Clinical trials: Back Pain, Low
Chronic Low Back Pain
Rage Against the Pain to Address Chronic Low Back Pain Among Veterans
Chronic low back pain is a leading cause of disability among Veterans. Yoga is recommended as a front-line treatment option for chronic low back pain and is available across the VA healthcare system; however, despite yoga being…
- Trial name
- RAP (NCT05103475)
- Testing
- Rage Against the Pain (RAP), Control
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Chronic Low Back Pain
Comparison of Kinesio Taping and Local Injection in Chronic Low Back Pain
Low back pain can be seen in every period of life. More than 80 percent of the society complain of low back pain at any time of life.
- Trial name
- NCT03895307
- Testing
- kinesio tape, local anesthetic, local serum physiologic
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Low Back Pain, Recurrent, Healthy
Effects of Sleep Disruption on Drug Response
The central scientific premise of the proposed study is that sleep disruption (SD) will influence individuals' subjective response to blinded medication administration.
- Trial name
- NCT03680287
- Testing
- Within-Subject test of blinded study medication
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Low Back Pain
Comparison of Extensible and Inextensible Lumbosacral Orthoses for Lower Back Pain
This study is designed to discern if the use of a lumbosacral orthesis (LSO, also call a back support) improves the short-term outcome of lower back pain.
- Trial name
- LSO LBP (NCT01933399)
- Testing
- Inextensible LSO (stiff back support), Extensible LSO, a back support that is flexible, Standard of Care
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Medical University of South Carolina
Low Back Pain, Pain
D-cycloserine in the Management of Chronic Low Back Pain
Pre-clinical studies in rats suggest that D-cycloserine (DCS) is effective in the management of chronic neuropathic pain. This pilot study will attempt to determine the effect of D-cycloserine in the treatment of chronic low back…
- Trial name
- NCT00125528
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Thomas J. Schnitzer
Back Pain Lower Back Chronic
Efficacy of Foot Orthotics in Veterans With Chronic Lower Back Pain
A randomized sham controlled trial evaluating the efficacy of the use of custom foot orthotics in veterans suffering from chronic lower back pain.
- Trial name
- NCT01865539
- Testing
- Custom Foot Orthotic
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Canandaigua VA Medical Center
Lower Back Pain
Placebo-controlled Trial of Transdiscal Radiofrequency Annuloplasty
Each patient was assigned to one of the two groups: IDB or Sham. On the day of the procedure, an IV was inserted in pre-procedural area and patient transported to the procedure room.
- Trial name
- NCT00750191
- Testing
- The Transdiscal Radiofrequency Annuloplasty
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Baylis Medical Company
Chronic Low Back Pain, Sacroiliitis
Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint
This prospective study will be quantitatively analyzing the effectiveness of platelet-rich-plasma (PRP) injections into the sacroiliac (SI) joint in relieving sacroiliitis and low back pain originating from the SI joint.
- Conditions
- Chronic Low Back Pain, Sacroiliitis, Sacroiliac; Backache, Platelet Rich Plasma
- Trial name
- NCT03122119
- Testing
- Platelet Rich Plasma Joint Injection
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Star Spine and Sport
Low Back Pain, Back Pain
Trial of Inserting Prevalence Information Into Lumbar Spine Imaging Reports
The overall goal of the Lumbar Image Reporting with Epidemiology (LIRE) is to perform a large, pragmatic, cluster randomized controlled trial to determine the effectiveness of a simple, inexpensive and easy to deploy intervention…
- Conditions
- Low Back Pain, Back Pain, Lumbar Pain, Backache
- Trial name
- LIRE (NCT02015455)
- Testing
- Epidemiologic benchmarks included in lumbar imaging reports
- Where
- 4 sites in United States
- Volunteers
- 250,401 people
- Sponsor
- University of Washington
Low Back Pain
Efficacy and Safety of Lymphdiaral Basistropfen (HDC) in the Treatment of Chronic Low-back Pain
To evaluate superiority of HDC in comparison to placebo in the treatment of chronic low-back pain in relation to pain, functional impairment, quality of life, and state of health during a 15-week treatment period.
- Trial name
- 144 (NCT01049373)
- Testing
- HDC
- Where
- Germany
- Volunteers
- 221 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Low Back Pain
TissueLink Study During Multi-Level Spine Surgery
The overall objective of the investigators research is to test the clinical efficacy of the TissueLink™ (Salient Surgical Technologies, Inc.) coagulation system in minimizing hemoglobin loss intraoperatively.
- Trial name
- NCT01300559
- Testing
- Tissuelink device
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Mechanical Low Back Pain, Chronic Low Back Pain
Spinal Control During Functional Activities to Improve Low Back Pain Outcomes
Exercise is one of the primary interventions used with people with chronic, mechanical low back pain. It is unknown, however, which exercise is best for which person, which exercises a person will adhere to and for how long, and…
- Trial name
- LBP (NCT02027623)
- Testing
- Motor skill training, Strength and flexibility exercise
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Washington University School of Medicine
Low Back Pain
Spinal Manipulation Services vs. Prescription Drug Therapy for Long-term Care
Our overall objective is to assess the value of Spinal Manipulation Services as compared to Prescription Drug Therapy for long-term management of chronic Law back Pain (LBP).
- Trial name
- NCT03669354
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Southern California University of Health Sciences
Low Back Pain
Diazepam Use With Standard Management for Acute Low Back Pain
Given the poor pain and functional outcomes that persist beyond an Emergency Department (ED) visit for musculoskeletal low back pain (LBP), we propose a clinical trial to evaluate whether combining a benzodiazepine with an NSAID…
- Trial name
- NCT02646124
- Testing
- Naproxen, Diazepam
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Montefiore Medical Center
Low Back Pain
Investigation of Trunk Muscle Size and Function in Older Adults With Chronic Low Back Pain
Rehabilitative Ultrasound Imaging (US) is a procedure used to evaluate skeletal muscle size and function to inform clinical practice. US has been shown to be a reliable and valid tool for measuring changes in trunk muscle (i.e.
- Trial name
- NCT01221233
- Testing
- Neuromuscular Electrical Stimulation, Moist Heat
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Delaware
Low Back Pain, Recurrent
Treatment of Veterans With Chronic Low Back Pain
The purpose of this study is to assess the effectiveness of hypnosis in the treatment of chronic low back pain.
- Trial name
- CLBP (NCT00361270)
- Testing
- Hyp-8, Hyp-2 w recordings, Hyp-8 w recordings
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- VA Office of Research and Development
Chronic Pain, Back Pain
Hippocampal Stimulation in Chronic Low Back Pain
In this study the investigators aim to examine the effects of Transcranial Magnetic Stimulation (TMS) on hippocampal network connectivity and pain levels in individuals with chronic low back pain.
- Conditions
- Chronic Pain, Back Pain, Pain
- Trial name
- NCT04888494
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northwestern University
Low Back Pain
Study of Low Level Laser Therapy to Treat Low Back Pain
The purpose of this study is to determine whether the Erchonia® ML Scanner (MLS) is effective in the treatment of acute minor episodic chronic low back pain of musculoskeletal origin.
- Trial name
- NCT01835756
- Testing
- Erchonia MLS
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Erchonia Corporation
Low Back Pain
Long Term Safety Study of Tanezumab in Chronic Low Back Pain
The purpose of this study is to investigate the safety and efficacy of tanezumab for chronic low back pain. Patients who were randomized and treated with study medication in a previous chronic low back pain "parent" study will be…
- Trial name
- NCT00924664
- Testing
- Tanezumab 20 mg, Tanezumab 10 mg
- Where
- 149 sites in United States
- Volunteers
- 849 people
- Sponsor
- Pfizer
Chronic Low-back Pain, Chronic Pain
Digital Clinical Hypnosis for Chronic Pain Management
This ClinicalTrials.gov posting contains two randomized controlled trials. The study procedures were identical, except Study 1 was funded by NIH and enrolled adults with chronic low back pain, whereas Study 2 was funded by the UW…
- Trial name
- NCT06050083
- Testing
- Hypnosis audio recordings
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington