Clinical trials: Axillary Dissection
Breast Cancer Surgery, Post Operative Pain
The Effects of Peri-Operative Pregabalin on Post-Operative Pain Following Breast Cancer Surgery With Axillary Node Dissection: A Pilot Study
Breast cancer is a devastating disease. Some women with breast cancer undergo surgery to remove the breast and lymph nodes in the axilla (armpit).
- Trial name
- NCT00852683
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Nova Scotia Health Authority
Breast Cancer, Chemotherapy
ALND vs ART in Positive Sentinel Node After Neoadjuvant Therapy in Breast Cancer
In the case of primary surgery, in patients with sentinel node involvement, it has already been shown that omitting axillary lymph node dissection (ALND), often combining axillary radiotherapy (RT), does not worsen the prognosis…
- Conditions
- Breast Cancer, Chemotherapy, Sentinel Lymph Node, Axillary Lymph Nodes Dissection
- Trial name
- ADARNAT (NCT04889924)
- Testing
- Axillary Radiotherapy, Lymphadenectomy
- Where
- 61 sites in Australia, Spain
- Volunteers
- 820 people
- Sponsor
- Hospital Universitari de Bellvitge
Lymphedema, Breast Cancer, Lymphedema
LYMPHA Procedure for the Prevention of Lymphedema After Axillary Lymphadenectomy
Lymphedema is a chronic, progressive, and debilitating condition that occurs with disruption or obstruction of the lymphatic system, which commonly occurs a result of breast cancer therapy.
- Trial name
- NCT05366699
- Testing
- axillary lymphadenectomy with immediate lymphatic reconstruction (LYMPHA), Axillary lymphadenetomy alone, axillary lymphadenectomy with soft tissue reinforcement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Breastcancer, Surgery: Axillary Dissection
Anti-adhesive Effect and Safety of a Mixed Solid of Poloxamer, Gelatin and Chitosan(Mediclore®) After Axillary Dissection for Breast Cancer
Anti-adhesive effect and Safety of a mixed solid of poloxamer, gelatin and chitosan(Mediclore®) after axillary dissection for breast cancer
- Trial name
- NCT02967146
- Testing
- adhesive barrier
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Samsung Medical Center
Postoperative Complications
Impact of Oral Diets on Postoperative Fluid Collection
Patients after the surgical removal of axillary lymphnodes suffers from prolonged fluid collections. The aim of the study is to assess the impact of oral immunonutrition and high-protein diets on the reduction of fluid collection.
- Trial name
- BC1 (NCT05068882)
- Testing
- Immunonutrition, High-protein nutrition, Standard nutrition
- Where
- 2 sites in Poland
- Volunteers
- 400 people
- Sponsor
- Stanley Dudrick's Memorial Hospital
Breast Cancer
Targeted Axillary Dissection After Neo-adjuvant Chemotherapy
Currently most breast cancer patients with confirmed axillary lymph node metastasis (cN1) at diagnosis are candidates for neoadjuvant chemotherapy (NAC).
- Trial name
- NCT05071911
- Testing
- TAD (Targeted Axillary Dissection)
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Breast Cancer, Axillary Lymph Nodes Dissection
Audit of Targeted Sentinel Node Biopsy (TSNB) in Patients With Limited Nodal Disease Undergoing Primary Surgery
Axillary ultrasound scan (AUS) is routinely employed in the UK for preoperative axillary staging and can diagnose approximately 50 - 80% of node positive patients when combined with percutaneous needle biopsy techniques (either…
- Conditions
- Breast Cancer, Axillary Lymph Nodes Dissection, Axillary Metastases, Sentinel Lymph Node Biopsy (SLNB)
- Trial name
- NodeSMART (NCT07085442)
- Testing
- Targeted Sentinel Node Biopsy (TSNB)
- Where
- 14 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Breast Neoplasms
Preventing Seroma Formation After Axillary Lymph Node Dissection for Breast Cancer by Early Vacuum Assisted Closure
Axillary dissection is the standard treatment for breast cancer patients with positive nodes. However, seroma formation after axillary dissection remains the most common early complication to breast cancer surgery.
- Trial name
- NCT01731769
- Testing
- vacuum assisted closure in experimental arm, Axillary dissection
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
Breast Cancer
Sentinel Lymph Node Biopsy in Patients With Breast Cancer After Neoadjuvant Therapy
The aim of this study is to create clear indications for Sentinel Lymph Node Biopsy (SLNB) or Axillary Dissection (AD) in women with breast carcinoma after neoadjuvant therapy by studying the false negative rate of SLNB.
- Trial name
- NCT03556397
- Testing
- Sentinel lymph node biopsy (SLNB), Axillary dissection
- Where
- 2 sites in Czechia
- Volunteers
- 61 people
- Sponsor
- University Hospital Ostrava
Invasive Breast Cancer
Sentinel Lymph Node Biopsy in Clinically Node-negative Early Breast Cancer Patients After Neoadjuvant Chemotherapy
This is a prospective, single-center, non-randomized, non-controlled observational study.
- Trial name
- NCT03381092
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Peking University
Breast Neoplasms
Study of Fluorodeoxyglucose (FluGlucoScan) in Patients With Breast Cancer: Correlation With Histologic Findings of Sentinel Node Biopsies and Axillary Dissection
Breast cancer affects many women. One of the places to which it can spread is the lymph glands under the arm. The type of treatment offered to patients often will depend on whether those lymph glands have cancer in them or not.
- Trial name
- NCT00123799
- Testing
- Positron Emission Tomography Imaging
- Where
- Canada
- Volunteers
- 199 people
- Sponsor
- AHS Cancer Control Alberta
Mastectomy, Segmental, Acute Pain
Evaluation of a Breast Biblock Analgesia for the Mastectomy With Radical Axillary Lymphadenectomy Surgery
This study evaluates the efficacy of the the pecto-intercostal fascial plane block (PIF block) for the anesthesia of the intercostal nerves anterior branches and assesses the association of the serratus block with a PIF block for…
- Conditions
- Mastectomy, Segmental, Acute Pain, Anesthesia
- Trial name
- NCT02963857
- Volunteers
- 9 people
- Sponsor
- Maison de Santé Prostestante de Bordeaux Bagatelle
Breast Cancer
Ideal Marker for Targeted Axillary Dissection
A multicentre prospective comparative study, comparing the use of various markers (magnetic marker Magseed, iodine seed 125I, carbon suspension) for marking a pathological lymph node in patients with breast carcinoma prior to…
- Trial name
- IMTAD (NCT04580251)
- Testing
- Targeted axillary dissection
- Where
- 5 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Malignant Melanoma
Suction Drain in Axillary Lymph Node Dissection for Malignant Melanoma
Postoperative complications like seroma formation and wound site infection readily occur following completion axillary lymph node dissection (ALND) for malignant melanoma.
- Trial name
- NCT04648163
- Where
- Austria
- Volunteers
- 118 people
- Sponsor
- Medical University of Graz
Breast Cancer
Prospective Evaluation of Targeted Axillary Dissection (TAD)
The purpose of this research is to evaluate how to manage the axillary lymph nodes in patients with breast cancer. The investigators will determine if a sampling of the lymph nodes under the arm will give the information…
- Trial name
- TAD (NCT04998682)
- Testing
- Axillary Dissection
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Breast Cancer Lymphedema
Effect of ALND With Vein Branches Reservation on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the effects of axillary lymph node dissection with or without axillary vein branches reservation on the affected upper limb edema and dysfunction in breast cancer patients, and to explore…
- Trial name
- PLEDGE-Surgery (NCT05120180)
- Testing
- axillary lymph node dissection with vein branches reservation, axillary lymph node dissection without vein branches reservation
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Axillary Dissection
Axillary Reverse Mapping for Breast Carcinomas
Distinct arm from breast axillary dissection (AD), or axillary reverse mapping (ARM), involves retrieving all breast related nodes while leaving intact the main lymphatic drainage chain of the upper limb.
- Trial name
- SENTIBRAS (NCT01146158)
- Testing
- Axillary dissection for breast carcinomas
- Where
- France
- Volunteers
- 210 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer
Does Scar Massage Improve Postoperative Pain and Function in Women With Breast Cancer?
All patients undergoing breast cancer surgery are left with scars which can significantly affect their physical and psychological well being.
- Trial name
- NCT00175344
- Testing
- Scar massage.
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Breast Cancer, Muscle Strength
Effectiveness of PNF Training for Improving for Muscle Strength, Function, and Pain After Axillary Lymph Node Dissection
Breast cancer is the most common type of cancer affecting women of all ages worldwide. Advanced and comprehensive treatment options have increased survival rate and life expectancy, necessitating a focus on the complications of…
- Trial name
- NCT05288036
- Testing
- Proprioceptive Neuromuscular Rehabilitation group, Progressive Resistance Exercise Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
in Situ Breast Cancer, Invasive Breast Cancer
Suction Drain Versus the Use of Adaptive Skin Sutures After Mastectomy ± Axillary Lymphadenectomy; a Prospective Randomised Study
The objective of this prospective randomized study is to perform qualitative and quantitative comparisons between the insertion of traditional suction drains (Arm: Suction drain) versus the application of absorbable adaptive…
- Trial name
- NCT01509781
- Testing
- Insertion of suction drain(s) following mastectomy, Adaptive skin sutures.
- Where
- Hungary
- Volunteers
- 400 people
- Sponsor
- National Institute of Oncology, Hungary