Clinical trials: BACTERIAL VAGINOSIS
Bacterial Vaginoses, Infertility, Female
The Effect of Clindamycin and a Live Biotherapeutic on the Reproductive Outcomes of IVF Patients With Abnormal Vaginal Microbiota
Study question: Does antibiotic alone or in combination with live biotherapeutic treatment of an abnormal vaginal microbiota improve the reproductive outcomes of IVF couples? Study hypothesis: The investigator hypothesize that…
- Trial name
- NCT05166746
- Testing
- Clindamycin
- Where
- 4 sites in Denmark
- Volunteers
- 333 people
- Sponsor
- Peter Humaidan
Vulvovaginal Candidiasis (VVC)
An Investigation to Evaluate the Clinical Performance and Safety of pHyph in Adult Women With Vulvovaginal Candidiasis Compared With an Untreated Control Group
The goal of this clinical trial is to learn if pHyph works to reduce signs and symptoms of vulvovaginal candidiasis (thrush). It will also learn about the safety of pHyph.
- Trial name
- NCT07405853
- Testing
- pHyph
- Where
- 3 sites in Sweden
- Volunteers
- 48 people
- Sponsor
- Gedea Biotech AB
Sexually Transmitted Disease, Bacterial Vaginosis
Women's Improvement of Sexual Health (WISH) Demonstration Project
The current standard of care for urogenital infections in Rwanda is syndromic management. Many urogenital infections are asymptomatic and therefore completely missed, and the management of vaginal discharge syndrome is known to…
- Conditions
- Sexually Transmitted Disease, Bacterial Vaginosis, Vaginal Candidiasis, Urinary Tract Infections
- Trial name
- WISH (NCT03045809)
- Testing
- Urogenital infection point-of-care tests
- Where
- Rwanda
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Janneke van de Wijgert
Bacterial Vaginosis (BV), Recurrent Bacterial Vaginosis
Evaluation of the Medical Device Vagitab - T as Adjuvant Therapy in Patients With Bacterial Vaginosis.
This clinical trial is looking at how well and safely the vaginal administration of Vagitab-T works . Vagitab-T is already on the market in several countries in Europe as a medical device.
- Trial name
- Vagitab (NCT06725888)
- Testing
- Vagitab -T vaginal tablets. Components: tyndallized probiotic L. plantarum HA-119, lactic acid, and xylo-oligosaccharides, lauryl glucoside, and macrogol 3350:
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- S.I.I.T. Srl
Vaginosis, Bacterial
Study of the Composition and Bacterial Diversity of the Vaginal Microbiota in Healthy Versus Pathological Conditions (Bacterial Vaginosis) Using a Targeted Metagenomic Approach (RNA 16s)
It aims to determine and compare the degree of vaginal bacterial alpha diversity in the absence (healthy population) or presence of bacterial vaginosis (pathological population).
- Trial name
- CEBAM (NCT04989543)
- Testing
- vaginal swabs
- Where
- France
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Larena SAS
Bacterial Vaginosis, Premature Birth
Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity
The trial intends to evaluate the efficacy of specially designed probiotics to prevent premature birth and related neonatal morbidity associated to intra-uterine infection.
- Conditions
- Bacterial Vaginosis, Premature Birth, Sepsis, Periventricular Leukomalacia
- Trial name
- NCT00303082
- Testing
- Lactobacillus rhamnosus GR1 and Lactobacillus reuteri RC-14
- Where
- 2 sites in Brazil
- Volunteers
- 645 people
- Sponsor
- Oswaldo Cruz Foundation
Candidosis Vaginal
Safety and Tolerability Studies of CanProFem-AK, Vaginal Suppositories in Healthy Volunteers
The study object of this clinical trial is CanProFem-AK, 100 mg suppositories. The Pharmacological group - Antifungal drug for external use.
- Trial name
- NCT06535126
- Testing
- CanProFem-AK
- Where
- Kazakhstan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Industrial Microbiology LLP
Vaginal Infection
Evaluation of Intravaginal Gel and Ovule Formulations of TOL-463
The purpose of this study is to determine the safety, local tolerability and pharmacokinetic parameters of TOL-463 intravaginal dosage forms in both healthy, nonpregnant females following single dose administration (Part 1), and…
- Trial name
- NCT01812889
- Testing
- TOL-463 Vaginal ovule, TOL-463 Vaginal gel
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Bacterial Vaginosis, Fungal Vaginal Infections
Clinical Protocol CERN Feasibility Study
The goal of this clinical trial is to learn if the intravaginal Cern device works to treat bacterial vaginosis and fungal vaginitis in premenopausal women. It will also learn about the safety of the device.
- Trial name
- NCT06933420
- Testing
- Cern Device
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Cern Corporation
Bacterial Vaginosis and Vaginal Candidiasis At Pregnancy
Oral Probiotics for the Treatment and Prevention of Vulvovaginal Infections in Pregnancy - Double-blind, Randomized, Placebo-controlled Study
During pregnancy, bacterial vaginosis (BV), abnormal vaginal flora (AVF) and vulvovaginal candidiasis (VVC) are associated with serious complications and discomfort. Yet, treatment options are limited.
- Trial name
- NCT02795845
- Testing
- Probiotic Capsule containing L. acidophilus, L. Paracasei, L. Rhamnosus, streptococcus thermophilus and Bifidobacterium bifidum
- Where
- 3 sites in Israel
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Vaginitis
Open Study of the Efficacy of the Local Treatment With Polygynax of Bacterial and/or Mycotic Vaginitis
Open prospective multicenter phase IV study in patients presenting with symptoms of bacterial and/or mycotic (mushroom) vaginitis for 12 days as specified in the product information.
- Trial name
- NCT02444481
- Testing
- Polygynax combinaison of polymyxin, Neomycin and Nystatin
- Volunteers
- 169 people
- Sponsor
- Laboratoire Innotech International
Vaginosis, Bacterial
Exploratory Study to Evaluate the Effects of the Probiotics L. Rhamnosus GR-1 and L. Reuteri RC-14
The purpose of this study was to determine whether L. rhamnosus GR-1 and L. reuteri RC-14 delivered via capsules to the vagina of post-menopausal women over a three day course of treatment can restore and maintain a…
- Trial name
- NCT02139839
- Testing
- Lactobacillus capsules
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Kimberly-Clark Corporation
Bacterial Vaginosis
Trial of Trimosan Gel Effect on Pessary-associated Bacterial Vaginosis
The primary objective of this prospective, randomized, controlled study is to assess the effect of Trimo-San vaginal gel on the rate of bacterial vaginosis in women who use pessaries.
- Trial name
- TBVAP (NCT01471457)
- Testing
- Trimo-San gel
- Where
- 2 sites in United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
HIV Infections, Chlamydia Trachomatis
Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand
The primary aims of the study were to assess the safety and acceptability of Carraguard applied vaginally prior to sexual intercourse for six months in both women and men; and to examine several dimensions of acceptability.
- Conditions
- HIV Infections, Chlamydia Trachomatis, Nesseria Gonorrhea, Trichomonas Vaginitis
- Trial name
- NCT00213057
- Testing
- Carraguard (PC-515)
- Where
- Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Population Council
Trichomonal Vaginitis, Bacterial Vaginosis
Evaluation of Efficacy and Safety of Gynomax® XL Ovule
Efficacy and safety of Gynomax® XL ovule in the treatment of trichomonal vaginitis, bacterial vaginosis, candidal vulvovaginitis and mixed vaginal infections will be evaluated in this open label, single-arm, multicentral study.
- Conditions
- Trichomonal Vaginitis, Bacterial Vaginosis, Candidal Vulvovaginitis, Mixed Vaginal Infections
- Trial name
- Gyno-Türk (NCT03839875)
- Testing
- Gynomax® XL Vaginal Ovule
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Exeltis Turkey
Vaginal Douching, Bacterial Vaginosis
Brief, Behavioral Intervention to Reduce Douching Among Adolescent and Young Women
This study will implement and test a brief, tailored individual-level intervention to be used in two New Orleans adolescent clinics with female patients aged 16-24 who douche.
- Trial name
- NCT00207480
- Testing
- Brief, motivational interviewing intervention
- Where
- United States
- Sponsor
- Centers for Disease Control and Prevention
Bacterial Vaginosis | Vaginal | Microbiology
Efficacy and Safety of D005 Vaginal Mousse on Bacterial Vaginosis
This is a randomised, double-blind clinical investigation to evaluate the efficacy and safety of D005 vaginal mousse compared to placebo, in women with bacterial vaginosis.
- Trial name
- NCT04489290
- Testing
- D005 Vaginal Mousse
- Where
- 9 sites in Sweden, United Kingdom
- Volunteers
- 83 people
- Sponsor
- PepTonic Medical AB
Bacterial Vaginosis, Fetal Membranes, Premature Rupture
Perinatal Infections in Pakistan
There are large differences in health outcomes related to pregnancy and birth between developed and developing countries. This study will investigate how infections, medical history, health care behavior and psychosocial issues…
- Conditions
- Bacterial Vaginosis, Fetal Membranes, Premature Rupture, Chorioamnionitis, Pregnancy
- Trial name
- NCT00070746
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Vulvovaginal Candidiasis
Monthly Itraconazole Versus Classic Homeopathy for Treatment of Recurrent Vulvovaginal Candidiasis (RVVC)
A prospective study to evaluate the efficacy of classic homeopathic therapy compared to maintenance itraconazole therapy with and without additional exogenous lactobacillus for treatment of recurrent Candida vaginitis.
- Trial name
- NCT00895453
- Testing
- itraconazole, lactobacillus gasseri, classic homeopathy (carcinosin M, nux vomica, pulsatilla M, ferrum metallicum, sepia M, etc. as prescribed)
- Where
- Austria
- Volunteers
- 144 people
- Sponsor
- Medical University of Vienna
Bacterial Vaginosis, Vulvovaginal Candidiasis
Comparing NAAT Testing to Standard Methods for the Diagnosis of Vaginitis
Vaginitis is the most common condition encountered in the gynecologist's office and is most commonly caused by bacerial vaginosis (BV), vulvovaginal candidiasis (VVC) and Trichomonas vaginalis (TV).
- Conditions
- Bacterial Vaginosis, Vulvovaginal Candidiasis, Trichomoniasis
- Trial name
- VAST (NCT02203942)
- Testing
- NAAT testing
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh