Clinical trials: BRONCHIAL ASTHMA
Allergy
Dust Mite Allergen Reduction Study
This study will determine whether use of an in-home test kit results in decreased dust mite allergen levels in homes of children who are sensitive or allergic to dust mites.
- Trial name
- NCT00339690
- Testing
- MITE-T-FASTtest kit
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Cardiovascular Diseases, Coronary Disease
Honolulu Heart Program
To investigate coronary heart disease and stroke among American men of Japanese ancestry who were living on the island of Oahu in 1965. Morbidity and mortality surveillance of the original cohort is continuing.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Cerebrovascular Accident, Heart Diseases
- Trial name
- NCT00005123
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma
Comparison of Budesonide and Formoterol Absorption From Budesonide/Formoterol Easyhaler and Symbicort Turbuhaler
The purpose of this study is to compare the test product Budesonide/formoterol Easyhaler with the marketed product Symbicort Turbuhaler in terms of the drug absorbed into the bloodstream.
- Trial name
- NCT01386996
- Testing
- Budesonide/formoterol Easyhaler 320/9 microg, Symbicort Turbuhaler forte
- Where
- Finland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Orion Corporation, Orion Pharma
Asthma
Assessment of the Safety, Efficacy, PK, and Extrapulmonary Pharmacodynamics (PD) of Albuterol Sulfate Pressurized Inhalation Suspension (Hereafter Referred to as AS MDI) Compared to Proventil as an Active Control in Subjects With Asthma
This is a randomized, cumulative dose, open-label, 2-period crossover, multi-center study to assess the safety, efficacy, PK, and extrapulmonary PD of cumulative doses of AS MDI compared to cumulative doses of Proventil as an…
- Trial name
- NCT03371459
- Testing
- AS MDI, Proventil
- Where
- 5 sites in United States
- Volunteers
- 46 people
- Sponsor
- AstraZeneca
Asthma
Tezepelumab PRO Study
This study assesses the impact of tezepelumab treatment not only on asthma control but also on cough specific Health-Related Quality of Life (HRQoL). Asthma control can be evaluated using Asthma Control Questionnaire (ACQ).
- Trial name
- TezepelumabPRO (NCT05922891)
- Where
- 29 sites in Japan
- Volunteers
- 92 people
- Sponsor
- AstraZeneca
Bronchospasm, Activity/Exercise Induced Bronchospasm
A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise
During this study, your child will need to attend up to 5 office visits and maintain regular telephone contact with the clinic. Certain office visits will include physical exams, medical history review, exercise challenge test…
- Trial name
- NCT00118690
- Testing
- Fluticasone propionate/salmeterol
- Where
- 51 sites in United States
- Volunteers
- 227 people
- Sponsor
- GlaxoSmithKline
Asthma, Allergic Rhinitis
Genetics of the Early and Late Response to Allergen Challenge
The investigators are investigating the early and late responses to allergen challenge. The research participants who the investigators will study (from three cohorts) will be part of independently-approved studies involving…
- Trial name
- NCT01113697
- Where
- 5 sites in Canada
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma
MK0476 Study in Adult Patients With Acute Asthma (0476-322)
This study evaluates the efficacy and safety of MK0476 intravenous administration in adult patients with acute asthma.
- Trial name
- NCT00229970
- Testing
- montelukast sodium
- Volunteers
- 225 people
- Sponsor
- Organon and Co
Asthma in Children, Asthma Attack
Child Asthma : What Parents Attitude During an Asthma Attack at Home Before Consulting the Pediatric Emergencies
prospective multicenter observational study. Parents whose children meet the inclusion criteria complete a questionnaire assessing the child's follow-up, the management of the current asthma attack, and the treatment provided at…
- Conditions
- Asthma in Children, Asthma Attack, Therapeutic Adherence
- Trial name
- ASPECT (NCT03967873)
- Where
- 2 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Brest
Asthma
Development of Small Airway Disease Questionnaire
The aim of this study is to develop a patient reported outcome tool specific to small airways disease, which assesses symptoms and signs of small airways disease and may help in addition to FEF50% to discriminate between…
- Trial name
- SADQ (NCT01360294)
- Where
- Netherlands
- Volunteers
- 65 people
- Sponsor
- University Medical Center Groningen
Sleep Apnea, Allergic Rhinitis
Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR Study
It has been demonstrated that allergic rhinitis (AR) reduces sleep quality by some components such as nasal obstruction. Pollution and allergen exposure worsening AR, sleep quality is deteriorated.
- Conditions
- Sleep Apnea, Allergic Rhinitis, Allergic Asthma, Pollution Exposure
- Trial name
- POLLAR (NCT03776773)
- Testing
- Pollution exposure
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Asthma, Asthma Attack
ASTHMAXcel Emergency Department Study
This protocol focuses on Phase 1 of a planned two-phase research project. Phase 1 aims to test and adapt a prototype ASTHMAXcelED application for the ED.
- Trial name
- ASTHMAXcel (NCT05013073)
- Testing
- ASTHMAXcel ED Application
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Montefiore Medical Center
Asthma
A Study of Lebrikizumab in Participants With Uncontrolled Asthma on Inhaled Corticosteroids and a Second Controller Medication
This randomized, multicenter, double-blind, placebo-controlled, parallel-group study will evaluate the efficacy and safety of lebrikizumab in participants with asthma whose disease remains uncontrolled despite daily treatment…
- Trial name
- NCT01868061
- Testing
- Lebrikizumab
- Where
- 232 sites in United States, Argentina and 24 more
- Volunteers
- 1,068 people
- Sponsor
- Hoffmann-La Roche
Asthma in Children
Evaluation of the Asthma Management Program to Promote Activity for Students in Schools (Asthma-PASS)
Physical activity (PA) is an important component of asthma management in children. Studies show that PA is associated with decreased severity of asthma symptoms, as well as improved disease control and quality of life.
- Trial name
- NCT04576442
- Testing
- Asthma-PASS, Basic Asthma Management (AM), Child/Caregiver Education session
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- Montefiore Medical Center
Bronchiolitis
The Bronchiolitis in Hospitalized Infants Study
The goal of this clinical trial is to determine whether it is possible to identify, enroll, and deliver the study intervention (the corticosteroid dexamethasone) in hospitalized infants with bronchiolitis.
- Trial name
- BroncHI (NCT05994183)
- Testing
- Dexamethasone Oral
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- IDeA States Pediatric Clinical Trials Network
Asthma
Environmental Control as Add-on Therapy in Childhood Asthma
This study evaluates the effects of adding on an environmental home intervention to standard asthma medication management on controller medication requirements among children and adolescents with asthma.
- Trial name
- ECATCh (NCT02251379)
- Testing
- Flovent Diskus, Home Environmental Intervention, Advair Diskus
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Johns Hopkins University
Asthma, COPD
Chronic Obstructive Pulmonary Disease and Asthma in Workers at Navanakorn Industrial Zone, Thailand
The goal of this observational study is to determine the prevalence of asthma and chronic obstructive pulmonary disease (COPD) among workers in an industrial zone in Thailand.
- Trial name
- NCT07383896
- Testing
- Pulmonary function test
- Where
- Thailand
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Asthma in Children
The Effectiveness and Safety of Dupilumab in Children with Asthma in China: a Real-world Study
Observe the changes of type II inflammation markers, lung function, and symptom scores in asthmatic patients aged 6 to 14 during the use of dupilumab to analyze its efficacy.
- Trial name
- NCT06851403
- Testing
- Dupilumab
- Where
- China
- Volunteers
- 213 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Safety of Long Acting Beta Agnoists
Effect of Gly16Arg Polymorphism in ADRB2 Gene on Asthma Control in Children Receiving Long Acting Beta Agonists
Asthma is the most common chronic disease of childhood affecting 6.2 million children between 2 and 18 years of age, and is the most common cause of school absenteeism due to chronic disease.
- Trial name
- NCT01108627
- Testing
- open-labeled inhaled corticosteroids (ICS); FORADIL® AEROLIZER®, foradil
- Sponsor
- Nemours Children's Clinic
Asthma
Pilot Study of RNS60 in Allergen-induced Bronchoconstriction
This study evaluates the use of RNS60 in the treatment of asthma examining regional improvements in inflammation using PET imaging. All subjects will be treated with both RNS60 and placebo in a crossover design.
- Trial name
- NCT02497222
- Testing
- RNS60, Normal Saline
- Where
- United States
- Sponsor
- Revalesio Corporation
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