Clinical trials: Axillary Dissection, active
Breast Cancer, Axillary Lymph Nodes Dissection
Audit of Targeted Sentinel Node Biopsy (TSNB) in Patients With Limited Nodal Disease Undergoing Primary Surgery
Axillary ultrasound scan (AUS) is routinely employed in the UK for preoperative axillary staging and can diagnose approximately 50 - 80% of node positive patients when combined with percutaneous needle biopsy techniques (either…
- Conditions
- Breast Cancer, Axillary Lymph Nodes Dissection, Axillary Metastases, Sentinel Lymph Node Biopsy (SLNB)
- Trial name
- NodeSMART (NCT07085442)
- Testing
- Targeted Sentinel Node Biopsy (TSNB)
- Where
- 14 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection
Effect of Serratus and Pectoralis II Plane Block Versus Pectoralis II Alone on Acute Postoperative Pain After Mastectomy
The goal of this randomized controlled clinical trial is to determine whether adding a serratus anterior plane block (SAPB) to a pectoralis II (PECS II) block improves pain relief and reduces the need for opioids in adult women…
- Conditions
- Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection, Nerve Block; Pain Medication, Pectoralis Nerve Block
- Trial name
- PECS (NCT07881237)
- Testing
- Serratus Anterior Plane Block (SAPB) group, Pectoral nerve block (PECS)
- Where
- Lebanon
- Volunteers
- 80 people
- Sponsor
- Lebanese American University
Breast Cancer, Chemotherapy
ALND vs ART in Positive Sentinel Node After Neoadjuvant Therapy in Breast Cancer
In the case of primary surgery, in patients with sentinel node involvement, it has already been shown that omitting axillary lymph node dissection (ALND), often combining axillary radiotherapy (RT), does not worsen the prognosis…
- Conditions
- Breast Cancer, Chemotherapy, Sentinel Lymph Node, Axillary Lymph Nodes Dissection
- Trial name
- ADARNAT (NCT04889924)
- Testing
- Axillary Radiotherapy, Lymphadenectomy
- Where
- 61 sites in Australia, Spain
- Volunteers
- 820 people
- Sponsor
- Hospital Universitari de Bellvitge
ALND, Sentinel Lymph Node Biopsy (SLNB)
Upfront Targeted Axillary Dissection for Luminal Breast Cancer With Limited Axillary Involvement
The present study aims to avoid axillary lymph node dissection (ALND) in patients with an Ultrasound (US) detected positive preoperative lymph node involvement (1 or 2 suspicious lymph-nodes) and a needle histology/cytology…
- Conditions
- ALND, Sentinel Lymph Node Biopsy (SLNB), Targeted Axillary Dissection (TAD)
- Trial name
- UTAD (NCT07278726)
- Testing
- Upfront Targeted Axillary Dissection (UTAD)
- Where
- 14 sites in Italy, Switzerland
- Volunteers
- 150 people
- Sponsor
- European Institute of Oncology
Axillary Lymph Node Dissection, Pathological Complete Response
Omission of ALND in Breast Cancer Patients With Axillary pCR
This prospective, single-arm, phase II trial studies axillary lymph node dissection (ALND) to see if it can be safely omitted in breast cancer patients with axillary pathological complete response (pCR) after neoadjuvant systemic…
- Conditions
- Axillary Lymph Node Dissection, Pathological Complete Response, Neoadjuvant Systemic Therapy, Breast Cancer
- Trial name
- NCT05939830
- Testing
- Stained region Lymph Node Biopsy (SrLNB), Regional lymph node radiotherapy (RNI) including the axilla
- Where
- China
- Volunteers
- 92 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Breast Cancer, Axillary Lymph Node Dissection
Nomogram to Predict Breast Cancer Related Lymphedema
It has been hypothesized that damaged arm lymphatic drainage is associated with the arm lymphedema after axillary lymph node dissection (ALND).
- Conditions
- Breast Cancer, Axillary Lymph Node Dissection, Breast Cancer Related Lymphedema, Axillary Reverse Mapping
- Trial name
- NCT04665882
- Testing
- Axillary surgery based on lymphedema prediction nomogram
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Wuhan University