Clinical trials: Autonomic Nervous System Modulation
Autonomic Dysfunction
Cardiac Autonomic Modulation in Older Hypertensive Individuals Submitted to Different Types of Physical Training
Sixty-one sedentary older hypertensive individuals were randomized to four groups: continuous aerobic training (CA), interval aerobic training (IA), resistance training (R), and control (C) group.
- Trial name
- NCT05135247
- Testing
- Exercise
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Autonomic Nervous System Diseases
Aerobic Physical Training and Heart Rate Variability in Hypertersion
This study compared the changes in the cardiovascular, hemodynamic and metabolic variables of hypertensive patients who received aerobic physical training with intensity determined by the protocol of double non-exhaustive efforts…
- Trial name
- NCT03064256
- Testing
- Physical training program
- Volunteers
- 63 people
- Sponsor
- University of Campinas, Brazil
Healthy
Aerobic Training on the Autonomic Modulation in Children
The heart rate variability is a tool used to asses non-invasive cardiac autonomic. In fact, many studies have been disseminated of heart rate variability in adults, however few results in a literature this parameters in pediatric…
- Trial name
- NCT02236117
- Testing
- Aerobic Training
- Where
- Brazil
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Pain, Neuropathic, Complex Regional Pain Syndromes
Modulating Neuropathic Pain With Transcranial Direct Current Stimulation
This study will examine whether a form of non-invasive brain stimulation can help reduce pain in people with persistent neuropathic pain.
- Conditions
- Pain, Neuropathic, Complex Regional Pain Syndromes, Phantom Limb Pain, Spinal Cord Injuries
- Trial name
- NCT04581525
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Susan McDowell
Hypertension, Pre Hypertension
Breathing Exercises of CardioBreath Application on Autonomic and Vascular Function in Hypertension
Hypertension is one of the greatest public health challenges, affecting more than one billion people worldwide and representing a significant financial and public health burden.
- Trial name
- CardioBreath (NCT06917729)
- Testing
- CardioBreath
- Where
- 2 sites in Brazil
- Volunteers
- 66 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Intervention Affecting Autonomic Nervous System
Autonomic Nervous System Modulation During Laparoscopic Prostatectomy
The purpose of this study is to measure the variations of autonomic nervous system (ANS) modulation directed to the heart and vessels induced by pneumoperitoneum and steep trendelenburg position.
- Trial name
- NCT01927380
- Testing
- steep trendelenburg position with pneumoperitoneum
- Where
- Italy
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- ASST Fatebenefratelli Sacco
Participants Scheduled for Surgery Under Spinal Anesthesia Without Impairment of Renal, Hepatic, Cardiac or Respiratory Function
Autonomic Modulation After Spinal Anesthesia With Depth of Anesthesia and Vital Signs.
Spinal anaesthesia has the advantage that produced nerve block by the injection of local anaesthetic into cerebrospinal fluid (CSF).
- Trial name
- NCT04275375
- Testing
- observation study about the autonomic response after spinal anesthesia
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- National Central University
Spinal Cord Injuries
Autonomic Modulation in Athletes and Non-Athletes With Spinal Cord Injury During Task in Virtual Reality Environment
The study consisted in the analysis of the autonomic modulation of the heart rate by the Heart Rate Variability of the participants at rest for 5 minutes, and during physical activity of 8 minutes, through a virtual reality game.
- Trial name
- NCT04618003
- Testing
- Adaptation of autonomic nervous system to activity in virtual reality
- Where
- Brazil
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Kidney Disease
Depressed Cardiac Autonomic Modulation in Patients With Chronic Kidney Disease Diagnosed by Spectral Analysis
Background/Aims: To evaluate the sympathovagal balance in patients with chronic kidney disease (CKD) on conservative treatment. Methods: In a cross-sectional study, patients with CKD stages 3, 4 and 5 not yet on dialysis (CKD…
- Trial name
- HRV (NCT01376635)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Core Educational Research and Treatment in Nephrology
Healthy Adult Male and Female Volunteers
Diaphragmatic Breathing and Stimulation of the Autonomic Nervous System
Introduction: Slow, deep breathing has demonstrated beneficial effects on the autonomic nervous system, particularly by increasing parasympathetic activity through vagal nerve modulation.
- Trial name
- NCT07445113
- Testing
- Guided breathing at 6 breaths per minute (bpm) with an inspiration (I) to expiration (E), Guided breathing at 6 bpm with apnea (A), Breathing education
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Takotsubo Syndrome
Autonomic Modulation in Takotsubo Syndrome
This is a minimal risk case-controlled single arm intervention study, including 10 patients with a prior history of takotsubo and 10-age and sex matched healthy controls.
- Trial name
- NCT03324529
- Testing
- Tako Breath
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
Atrial Fibrillation
Atrial Fibrillation Ablation and Autonomic Modulation Via Thoracoscopic Surgery, 10 Year Follow up.
This observational study investigates the long-term outcomes of patients ten years after their participation in a previous study on the surgical treatment of atrial fibrillation (AF).
- Trial name
- AFACT-10 (NCT06493591)
- Volunteers
- 200 people
- Sponsor
- Amsterdam UMC
Atrial Fibrillation
Effects of Exercise Training in Patients With Permanent Atrial Fibrillation
Atrial fibrillation (AF) is a common arrhythmia. The proposed patholophysiological mechanisms of AF include abnormal electrical conduction in atrium and sympathovagal imbalance with increased vagal tone.
- Trial name
- NCT01721863
- Testing
- Exercise training
- Where
- Taiwan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation, Postoperative, Postoperative Complications
Transcutaneous Autonomic Modulation in Thoracic Surgery
In this study, the investigators aim to determine whether non-invasive autonomic modulation decreases inflammation and complications after thoracic surgery.
- Conditions
- Atrial Fibrillation, Postoperative, Postoperative Complications, Inflammation
- Trial name
- TON-POINTS (NCT02783157)
- Testing
- Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Duke University
Mental Health Conditions, University Students
Effect of Sun Tai Chi on the Cardiopulmonary System and Mental Health in University Students
Currently, university students face physical and mental health issues, which are reflected in low levels of physical activity, a decline in healthy eating behaviors, and a high prevalence of mental health symptoms such as stress…
- Trial name
- NCT07044154
- Testing
- Tai Chi (Sun Style), Health lifestyle education
- Where
- Chile
- Volunteers
- 56 people
- Sponsor
- Universidad Católica del Maule
Ageing, Aerobic Exercise
Acute Exercise Effects on Arterial Stiffness and Cardiovagal Modulation in Adults
Background and Gap: The physiological importance of large artery distensibility in cardiovascular function is well-established. Stiffening of central arteries leads to elevated systolic blood pressure (SBP), increased left…
- Conditions
- Ageing, Aerobic Exercise, Resistance Exercise, Combined Exercise
- Trial name
- PUMPING ARTERY (NCT06616428)
- Testing
- Bike group fitness class, Pump Power, Global Training
- Where
- Portugal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Cardiac Resynchronization Therapy, Chronic Heart Failure
Exercise Training Following Cardiac Resynchronization Therapy in Patients With Chronic Heart Failure
Cardiac resynchronization therapy(CRT) is recommended to reduce mortality and morbidity in chronic heart failure(CHF) patients New York Heart Association(NYHA) class III-IV who are symptomatic despite optimal medical therapy…
- Trial name
- NCT02413151
- Testing
- Exercise training program, Cardiac resynchronization therapy (CRT)
- Where
- Portugal
- Volunteers
- 62 people
- Sponsor
- University of Lisbon
Periodontitis, Cardiac Electrophysiology
Effects of Periodontitis on Heart Rate Variability
Periodontitis is a chronic inflammatory disease associated with systemic inflammatory burden and possible alterations in autonomic nervous system regulation.
- Trial name
- NCT07735312
- Testing
- Non-surgical periodontal therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Premature Ventricular Complexes, PVC - Premature Ventricular Contraction
Sustained Auricular Nerve Stimulation for PVC Suppression
Non-invasive vagus nerve stimulation has been clinically tested for the treatment cardiac arrhythmias. However, prior studies have shown mixed results-possibly in part due to inadequate stimulation duration.
- Conditions
- Premature Ventricular Complexes, PVC - Premature Ventricular Contraction, Auricular Vagus Nerve Stimulation
- Trial name
- SANS-PVC (NCT07093034)
- Testing
- Extended nocturnal use of auricular vagus nerve stimulator device
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of California, San Diego
Prediabetes
Effects of Autonomic Nervous System Modulation by Heart Rate Variability Biofeedback Training With Resonant Frequency Breathing on Glucose Metabolism in Individuals With Prediabetes
Approximately 20% of adults have prediabetes in Germany. Prediabetes is defined as a condition with glucose levels outside the normal range but not yet meeting the criteria for type 2 diabetes.
- Trial name
- RwHRVBFinPD (NCT06739993)
- Testing
- Resonance frequency breathing with heart rate variability biofeedback training, Anti-Stress program
- Where
- 2 sites in Germany
- Volunteers
- 60 people
- Sponsor
- Johannes Gutenberg University Mainz