Clinical trials: Avascular Necrosis of Bone of Hip
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
BC Study of G7 Cup and Compatible Femoral Stems
A prospective , observational, multi-centre, cohort study of the G7™ Acetabular System used with compatible femoral stems in patients with degenerative disease of the hip. The study will be enrolled onto Beyond Compliance.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- NCT03456622
- Where
- United Kingdom
- Volunteers
- 230 people
- Sponsor
- Zimmer Biomet
Non Traumatic Osteonecrosis of the Femoral Head (Hip)
Safety, Tolerability, and Preliminary Efficacy of Intra-Articular Injection of Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Non-Traumatic Avascular Necrosis of the Femoral Head
This is a first-in-human, single-arm, open-label, dose-escalation, exploratory Phase I clinical trial designed to evaluate the safety, tolerability, and preliminary efficacy of local injection of mesenchymal stem cell-derived…
- Trial name
- NCT07787923
- Testing
- Exosome Intervention Group
- Volunteers
- 15 people
- Sponsor
- Beijing Jishuitan Hospital
Coxarthrosis, Avascular Necrosis of Hip
Effect of Peri-operative Glucocorticoids on Short-term Functional Outcome After THA
This randomized, single surgeon, placebo controlled, double blind study will be conducted in order to investigate whether or not peri-operative high doses of intravenous glucocorticoids improve short-term functional outcome after…
- Trial name
- DEXA (NCT04317872)
- Testing
- High dose of peri-operative intravenous dexamethasone, Low dose of peri-operative intravenous dexamethasone
- Where
- Belgium
- Volunteers
- 71 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Osteoarthritis, Arthritis
Periprosthetic Bone Mineral Density After Total Hip Arthroplasty Performed Through a Minimally Invasive Anterior Approach (AMIS) With Either an AMIStem or a Quadra Femoral Component
This is a monocentric, prospective, randomized clinical survey to verify if the periprosthetic remodelling brought about either the AMIStem or the Quadra femoral component is equivalent.
- Conditions
- Osteoarthritis, Arthritis, Avascular Necrosis, Fracture of the Femoral Neck or Head
- Trial name
- NCT01285843
- Testing
- Anterior Minimally Invasive Approach (AMIS)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Medacta International SA
Joint Disease
Post Market Clinical Follow-Up Study Protocol for PROFEMUR® Gladiator HA Coated Modular Femoral Stems
MicroPort Orthopedics (MPO) is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) and resurfacing components marketed in the European Union (EU).
- Trial name
- NCT02314611
- Testing
- PROFEMUR® Gladiator HA Coated Modular Femoral Stem
- Where
- Belgium
- Volunteers
- 154 people
- Sponsor
- MicroPort Orthopedics Inc.
Joint Disease
Post Market Clinical Follow-up Study Protocol for PROFEMUR® Xm Femoral Stems
MicroPort Orthopedics (MPO) is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) and resurfacing components marketed in the European Union (EU).
- Trial name
- NCT02309593
- Testing
- PROFEMUR® Xm Femoral Stems
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- MicroPort Orthopedics Inc.
Rheumatoid Arthritis, Congenital Hip Dysplasia
A Clinical Trial Study of Hip System in Primary Total Hip Arthroplasty in China
A clinical trial of total Hip system used in Primary Total Hip Arthroplasty in China.
- Conditions
- Rheumatoid Arthritis, Congenital Hip Dysplasia, Avascular Necrosis
- Trial name
- NCT02399007
- Testing
- Total Hip System made in China (SUN, CoCr, Duraloc, Marathon), Total Hip System made outside of China (Summit, CoCr, Duraloc, Marathon)
- Where
- 8 sites in China
- Volunteers
- 160 people
- Sponsor
- Johnson & Johnson Medical (Suzhou) Ltd.
Bone Marrow, Femoral Neck Fractures
Bone Marrow Injection in Fracture of Femoral Neck
Objectives: Primary objective : To investigate the predisposing factors for femoral neck fractures, including age, sex, and associated comorbidities.
- Trial name
- NCT07808294
- Testing
- Anatomical reduction and fixation with bone marrow injection, Anatomical reduction with Fixation
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Yaser Alkanash
Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck
Z1 Hip System: Post-Market Clinical Follow Up Study
The objectives of this study are to confirm the early to mid- term safety, performance, and clinical benefits of the Z1 Femoral Hip System in hemi- and primary total hip arthroplasty.
- Conditions
- Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck, Avascular Necrosis of the Femoral Head
- Trial name
- NCT07104279
- Testing
- Z1 Femoral Hip System
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Arthrosis, Traumatic Arthritis
The Medacta International SMS Post-Marketing Surveillance Study
This is a Post-Marketing Surveillance of SMS femoral stem prosthesis.
- Conditions
- Arthrosis, Traumatic Arthritis, Rheumatoid Polyarthritis, Congenital Hip Dysplasia
- Trial name
- NCT02748408
- Testing
- SMS femoral stem
- Where
- 4 sites in Austria, Italy and 2 more
- Volunteers
- 550 people
- Sponsor
- Medacta International SA
Hip Dysplasia, Legg-Calvâe-Perthes Disease
Mixed-Methods Evaluation of Short-, Medium-, and Long-Term Outcomes Following Hip Treatment
This study, titled "Mixed-Methods Evaluation of Short-, Medium-, and Long-Term Outcomes Following Hip Treatment," aims to assess the long-term effectiveness of treatments for pediatric hip conditions, including hip dysplasia…
- Conditions
- Hip Dysplasia, Legg-Calvâe-Perthes Disease, Avascular Necrosis of Hip
- Trial name
- NCT06891196
- Testing
- Long-term Follow-up Surveys
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Subchondral Cysts, Subchondral Bone Edema
SCP Hip Outcomes Study
Post-market clinical outcomes study to collect data on the short- and long-term outcomes for subjects who are undergoing or have undergone the Subchondroplasty® (SCP®) Procedure in the hip in a standard clinical setting.
- Conditions
- Subchondral Cysts, Subchondral Bone Edema, Bone Marrow Edema, Insufficiency Fractures
- Trial name
- NCT03494660
- Testing
- Subchondroplasty Procedure with AccuFill
- Where
- 6 sites in United States
- Volunteers
- 77 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Hip, Avascular Necrosis of the Femoral Head
Ceramic-on-Ceramic Versus Ceramic-on-HXLPE THA
Methods to reduce the revision rate of total hip arthroplasties (THAs) because of wear-related issues are important to examine, particularly because younger patients have a disproportionately high risk of revision.
- Conditions
- Osteoarthritis, Hip, Avascular Necrosis of the Femoral Head, Arthropathy of Hip, Hip Arthr
- Trial name
- NCT03639532
- Testing
- COC THA, COP THA
- Volunteers
- 148 people
- Sponsor
- Ewha Womans University
Hip Osteoarthritis, Avascular Necrosis
Insignia™ Hip Stem Outcomes Study
The objective of this study is to evaluate the safety and effectiveness of the Insignia™ Hip Stem for global market access and post-market clinical follow-up up to 10 years postoperative.
- Conditions
- Hip Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
- Trial name
- NCT05144191
- Testing
- Insignia uncemented Hip Stem
- Where
- 11 sites in United States
- Volunteers
- 313 people
- Sponsor
- Stryker Orthopaedics
Avascular Necrosis of Hip, Total Hip Replacement Arthroplasty
Rotational Thromboelstometry (ROTEM) change_colloid_total Hip Replacement Arthroplasty
The investigators administered different kinds of colloids before transfusion of red blood cell to patient undergoing total hip replacement arthroplasty.
- Trial name
- NCT01512628
- Testing
- Pentaspan, voluven, volulyte
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis, Avascular Necrosis
Metal on Metal Versus Metal on Highly Crossed Linked Polyethylene Sytem
This trial will evaluate the 36mm or greater metal head on metal hip system and compare it to the 32mm or 28mm metal head on polyethylene (liner) hip system in patients receiving a primary cementless total hip replacement.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Congenital Dysplasia of the Hip
- Trial name
- MOM (NCT01422564)
- Testing
- Metal on Metal Hip System, Highly Cross Linked Polyethylene cup System
- Volunteers
- 41 people
- Sponsor
- Nova Scotia Health Authority
Osteoarthritis, Avascular Necrosis of Bone of Hip
Vivacit-E Post-market Follow-up Study
The objectives of this study are to obtain clinical performance (outcomes) data and survivorship for commercially available Vivacit-E (HXPE) liners.
- Conditions
- Osteoarthritis, Avascular Necrosis of Bone of Hip, Post-traumatic; Arthrosis, Congenital Hip Dysplasia
- Trial name
- NCT03226808
- Testing
- Vivacit-E Liner
- Where
- 5 sites in United States
- Volunteers
- 245 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Avascular Necrosis
Trinity™ BIOLOX Delta™ CoC THR Multi-center Study
To demonstrate the safety and effectiveness of the Trinity™ BIOLOX delta™ Ceramic-on-Ceramic Total Hip System in comparison to the Trinity™ Acetabular Hip System,which is FDA cleared for use in the U.S.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, CDH
- Trial name
- NCT01921309
- Testing
- Trinity CoC Total Hip System, Trinity Ceramic-on-Poly THR
- Where
- 10 sites in United States, United Kingdom
- Volunteers
- 342 people
- Sponsor
- Corin
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
A Clinical Investigation of the M2a- Taper™ Hip System
The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the M2a- Taper™ Hip System
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis
- Trial name
- NCT00698633
- Volunteers
- 43 people
- Sponsor
- Biomet Orthopedics, LLC
Rheumatoid Arthritis, Osteoarthritis
A Multi-centre Study to Assess the Long-term Performance of the DePuy PROXIMA™ Hip in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of the DePuy PROXIMA™ hip in the treatment of patients with hip joint disease requiring a total hip replacement.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- NCT00208455
- Testing
- DePuy Proxima™ Hip
- Where
- 4 sites in Germany, Italy and 2 more
- Volunteers
- 184 people
- Sponsor
- DePuy International