Clinical trials: BDNF
Major Depression
Assessment of Pituitary Adenylate Cyclase Activating Polypeptide-Brain Derived Neurotrophic Factor (PACAP-BDNF) Signaling System Involvement in Etiology and Treatment of Major Depression
The neuropeptide Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) and its receptors PAC1 and VPAC2 are widely expressed in the nervous system.
- Trial name
- NCT00944996
- Testing
- SSRI; SNRI; TCA
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tirat Carmel Mental Health Center
Chronic Low Back Pain
Genetic Predictors of Responsiveness to Radiofrequency Denervation in Chronic Low Back Pain
The Investigators have designed this exploratory study in patients suffering from zygapophysial joint mediated pain to investigate if a correlation exists between inter-individual genetic variability (genotype) with treatment…
- Trial name
- NCT02383524
- Testing
- Lumbar Radiofrequency Medial Branch Neurolysis
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Carpal Tunnel Syndrome (CTS)
Photobiomodulation for Median Nerve Neuroplasticity in Carpal Tunnel Syndrome: A Randomized Controlled Trial
Carpal Tunnel Syndrome (CTS) is the most common peripheral entrapment neuropathy, causing pain, paresthesia, and hand dysfunction due to median nerve compression at the wrist.
- Trial name
- PBM-CTS-RCT (NCT07714720)
- Testing
- Photobiomodulation (Low-Level Laser Therapy), Routine Physiotherapy Programme
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- University of Lahore
Fibromyalgia, Transcranial Direct Current Stimulation
Long Term Home Based tDCS in Fibromyalgia
Fibromyalgia(FM) is a widespread musculoskeletal pain syndrome characterized by fatigue, sleep disorders, cognitive impairment, depressive symptoms and neuro-vegetative symptoms.
- Trial name
- NCT03843203
- Testing
- Transcranial Direct Current Stimulation - tDCS
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital de Clinicas de Porto Alegre