Clinical trials: Autonomic Nervous System Modulation
Stress and Anxiety
The Effect of the Modified Mitchell Relaxation Method on Acute Cardiac Autonomic Modulation
The purpose of this multi-center, randomized controlled trial is to investigate the acute effects of the standard Laura Mitchell Physiological Relaxation Method versus a Modified Mitchell Relaxation Version on cardiac autonomic…
- Trial name
- NCT07713407
- Testing
- Modified Mitchell Relaxation Exercises, Standard Mitchell Relaxation Exercise
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Malignant Tumor (Cancer), MRI Examination-induced Anxiety
Multisensory Interventions Reduce MRI Anxiety in Cancer Patients
MRI-related anxiety is prevalent among cancer patients and frequently undermines imaging quality by inducing motion artifacts or causing premature examination termination.
- Trial name
- NCT07692412
- Testing
- Guzheng music therapy, Lavender aromatherapy
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Coronary Heart Disease (CHD), Anxiety Disorders
Closed-Loop Neurofeedback Targeting the Right Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With Anxiety
The goal of this clinical trial is to test whether real-time fNIRS-BCI neurofeedback targeting the right dorsolateral prefrontal cortex (right DLPFC), using active volitional control during a slow-wave auditory acoustic paradigm…
- Trial name
- HEART-SET-1 (NCT07238920)
- Testing
- Real-time fNIRS-ECG neurofeedback
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Shenyang Medical College
Chronic Kidney Diseases
Influence of Exercise in Patients With Chronic Kidney Disease During Hemodialysis
Introduction: Chronic Renal Failure affects a large part of the world population, being characterized by irreversible renal tissue damage, resulting in systemic disturbances that negatively affect the patient's life.
- Trial name
- NCT03556540
- Testing
- physical exercise
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Metodista de Piracicaba
Coronary Artery Bypass Grafting (CABG) Surgery, Vagus Nerve Stimulations
Vagus Nerve Stimulation for Autonomic Modulation After Coronary Artery Bypass Graft Surgery
The objective of this randomized clinical trial is to investigate whether transcutaneous auricular vagus nerve stimulation (taVNS) can improve the recovery of patients undergoing coronary artery bypass grafting (CABG) through…
- Trial name
- ENV (NCT07853222)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- 2 sites in Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Ischemic Preconditioning
Effects of Ischemic Preconditioning on Conditioned Pain Modulation and Heart Rate Variability in Knee Osteoarthritis
Introduction: Musculoskeletal disorders have affected approximately 1.3 billion people worldwide. Evidence shows that chronic diseases and musculoskeletal conditions often occur together, and among them it is estimated that more…
- Trial name
- NCT05059652
- Testing
- Ischemic Preconditioning
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Paulista University
Autonomic Nervous System Modulation
Effects of Autonomic Nervous System Modulation on Heart Rate Variability and Musculoskeletal Manifestations in Patients With Chronic Neck Pain
Background: Chronic neck pain is a widespread musculoskeletal disorder. Studies investigating the effect of autonomic nervous system (ANS) modulation in chronic neck pain are scarce.
- Trial name
- NCT05922059
- Testing
- Transcutaneous vagus nerve stimulation, Heart rate variability biofeedback, Standard-care physiotherapy
- Volunteers
- 102 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Autonomic Nervous System Modulation
Estimation of Autonomic Nervous System Modulation by Pulse Plethysmographic Analysis
Novel pulse plethysmography-derived indexes has been proposed as a tool to measure autonomic nervous system modulation in anaesthetized and awake patients, but nowadays a physiologic validation is lacking.
- Trial name
- NCT01966198
- Testing
- Tilt test
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- ASST Fatebenefratelli Sacco
Vagal Nerve Stimulation, Autonomic Nervous System
Vagal Response and Cardiac Autonomic Modulation. Insides From Cryoballoon Ablation
The investigators sought to evaluate the incidence and influence of vagal response observed during cryoballoon-based pulmonary vein isolation on the cardiac autonomic nervous system (CANS) and ablation outcomes in paroxysmal…
- Conditions
- Vagal Nerve Stimulation, Autonomic Nervous System, Catheter Ablation
- Trial name
- NCT04896424
- Testing
- cryoballoon-based pulmonary veins isolation
- Volunteers
- 296 people
- Sponsor
- Pomeranian Medical University Szczecin
Viral Bronchiolitis
Respiratory Physical Therapy on the Cardiac Autonomic Modulation Paediatric Patients
The present study investigated the influence of respiratory affections on the heart rate variability (HRV) of paediatric patients.
- Trial name
- NCT01354561
- Testing
- Respiratory physical therapy
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Hemiplegic Stroke
INSPIRATORY MUSCLE TRAINER ON AUTONOMIC MODULATION AND PULMONARY FUNCTION
Stroke individuals with hemiplegia often display difficulties in mobility, cardiopulmonary function...etc. All stroke patients had restrictive pulmonary dysfunction.
- Trial name
- NCT06899698
- Testing
- Inspiratory muscle training, Traditional Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Adly A Adam
Phototherapy, Autonomic Nervous System
Effects of Phototherapy Associated With Sprint and Squat Training on Cardiac Autonomic Modulation
Recent studies have shown positive results in the application of phototherapy for the improvement of performance and acceleration of the healing process of the body homeostasis.
- Conditions
- Phototherapy, Autonomic Nervous System, Training
- Trial name
- NCT03566186
- Testing
- Phototherapy, Passive recovery
- Where
- Brazil
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Paulista University
Gastro Esophageal Reflux
The Effect of Autonomic Modulation on Symptoms in Patients With Reflux Hypersensitivity
Reflux hypersensitivity is the disease that causes chest pain, heartburn and regurgitation and can impair patients' quality of life.
- Trial name
- NCT04253444
- Testing
- slow deep breathing
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Queen Mary University of London
Breast Neoplasms, Autonomic Nervous System Diseases
Effect of Exercise Training in Autonomic Modulation in Breast Cancer Patients
The aim of this study is to evaluate the effect of exercise training in the autonomic nervous system activity in breast cancer patients, who underwent doxorubicin medication.
- Trial name
- NCT02584712
- Testing
- Combined Exercise Training
- Volunteers
- 18 people
- Sponsor
- Federal University of Maranhao
Fibromyalgia, Exercise
Cardiovascular Autonomic Function and Endogenous Pain Modulation
The study has three aims: 1. To investigate the influence of cardiovascular autonomic function on pain sensitivity at rest in patients with fibromyalgia and age- and sex-matched controls 2.
- Conditions
- Fibromyalgia, Exercise, Pain, Autonomic Dysfunction
- Trial name
- NCT03911609
- Testing
- Exercise, Cognitive Task
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Marquette University
Critical Care, Weaning
Heart Rate Variability During Weaning From Mechanical Ventilation
The discontinuation of mechanical ventilation (MV) and the recovery of spontaneous breathing can lead to important cardiovascular alterations due to changes in the intrathoracic pressure.
- Trial name
- NCT00851825
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Stress, Physiological, Stress, Psychological
Autonomic Modulation Training for Police Exposed to Post-Traumatic Stress Injuries
Police officers are exposed to hazardous, disturbing events that impose stress and long-term trauma. Upwards of 15-26% of public safety personnel (PSP) report one or more mental health symptoms.
- Trial name
- AMT (NCT05521360)
- Testing
- Autonomic Modulation Training
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Atrial Fibrillation
Atrial Fibrillation Ablation and Autonomic Modulation Via Thorascopic Surgery
This study aims at investigating the role of autonomic modulation of AF. Therefore, totally thoracoscopic PV isolation with additional ablation of ganglionated plexi (GP) will be studied against PV isolation alone.
- Trial name
- AFACT (NCT01091389)
- Testing
- Totally Thoracoscopic PV isolation
- Where
- Netherlands
- Volunteers
- 240 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Insulin Resistance, Autonomic Dysfunction
Role of Endothelin-1 Modulating Insulin-stimulated Blood Flow and Sympathetic Nervous System Activity in Obesity
The aim of this project is to determine role for ET-1 in individuals with obesity.
- Conditions
- Insulin Resistance, Autonomic Dysfunction, Obesity
- Trial name
- NCT05518422
- Testing
- Hyperinsulinemic, euglycemic infusion
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Complex Regional Pain Syndromes, CRPS (Complex Regional Pain Syndromes)
Long-term Pain Modulation by Intravenous Esketamine in CRPS
Intravenous administration of esketamine is an effective recognized therapeutic option in refractory pain in CRPS, which sometimes in at least a part of the patients has a prolonged therapeutic effect.
- Trial name
- KetCRPS-2 (NCT05212571)
- Testing
- S-ketamine infusion inpatient setting, S-ketamine infusion outpatient setting
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Erasmus Medical Center