Clinical trials: Awakening Early
ICU Delirium, Immobility
Awakening-Breathing Coordination, Delirium Monitoring/Management & Early Mobility (ABCDE) Protocol
Fully two-thirds of ICU patients develop delirium, which is associated with longer stays, billions of dollars in costs globally, and 3-fold excess mortality at 6 months.
- Trial name
- ABCDE (NCT01413009)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Nebraska
Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders
Light Exposure to Treat Sleep Disruption in Older People
The purpose of this study is to test whether shifts in the timing of the biological clock to a later hour (phase delay shifts of the human circadian system) can be produced in response to four successive evenings of light…
- Conditions
- Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders, Hypersomnia
- Trial name
- NCT00427323
- Testing
- light exposure
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Insomnia
Sleep Restriction Therapy for Insomnia in Primary Health Care
The recommended treatment for insomnia, cognitive behavioral therapy for insomnia (CBT-I), is effective. However, its long, multi-component nature makes it challenging to implement in ordinary primary care, where most people are…
- Trial name
- NCT04975776
- Testing
- Sleep restriction therapy, Sleep hygiene
- Where
- Sweden
- Volunteers
- 104 people
- Sponsor
- Region Stockholm
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Sleep Disorders, Physical Activity
Health Promotion in Early Adolescence: Sleep, Activity, and Emotion Regulation
The primary goal of this project is to examine the short and long-term effects of an intervention focusing on three interrelated dimensions of health: improving sleep, increasing physical activity, and improving skills in emotion…
- Conditions
- Sleep Disorders, Physical Activity, Depression, Anxiety
- Trial name
- NCT01289197
- Testing
- Family Check Up
- Where
- United States
- Volunteers
- 324 people
- Sponsor
- University of Pittsburgh
Obstructive Sleep Apnea, OSA
Early Feasibility Study of Transcutaneous Upper Airway Stimulation in Obstructive Sleep Apnea
Early feasibility study to estimate the functionality of a novel intervention based on non-invasive transcutaneous electrical stimulation of the hypoglossal nerve to reduce the Apnea Hypopnea Index (AHI).
- Trial name
- NCT05881512
- Testing
- Transcutaneous Upper Airway Stimulation Device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Somnial Inc
Intensive Care Unit Syndrome, Prediction
Machine Learning-based Longitudinal Study of Post-ICU Syndrome Development Trajectory in Critically Ill Patients and Construction of Clinical Early Warning Models: a Research Protocol for Longitudinal Study
This project intends to track and evaluate whether post-ICU syndrome will occur 7 days, 1 month, 3 months and 6 months after ICU patients are transferred out of the ICU through a longitudinal study, apply the latent category…
- Conditions
- Intensive Care Unit Syndrome, Prediction, Cognitive Impairment, Sleep Disorder
- Trial name
- NCT06427265
- Where
- China
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital Of Guizhou Medical University
Obstructive Sleep Apnea (OSA), Insomnia Chronic
Effective of Early Treatment of Insomnia on the Adherence of CPAP
This study includes patients suffering from both sleep apnea and insomnia. All participants receive treatment with CPAP. Half of the participants additionally receive a digital program to treat insomnia, initiated at the same…
- Trial name
- CoPAP (NCT07556432)
- Testing
- digital CBT-I, CPAP
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Atherosclerosis, Cardiovascular Risk Factor
Early Vascular Ageing in the YOUth
This is a single-center observational study on adolescents to determine predictors of the early steps of the formation of atherosclerosis and to quantify their influence on Intima-Media-Thickness of the carotid artery and the…
- Conditions
- Atherosclerosis, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Pathology
- Trial name
- EVA4YOU (NCT04598685)
- Where
- Austria
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Covid19, Obstructive Sleep Apnea
Early Application of Continuous Positive Airway Pressure in Coronavirus Patients at Risk of Obstructive Sleep Apnea
This was an experimental clinical trial, Aim: To evaluate the role of early use of Continuous Positive Airway Pressure (CPAP) in management of moderate to severe Coronavirus disease 2019 patients at risk of Obstructive Sleep…
- Conditions
- Covid19, Obstructive Sleep Apnea, CPAP Ventilation, Corona Virus Infection
- Trial name
- NCT05934916
- Testing
- CPAP ( Continuous positive airway pressure), oxygen therapy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Insomnia, Nightmares Associated With Trauma and Stress
Restorative Early Sleep Treatment After the Emergency Department
The goal of this randomized controlled trial is to pilot the virtual delivery of cognitive behavioral therapy for insomnia (CBT-I) and nightmares (CBT-I\&N) via telehealth as an early intervention for treating posttraumatic sleep…
- Conditions
- Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
- Trial name
- RESTED (NCT07121270)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Depression Anxiety Disorder, Demography, Family
The Effect of Mindfulness-based Stress Reduction Programme Given to Infertile Women
Purpose of the Study This study aims to determine the effect of mindfulness-based stress reduction program given to infertile women on perceived stress, anxiety, depression and salivary cortisol.
- Conditions
- Depression Anxiety Disorder, Demography, Family, Awakening Early
- Trial name
- NCT06283693
- Testing
- mindfulness-based stress reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Valve Heart Disease, Awakening Early
Prospective Evaluation of Volatile Sedation After Heart Valve Surgery
Cardiac surgery is a complex operative procedure with a substantial risk of postoperative complications, so that patients undergoing valve surgery are usually transferred to the intensive care unit postoperatively.
- Trial name
- NCT04958668
- Testing
- Post-operative intensive care using volatile sedation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Goethe University
Sleep, Circadian Rhythm
HEARTBEAT SOUND FOR BREASTFEEDİNG DİFFİCULTİES: A RANDOMİZED CONTROLLED TRİAL
This randomized controlled trial aims to evaluate the effect of listening to a pre-recorded, standardized maternal heartbeat sound on perceived stress levels and breastfeeding self-efficacy in mothers experiencing early…
- Conditions
- Sleep, Circadian Rhythm, Pregnancy, Newborn
- Trial name
- NCT07881484
- Testing
- Standardized Maternal Heartbeat Sound Application
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hakan Avan
Breast Self-Examination, Breast Cancer
Experimental Study With Pretest/Posttest Groups Which the Intervention Group Have the System Which Sends Reminder Notifications Directing Them to the Website Containing BSE Training Along With the Illustrations Created for the Practice Prepared by the Researcher on the Determined Ideal Day
H0: Among the intervention and control groups of reminder notifications relating to self-examination H01: Average breast cancer fear score and H02: There is no difference in the average score of breast cancer health beliefs.
- Conditions
- Breast Self-Examination, Breast Cancer, Nursing Caries, Cancer
- Trial name
- BreastSelfExam (NCT05995483)
- Testing
- Early Diagnosis on BSE
- Where
- Cyprus
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Obstructive Sleep Apnea
Evaluation of an Early Management Strategy for Obstructive Sleep Apnea
The primary objective of this study is to evaluate the effect of more timely care for obstructive sleep apnea (OSA) on adherence to positive airway pressure (PAP) therapy at three months after treatment initiation.
- Trial name
- NCT04613414
- Testing
- Early Management
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- University of Calgary
Sleep Apnea Syndrome
Effect of Early Education on the Observance of CPAP Treatment
Sleep apnea (SA) affects more than 4% from general population and is largely underdiagnosed. SA can increase the occurrence of cardiovascular, endocrine and metabolic events (particularly stroke, diabetes \& obesity).
- Trial name
- CoachSAS (NCT02657304)
- Testing
- Coaching group, Control group
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pediatric Sleep Problems, Sleep Hygiene
Storybook App vs Cognitive Behavioral Therapy for Child Sleep and Attachment
This completed randomized controlled trial compared two caregiver-delivered interventions for sleep in young children: a multimodal mobile health intervention delivered through the Storybook mobile application and a face-to-face…
- Conditions
- Pediatric Sleep Problems, Sleep Hygiene, Parent-Child Attachment
- Trial name
- STORYBOOK-RCT (NCT07668609)
- Testing
- CBT-Based Psychoeducational Intervention, Storybook Mobile Application Intervention
- Where
- Ecuador
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Cuenca
Delirium, Sleep Disorders, Circadian Rhythm
Study of Sleep and Delirium in the Intensive Care Unit (ICU)
The investigators will perform a prospective, cohort study of 100 older intensive care unit (ICU) patients, to investigate the association between sleep disruption and ICU delirium.
- Trial name
- SID (NCT01280097)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of California, San Francisco
Osteopathy, PreTerm Neonate
The Effect of Cranial Osteopathy Intervention in Preterm Babies
There are planing to have 2 groups of premature born cases. Each group will include 15 cases. Participants are need to be 28-37 weeks born and no older than post term 6 weeks. All cases are going to be evaluated.
- Conditions
- Osteopathy, PreTerm Neonate, Sensory Profiles, Colic
- Trial name
- NCT06967870
- Testing
- Osteopathic intervention, Home based exercise education
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University