions
- Autonomic Dysfunction, Autonomic Imbalance, Blood Loss
- Trial name
- NCT04499664
- Testing
- Monitoring of the autonomic nervous system
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Brachial Plexus Block, Horner Syndrome
The Effects of Horner's Syndrome Developing After Interscalene Brachial Plexus Block on Autonomic Nervous Activity
This study evaluates the effects of Horner's syndrome on cardiac autonomic nervous activity after interscalene brachial plexus block.
- Conditions
- Brachial Plexus Block, Horner Syndrome, Autonomic Imbalance
- Trial name
- NCT03514342
- Testing
- Interscalene brachial plexus block, 0.75% ropivacaine
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Daegu Catholic University Medical Center
Physical Activity, Autonomic Nervous System Imbalance
Brisk Walking Study in Nursing Home Residents
It is well established that physical activity reduces the physiological effects of ageing. Among them, the decrease of the autonomic nervous system activity (ANS) is associated with the increase of cardiovascular events and sleep…
- Trial name
- NCT03302923
- Testing
- Brisk walking
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Clinique Mutualiste Chirurgicale de la Loire
Ischemic Stroke, Thrombotic Stroke
Autonomic Neuromodulation by Transcutaneous Nerve Stimulation in Acute Ischaemic Stroke.
Autonomic modulation by transcutaneous vagal nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: a phase IIa, sham controlled randomised trial.
- Conditions
- Ischemic Stroke, Thrombotic Stroke, Autonomic Dysfunction, Autonomic Imbalance
- Trial name
- VANS (NCT05417009)
- Testing
- trans-cutaneous auricular sensory stimulation
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Queen Mary University of London