Clinical trials: BRONCHIAL ASTHMA
Asthma
Molecular Mechanism of Asthma
The aim of this study is to investigate the mechanisms whereby lung function is decreased in asthma and sensitivity to treatment.
- Trial name
- NCT00180726
- Testing
- Blood sampling, Endoscopic Bronchoscopy, Spirometry
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma
The Correlations of FeNO, Blood Eosinophils and Lung Function in Well-controlled Asthma
In Asthma, the levels of exhaled FeNO is correlated to sputum eosinophils particularly in the patient with poor controlled asthma or severe asthma.
- Trial name
- NCT04454385
- Testing
- Patients with well controlled asthma
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Hat Yai Medical Education Center
Asthma
Regular Use Tiotropium and Tolerance to Bronchoprotection in Mild Asthma
The study will assess if regular use of tiotropium (i.e. daily) results in loss of bronchoprotection against methacholine induced bronchoconstriction in those with mild asthma.
- Trial name
- NCT05113615
- Testing
- Tiotropium Bromide
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Saskatchewan
Obesity, Blood Pressure
Upstate New York Infant Development Screening Program
The goal of the Upstate KIDS Study is to track the growth, development and long-term health of children given the increasing use of infertility treatment, occurrence of maternal obesity and pregnancy complications, and rising…
- Conditions
- Obesity, Blood Pressure, Motor Delay, Developmental Delay
- Trial name
- Upstate KIDS (NCT03106493)
- Testing
- None (observational)
- Volunteers
- 6,171 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Patients With Asthma-COPD Overlap Syndrome (ACOS)
Non-interventional Study of COPD Patients With Asthma Overlap Syndrome in Viet Nam and Taiwan
The purpose of this study to determine the proportion and clinical characteristics of COPD patients with asthma symptoms (ACOS) and describe current practices in diagnosis and management in Viet Nam and Taiwan.
- Trial name
- NCT02878252
- Where
- 5 sites in Taiwan, Vietnam
- Volunteers
- 350 people
- Sponsor
- AstraZeneca
Asthma, Allergy
Comparing Allergenic Effects of 3 German Cockroach Extracts in Adults
The purpose of this study is to test and compare the allergenic effects of three commercially available German cockroach allergen extracts in adults.
- Trial name
- NCT00132847
- Testing
- German Cockroach Allergen extract
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diabetes, Heart Failure
Avoidable Hospitalizations/ Emergency Department Visits- Systematic Review and Meta-synthesis of Qualitative Research
The aim of the study is to synthesize qualitative evidence related to preventable hospitalizations/ emergency department visits from the perspectives of patients, their families/caregivers, health care providers, and…
- Conditions
- Diabetes, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT05456906
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University
Asthma, Lung Diseases
Isocyanate Dermal Exposures in Autobody Shops
To characterize the skin route of exposure to the allergen hexamethylene diisocyanate (HDI) in the auto body industry.
- Trial name
- NCT00005552
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Intubation Complication, Asthma
Predicting Intubation of Patients Hospitalised for Acutely Attacked Asthma
Although the asthmatic treatments currently be effective in term of efficacy of inhaled medications and good clinical outcome including symptom controlled and asthma exacerbation number, the large number of worse event still have…
- Trial name
- NCT04277078
- Where
- Thailand
- Volunteers
- 509 people
- Sponsor
- Hat Yai Medical Education Center
Asthma
Evaluation of Dupilumab in Patients With Severe Steroid Dependent Asthma
Primary Objective: To evaluate the efficacy of dupilumab, compared with placebo, for reducing the use of maintenance oral corticosteroids (OCS) in participants with severe steroid-dependent asthma.
- Trial name
- VENTURE (NCT02528214)
- Testing
- Dupilumab, Oral corticosteroid therapy (prednisone/prednisolone), Inhaled corticosteroid (ICS) therapy
- Where
- 80 sites in United States, Argentina and 15 more
- Volunteers
- 210 people
- Sponsor
- Sanofi
Asthma
Study on Foster Efficacy Maintenance and Reliever vs Foster Maintenance + Salbutamol Reliever in Asthmatics (MART2)
Primary objective: The primary objective of the study was to compare the efficacy of Maintenance and Reliever Therapy (MART) with Foster® 100/6 μg (one inhalation bid) plus additional inhalations as needed, with the standard…
- Trial name
- NCT00861926
- Testing
- Salbutamol, Beclomethasone dipropionate + Formoterol
- Where
- 206 sites in Bulgaria, Croatia and 12 more
- Volunteers
- 1,714 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma
Effects of Omalizumab Compared to Non-Omalizumab Treatment in Asthma Patients
The purpose of this study is effects of Omalizumab compared to non-Omalizumab treatment in the propensity-matched group on asthma exacerbation in asthma patients in Korea: a retrospective cohort in real world.
- Trial name
- NCT02921178
- Testing
- Omalizumab
- Volunteers
- 124 people
- Sponsor
- Ajou University School of Medicine
Asthma, Lung Diseases
Predictors of Hospital-Based Care in Asthma
To identify clinical predictors of episodes of hospital-based care in people with asthma.
- Trial name
- NCT00005484
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Heart Disease (CHD), Heart Failure
Community Exercise Treating Effect on Cardiopulmonary Disease Patients
The goal of this clinical trial is to learn if community-based exercise training can benefit patients aged 18 to 85 with diminished cardiovascular and pulmonary function.
- Conditions
- Coronary Heart Disease (CHD), Heart Failure, Cardiomyopathy, COPD
- Trial name
- NCT07154355
- Testing
- community-based exercise training
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Guangdong Provincial People's Hospital
Mild to Moderate Asthma
A Study of CDX-622 in Participants With Mild to Moderate Asthma
This is a study to determine the safety, pharmacodynamics (PD), and pharmacokinetics (PK) of CDX-622 in adults with mild to moderate asthma.
- Trial name
- NCT07330778
- Testing
- CDX-622
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- Celldex Therapeutics
Asthma
Study Evaluating the Safety and Efficacy of MN-221 as an Adjunct to Standard Therapy in Subjects Experiencing an Acute Exacerbation of Asthma
The objective of this clinical study is to examine the safety and effectiveness of intravenous MN-221 compared to placebo when administered as an adjunct to standard therapy in subjects experiencing an acute exacerbation of…
- Trial name
- NCT00838591
- Testing
- MN-221
- Where
- 15 sites in United States
- Volunteers
- 176 people
- Sponsor
- MediciNova
Difficult Asthma, Severe Persistent Asthma
Prevalence of Hyperventilation Syndrome in Difficult Asthma
Most of asthmatics patients remain uncontrolled despite an inhaled steroids treatment. Chronic hyperventilation syndrome (also called Idiopathic Hyperventilation) occurs in 20 to 40% of asthmatic patients.
- Conditions
- Difficult Asthma, Severe Persistent Asthma, Hyperventilation Syndrome
- Trial name
- PRESH (NCT01862289)
- Testing
- Diagnostic of chronic hyperventilation syndrome
- Where
- France
- Volunteers
- 151 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma in Children
Integrating Deep Learning CT-scan Model, Biological and Clinical Variables to Predict Severity of Asthma in Children
Artificial intelligence (AI) offers substantial opportunities for healthcare, supporting better diagnosis, treatment, prevention and personalized care.
- Trial name
- BREATHE (NCT05140889)
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Asthma
BI 671800 ED in Steroid-naive Asthmatic Patients
This is a 6 week study to investigate the effectiveness and safety of BI 671800 ED in patients with asthma who do not take inhaled corticosteroids.
- Trial name
- NCT01092143
- Testing
- BI 671800, Fluticasone propionate
- Where
- 92 sites in United States, Australia and 8 more
- Volunteers
- 389 people
- Sponsor
- Boehringer Ingelheim
Asthma
Applying Interactive Mobile Health to Asthma Care in Teens (AIM2ACT)
The aims of this application are to develop and test AIM2ACT, a mobile health (mHealth) tool, delivered via smartphones, that fosters helpful caregiver support as early adolescents (ages 12-15) with persistent asthma develop and…
- Trial name
- AIM2ACT (NCT02302040)
- Testing
- AIM2ACT, Self-guided
- Where
- 2 sites in United States
- Volunteers
- 92 people
- Sponsor
- University of Florida
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