Clinical trials: Autonomous Nervous System
Delirium, Confusion
Intelligent Intensive Care Unit
Delirium, as a common complication of hospitalization, poses significant health problems in hospitalized patients. Though about a third of delirium cases can benefit from intervention, detecting and predicting delirium is still…
- Trial name
- ICU_Delirium (NCT02465307)
- Testing
- Confusion Assessment Method, Accelerometer, Commercially available camera
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Florida
Arterial Hypertension, Atrial Fibrillation
Effect of Renal Denervation on Atrial Fibrillation
The purpose of the ERDAF study (Effect of Renal Denervation on Atrial Fibrillation) is to evaluate the renal sympathetic denervation in patients with resistant arterial hypertension and symptomatic paroxysmal or persistent atrial…
- Trial name
- ERDAF (NCT04055285)
- Testing
- Sympathetic Renal Denervation, Implantable Loop Recorder
- Volunteers
- 30 people
- Sponsor
- Hippocration General Hospital
Autonomous Nervous System, Fatigue
Exploring Physiological Responses of Virtual Reality Walking Exercise Versus Treadmill Walking in Healthy Individuals
This study aimed to systematically compare the physiological responses generated by walking exercises conducted in a VR environment versus those performed on a treadmill, with a specific focus on their impacts on the autonomic…
- Trial name
- NCT06679348
- Testing
- walking exercise on treadmill, Treadmill walking exercise using VR
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atlas University
Postoperative Delirium, Postoperative Neurocognitive Disorder
Risk Warning Model of Postoperative Delirium and Long-term Cognitive Dysfunction in Elderly Patients
The incidence of postoperative delirium in elderly patients is high, which can lead to long-term postoperative neurocognitive disorders. Its high risk factors are not yet clear.
- Conditions
- Postoperative Delirium, Postoperative Neurocognitive Disorder, Surgery
- Trial name
- NCT06423547
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Autism Spectrum Disorder
Emotional Proactive Brain Study in Adults With Autism Spectrum Condition
This project aims: to study behavioral and cerebral activity specificity (latency and amplitude of evoked potentials, time frequency maps and cerebral connectivity) in predictive process (top-down regulation) during visual…
- Trial name
- PREDEMAUT (NCT04069676)
- Testing
- EEG
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Myasthenia Gravis
The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis
ME\&MG is a standalone software (digital solution) running on patients smartphones, connected to a web portal for physicians. It is intended to be used as an unsupervised digital self-assessment tool for the monitoring of…
- Trial name
- NCT05564936
- Testing
- ME&MG mobile application
- Where
- 19 sites in United States, France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ad scientiam
Pain, Distress
Acupuncture for Pain During Injection of Local Anaesthetic
Stimulation of acupoint LI4 has been shown to result in analgesic effects in patients experiencing acute pain. We aimed to determine whether LI4 acupuncture could reduce pain and distress in children receiving an injection of a…
- Conditions
- Pain, Distress, Satisfaction
- Trial name
- AcuDent (NCT02197546)
- Testing
- Acupuncture & acupressure
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University Medicine Greifswald
Cardiovascular Insufficiency
Passive Leg Raising - an Important Diagnostic Manoeuvre
The aim is to describe the physiological background for PLR and the interpretation of a PLR manoeuvre. The protocol entails the measurement of stroke volume (SV) at baseline (semirecumbent patient position), during PLR and after…
- Trial name
- PLR-ANS (NCT03454802)
- Testing
- Passive Leg Raising
- Where
- Denmark
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Region MidtJylland Denmark
Syncope
Autonomous Syncope Onset Prediction and Prevention
syncope prediction on tilt table
- Trial name
- NCT02684539
- Testing
- tilt table Erigo®
- Volunteers
- healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Aminoglycoside Toxicity, Aminoglycoside-Induced Hearing Loss
Video Game Hearing Tests for Remote Monitoring of Ototoxicity
The reason for this clinical trial is to test different ways of carrying out hearing tests to be able to detect for hearing loss within the hospital and at home.
- Conditions
- Aminoglycoside Toxicity, Aminoglycoside-Induced Hearing Loss, Hearing Loss, Video Games
- Trial name
- VAROT (NCT05847556)
- Testing
- video game hearing tests, Audio-training
- Where
- 2 sites in United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Stroke, Adrenal Incidentaloma
Association Between Stroke and Adrenal Incidentalomas
Adrenal incidentalomas (AIs) are commonly encountered in transsection imaging which purpose not for suspected adrenal disease. However, part of AIs in patients is associated with Stroke.
- Trial name
- ABSAI (NCT05237817)
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Xuanwu Hospital, Beijing
Infectious Disease, Cardiovascular Diseases
Metabolic and Infectious Diseases in La Réunion (the REUNION Population-based Study)
The aim of the present study is to determine the prevalence of cardiometabolic and infectious disease in La Reunion (french oversea department and region of France).
- Conditions
- Infectious Disease, Cardiovascular Diseases, General Population, Metabolic Disease
- Trial name
- NCT05400824
- Testing
- Blood, DNA, feces, urine, hair and skin microbiota collection
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pain, Delirium
Fundamental Intelligent Building Blocks of the Intensive Care Unit (ICU) of the Future: Intelligent ICU of the Future
The objective of this project is to create deep learning and machine learning models capable of recognizing patient visual cues, including facial expressions such as pain and functional activity.
- Trial name
- NCT03905668
- Testing
- Video Monitoring, Accelerometer Monitoring, Electromyographic Monitoring
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Florida
Healthy Volunteers, Cardiovascular System
Effects of Transcutaneous Electrical Stimulation on the Autonomous Nerve System in Healthy Young People
Cardiovascular disease is one of the most important causes of death and disability in the world. An autonomic imbalance is associated to cardiovascular risks and disorders.
- Conditions
- Healthy Volunteers, Cardiovascular System, Autonomic Nervous System
- Trial name
- ESautonomous (NCT05289817)
- Testing
- Transcutaneous Vagus Nerve Stimulation (t-VNS), Transcutaneous Sympathetic Ganglion Electrical Stimulation (t-SES)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Anxiety, Relaxation
A Single Mindfulness Meditation Session in Preoperative Anxiety : Effects on the Autonomous Nervous System
Anxiety is an emotional disorder. It's a painful concern caused by uncertainty. It is a complex phenomenon misunderstood in spite of medical progress. Relaxation is a technical for reduce anxiety and is effective and safe.
- Trial name
- NCT03324048
- Testing
- relaxation session
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pupillary Function, Abnormal, Cerebral Aneurysm
Impact of Acute Cerebral Diseases on the Autonomous Nervous System: Progression and Correlation to Therapy and Outcome
The pupilometer determines the alteration of the pupil diameter after a defined light stimulus. In this study data is collected from pupilometer measurements of patients with an acute cerebral disease.
- Trial name
- Pupillometry (NCT02999659)
- Testing
- Pupilometer
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- RWTH Aachen University
General Anesthesia
Analgesia Nociception Index Guided Remifentanil Administration During Propofol Anesthesia for Laparoscopic Surgery
The Physiodoloris (MetroDoloris, Lille, France) monitor, CE marqued, uses the ECG signal in order to compute the Analgesia Nociception Index (ANI) which has been shown to measure the relative parasympathetic tone, and hence to…
- Trial name
- AIVOC-ANI (NCT01893723)
- Testing
- ANI guided remifentanil, ANI blind arm
- Where
- 5 sites in Belgium, France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Lille
Premature Birth, Newborn
Pain Management in Neonatal Intensive Care Units by Studying the Autonomic Balance
Fight against the pain caused by the disease or by the diagnostic and therapeutic procedures is a daily and essential concern for the caregiver neonatologist.
- Trial name
- NIPE-DOL (NCT02764424)
- Testing
- NIPE (MDoloris®)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
Neuropsychological Management of Multiple Sclerosis: Benefits of a Computerised Semi-autonomous At-home Cognitive Rehabilitation Programme
Multiple sclerosis (MS) is a central nervous system inflammatory disease that causes a chronic and progressive physical handicap.
- Trial name
- SEPIA (NCT03471338)
- Testing
- Cognitive rehabilitation, Standard Psychological care
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Caen