Clinical trials: BRONCHIAL ASTHMA
Asthma, Chronic Rhinosinusitis With Nasal Polyps
Opening the "Black Box" on Tezepelumab's Effect on Chronic Rhinosinusitis With Severe Asthma
The study explores how chronic rhinosinusitis (CRS) and asthma share a common inflammatory process, particularly affecting patients with both conditions.
- Trial name
- NCT06740045
- Testing
- Tezepelumab
- Volunteers
- 10 people
- Sponsor
- Dr. Andrew Thamboo, MD
Mild Intermittent Asthma
Effects of Core Stability Combined With Diaphragmatic Strengthening Exercises Among Asthmatic Patients
This is a quasi intervention study evaluating the effects of core stabilization exercises and diaphragmatic strengthening on thoracic kyphosis angle, diaphragmatic excursion, chest expansion, lung functioning (FEV1/FVC ratio) and…
- Trial name
- NCT06479902
- Testing
- Core stability exercise, Diaphragmatic Strengthening Exercise
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Foundation University Islamabad
Asthmatic Bronchitis
Gene Expression Profile and Inflammation Profile of Classic Asthma, Cough Variant Asthma and Eosinophilic Bronchitis
This study aims to identify and validate the gene expression differentials of peripheral blood mononuclear cells and differential inflammation profiles and other aspects in classic asthma, cough-variant asthma and eosinophilic…
- Trial name
- NCT02555345
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Asthma
Safety, Tolerability, and Pharmacokinetics of Orally Inhaled DNAzyme Solution for Nebulisation in Healthy Male Subjects
Asthma is a chronic inflammatory bronchial disorder with three distinct components: airway hyper-responsiveness (respiratory hypersensitivity), airway inflammation, and intermittent airway obstruction.
- Trial name
- NCT01470911
- Testing
- SB010
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Sterna Biologicals GmbH & Co. KG
Asthma
Effects of Pilates Exercises in Asthmatic Patients
Asthma is a chronic respiratory disease with high prevalence worldwide, considered an important cause of morbidity, mortality and high economic costs.
- Trial name
- NCT03670654
- Testing
- Pilates, Muscle stretching
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Bronchial Asthma
A Study to Evaluate the Efficacy and Safety of HSK31858 Tablets in Patients with Bronchial Asthma
This is a phase II, randomised, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of HSK31858 in patients with bronchial asthma
- Trial name
- NCT06637254
- Testing
- HSK31858
- Where
- China
- Volunteers
- 219 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Asthma
Initiation of Chronic Asthma Care Regimens in the Pediatric Emergency Department
Hypothesis: Initiating chronic management treatment plans in conjunction with an asthma educational intervention in the pediatric Emergency Department (ED) with anti-inflammatory medication will result in an improvement of ED…
- Trial name
- IRUSBUPR0045 (NCT00388739)
- Testing
- Intervention: Budesonide, Usual care: albuterol + systemic steroids
- Where
- United States
- Sponsor
- Baylor College of Medicine
Asthma
Study to Compare the Efficacy and Safety of QVM149 With QMF149 in Patients With Asthma
The purpose of the trial was to evaluate the efficacy and safety of two different doses of QVM149 (QVM149 150/50/80 μg and QVM149 150/50/160 μg via Concept1) over two respective QMF149 doses (QMF149 150/160 μg and QMF149 150/320)…
- Trial name
- NCT02571777
- Testing
- QVM149 150/50/160, QVM149 150/50/80, QMF149 150/320
- Where
- 403 sites in Argentina, Austria and 39 more
- Volunteers
- 3,092 people
- Sponsor
- Novartis Pharmaceuticals
Asthma, Rhinitis
Study of Asthma and Nasal Steroids
The trial will study the effectiveness of nasal steroids for the treatment of chronic rhinitis and/or sinusitis on asthma control.
- Conditions
- Asthma, Rhinitis, Sinusitis
- Trial name
- STAN (NCT01118312)
- Testing
- Mometasone Furoate monohydrate
- Where
- 19 sites in United States
- Volunteers
- 388 people
- Sponsor
- JHSPH Center for Clinical Trials
Asthma, Bronchial Asthma
Study of Salmeterol (SN408D) for Adult Asthma
To demonstrate the efficacy (non-inferiority) of Salmeterol 50mcg bid (100mcg/day), compared with Hokunalin (tulobuterol) tape 2mg once a day, in terms of improvement in pulmonary function (peak expiratory flow: PEF) in a…
- Trial name
- NCT00950794
- Testing
- Salmeterol(SN408D), Hokunalin (tulobuterol) tape
- Volunteers
- 367 people
- Sponsor
- GlaxoSmithKline
Asthma in Children
Promoting Partnership and Improving Self-Management for Children With Persistent Asthma
The goal of this study is to evaluate a pilot of clinic-based intervention of asthma education. After a scheduled outpatient encounter for well-child care or asthma care has concluded, a pediatric nurse will teach participants…
- Trial name
- NCT03390556
- Testing
- Nurse-delivered education
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Rochester
Asthma
A Study of the Safety and Pharmacokinetics of Levodopa Following Administration of CVT 301 (Levodopa Inhalation Powder) in Adults With Asthma
This study is a double-blind, randomized, placebo-controlled, 2-period, crossover study to evaluate safety and PK of 3 doses of CVT 301 levodopa (l-dopa) in adults with asthma.
- Trial name
- NCT02633007
- Testing
- CVT-301 (levodopa inhalation powder), Carbidopa
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Acorda Therapeutics
Asthma
Improving Asthma Control in the Real World: A Systematic Approach to Improving Dulera Adherence
40 subjects with moderate-to-severe asthma will be randomly selected for study in which 20, will be monitored for medication use (Dulera 100/5, Dulera 200/5 and Proventil HFA) over 3 months.
- Trial name
- NCT02045875
- Testing
- Dulera
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Asthma Management Systems
Asthma
Assessment of Airway Responsiveness and Treatment Efficacy in Asthmatics
Bronchial asthma is a common chronic respiratory disease. Patients usually manifest variable symptoms (such as short of breath, chest tightness, cough, etc.) and variable airflow limitation and often associated with airway…
- Trial name
- NCT02574975
- Testing
- methacholine, adenosine monophosphate, leukotriene D4
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhujiang Hospital
Severe Asthma
Educational Needs of Patients With Severe Asthma on Targeted Immunotherapies
Severe asthma is a debilitating disease that affects every aspect of patients' lives: daily life, work, social life, family life, and marital life.
- Trial name
- BASIC (NCT07856407)
- Testing
- Initial assesment interwiew, Intake Interview with the Patient
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Asthma
Efficacy and Safety of Ciclesonide Administered With or Without Different Spacers in Patients With Asthma (12 to 75 y) (BY9010/M1-145)
The aim of the present study is to investigate the efficacy and safety of ciclesonide on lung function and safety. Ciclesonide will be inhaled at one dose level once daily, using an inhaler device with or without spacer.
- Trial name
- NCT00163436
- Testing
- Ciclesonide
- Where
- 66 sites in Canada, France and 4 more
- Volunteers
- 450 people
- Sponsor
- AstraZeneca
Asthma
A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Moderate-Dose ICS Therapy.
This study is designed to determine if the investigational drug is effective and safe in individuals with asthma.
- Trial name
- NCT00603746
- Testing
- GW685698X
- Where
- 154 sites in United States, Australia and 14 more
- Volunteers
- 627 people
- Sponsor
- GlaxoSmithKline
Asthma
The Community United to Challenge Asthma
This study compares an asthma self-management intervention, delivered to the family and tailored to their needs and cultural beliefs, to standard asthma education on two risk factors for asthma exacerbations in high-risk Puerto…
- Trial name
- Project CURA (NCT01065883)
- Testing
- community health worker, mailed information
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rush University Medical Center
Asthma
Improving Asthma Care Through Parental Empowerment
The overall aim of this study will be to perform a prospective randomized clinical trial of an enhanced version of the IMPACT DC intervention involving short-term case management to facilitate PCP follow-up appointments and to…
- Trial name
- PEPAC (NCT00832923)
- Testing
- PEPAC
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's National Research Institute
Asthma
Effect of Different Doses of Budesonide on Markers of Bone Metabolism in Children With Asthma
The purpose of the trial is to check if inhaled glucocorticosteroids (iGCS) have influence on bone condition (if iGCS increases risk of osteoporosis and bone fraction) in children with asthma.
- Trial name
- NCT00487773
- Testing
- budesonide, D3 vitamin, montelukast sodium
- Where
- Poland
- Volunteers
- 96 people
- Sponsor
- Medical University of Lodz
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.