Clinical trials: Awareness, Anesthesia
Anaesthesia
"Light" Versus "Deep" Bispectral Index (BIS) Guided Sedation for Colonoscopy
In this trial, patients undergoing elective colonoscopy under sedation will be randomised to BIS-guided sedation targeting either "light" (bispectral index [BIS] 70-80) or "deep" (BIS<60) sedation.
- Trial name
- NCT01457274
- Testing
- Sedation depth
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Melbourne Health
Anaesthesia, Anesthesia Depth Monitoring
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients
Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures.
- Trial name
- ANIGAPP (NCT07245654)
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Awareness During General Anesthesia
Is Density Spectral Array Display Along With Bispectral Index Superior to the Display of Bispectral Index Alone
A study to evaluate the use of density spectral array display in comparison with Bispectral index in a clinical setting.
- Trial name
- DSA-Light (NCT07232160)
- Testing
- Depth of anesthesia monitoring using processed EEG
- Where
- Australia
- Volunteers
- 70 people
- Sponsor
- The University of Queensland
Explicit Recall of Intra-operative Events
Study Evaluating Ways of Preventing Patients From Being Awake During High-Risk Surgery and Anesthesia
The overall purpose of this study is to see if a Bispectral Index (BIS) monitor, a Food and Drug Administration (FDA) approved brain monitoring device, will help to reduce the risk of patients remembering being awake during…
- Trial name
- NCT00281489
- Testing
- BIS Monitor guided algorithm, Volatile anesthetic guided algorithm
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Washington University School of Medicine
Anesthesia Awareness
The Depth of Paediatric Anaesthesia: Observational Trial
Perioperative measurement of the Depth of anaesthesia is currently recommended part of daily anaesthesia good clinical practice. The optimal depth of anaesthesia measured by Bispectral index could be between 40-60.
- Trial name
- ANAPED (NCT05193747)
- Testing
- Anesthesia depth monitoring
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Intraoperative Awareness
Effect of Remifentanil on the Bispectral Index in Women Undergoing Caesarean Delivery Under General Anaesthesia
Patients undergoing caesarean delivery under inhalation anaesthesia are at a high risk of awareness, especially in the period before delivery.
- Trial name
- NCT03508102
- Testing
- remifentanil
- Volunteers
- 60 people
- Sponsor
- West China Second University Hospital
Surgery-Complications, Anesthesia Complication
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major…
- Conditions
- Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia
- Trial name
- THRIVE (NCT05991453)
- Testing
- Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent
- Where
- 24 sites in United States
- Volunteers
- 13,000 people
- Sponsor
- Washington University School of Medicine
Awareness, Anesthesia, Post Traumatic Stress Disorder
Psychological Effect of Explicit Recall After Sedation (PEERS)
Awareness, or explicit recall, under sedation is often intended and expected by anesthesiologists and is assumed that does not associate with any sequelae.
- Conditions
- Awareness, Anesthesia, Post Traumatic Stress Disorder, Depression
- Trial name
- PEERS (NCT04747379)
- Where
- Canada
- Volunteers
- 2,500 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Anxiety, Anesthesia
The Effect of Awareness on Preoperative Anxiety
In the majority of patients, anxiety and fear are observed at different levels before surgery. Preoperative anxiety was reported in 60-80% of the patients who underwent surgery.
- Trial name
- NCT03389581
- Testing
- awareness and anxiety
- Where
- Turkey (Türkiye)
- Volunteers
- 799 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Intraoperative Awareness
The Impact of Maternal Sound on Awareness for Pediatric Patients Undergoing Cardiac Surgery
Awareness during anesthesia with intraoperative memory occurs when the patient is able to process information and produce specific responses to several stimuli.
- Trial name
- NCT02583295
- Testing
- Music sound, Maternal sound
- Where
- Egypt
- Volunteers
- 309 people
- Sponsor
- Assiut University
Accidental Awareness During General Anesthesia
Prevalence of AAGA
Accidental Awareness During General Anesthesia (AAGA) is a condition where patients regain partial or full consciousness during anesthesia, unable to move or react.
- Trial name
- NCT06759974
- Where
- Turkey (Türkiye)
- Volunteers
- 459 people
- Sponsor
- Marmara University
Awareness, Anesthesia, Arteriovenous Malformations
Awake Craniotomy for Arteriovenous Malformation
The study aimed to retrospectively review cases of brain arteriovenous malformation that were surgical resected with the patient awake during the procedure.
- Trial name
- NCT04949815
- Where
- Pakistan
- Volunteers
- 4 people
- Sponsor
- Aga Khan University
Intraoperative Awareness
Relationship Between Bispectral Index (BIS) and Spectral Entropy (SpEn) During Desflurane Anaesthesia
The aim of this study was to estimate the relationship between BIS and Spectral Entropy values and any explicit or implicit memory or dreams recall during desflurane anaesthesia.
- Trial name
- NCT01868178
- Testing
- BIS and Spectral Entropy
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Anastomotic Leak Small Intestine, Anastomotic Leak Large Intestine
Enhanced Perioperative Care for the Prevention of Colorectal Anastomotic Leakage
This multicenter open-label trial is designed to evaluate if the implementation of an enhanced peri-operative care protocol results in an optimal intraoperative condition of the patient and in a decrease in incidence of…
- Conditions
- Anastomotic Leak Small Intestine, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum, Intraoperative Awareness
- Trial name
- DOUBLE CHECK (NCT05250882)
- Testing
- Enhanced perioperative care protocol
- Where
- 9 sites in Belgium, Netherlands
- Volunteers
- 1,600 people
- Sponsor
- Amsterdam UMC, location VUmc
Anesthesia Awareness
Glasgow Coma Scales and General Anesthesia
The study evaluates the general anesthesia management with BIS monitorization in terms of hemodynamic stability, drug concentrations and drug consumption in patients who underwent surgery due to intracranial pathology and who…
- Trial name
- NCT03521414
- Testing
- Bispectral index (BIS) monitoring, Sevoflurane
- Volunteers
- 45 people
- Sponsor
- Trakya University
Surgery--Complications, Anesthesia Complication
THRIVE Feasibility Trial
To evaluate the feasibility of a pragmatic, large scale, comparative effectiveness, randomized evaluation of patient experience of intravenous propofol versus inhaled volatile anesthesia.
- Conditions
- Surgery--Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia Emergence Delirium
- Trial name
- THRIVE (NCT05346588)
- Testing
- Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Awareness, Anesthesia
Validity of Perfusion Index to Evaluate the Level of General Anaesthesia in Children.
The aim of this study is to evaluate the validity of perfusion index to determine the level of anesthesia in comparison with auditory evoked potential in children undergoing tonsillectomy.
- Trial name
- PI/AAI (NCT03412214)
- Testing
- Perfusion index detected by pulse oximeter, AAI
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Assiut University
Anaesthesia
Dreaming During Anaesthesia and Anaesthetic Depth
Patients commonly report that they have been dreaming when they awaken from general anaesthesia. Our hypothesis is that patients who report dreaming are less deeply anaesthetised during anaesthesia than patients who do not report…
- Trial name
- NCT00226876
- Where
- 3 sites in Australia
- Volunteers
- 300 people
- Sponsor
- Melbourne Health
Awareness, Anesthesia
Knowledge and Awareness of Instruments Sterilization Protocols Among Healthcare Workers in Operation Theater
In the medical field, the sterilization of instruments is a crucial component of any surgical procedure. It's important for healthcare workers to have a fundamental understanding of how to properly sterilize and disinfect…
- Trial name
- NCT07054580
- Testing
- knowledge and awareness
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Superior University