Clinical trials: Back Pain
Chronic Low Back Pain (CLBP), Physical Therapy
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
The purpose of this research study is to investigate whether a single administration of psilocybin can improve interoceptive awareness (awareness of bodily sensations) in individuals with chronic low back pain undergoing physical…
- Conditions
- Chronic Low Back Pain (CLBP), Physical Therapy, Psilocybin
- Trial name
- NCT07306364
- Testing
- Psilocybin 10 mg, Psilocybin 25 mg, Niacin 100 mg
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yale University
Low Back Pain
The Role of Lumbar Multifidus Characteristics in the Development of Low Back Pain
Low back pain (LBP) is a severe epidemic in the world. Despite its high prevalence, 90% of the cases have no identifiable cause.
- Trial name
- NCT03387930
- Where
- Hong Kong
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Low Back Pain
The Oxford Pain, Activity and Lifestyle (OPAL) Cohort Study
The OPAL study is about health outcomes in older adults. The investigators are surveying 4,000 adults across England to see how health and physical activity change over time.
- Trial name
- OPAL (NCT02820571)
- Where
- United Kingdom
- Volunteers
- 5,409 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Acute Low Back Pain
The Palliative Effect of TENS-WAA on 'Capsaicin/Heat' Induced Acute Lower Back Pain: a Self-controlled Clinical Study
Acute lower back pain is a common condition that occurs in all age groups, and most people will experience acute lower back pain at least once in their lives.
- Trial name
- NCT06944665
- Testing
- Transcutaneous Electrical Nerve Stimulation based on Wrist-Ankle Acupuncture theory
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xiaonan Huang
Chronic Low Back Pain
Chronic Low Back Pain Randomized Controlled Trial
Chronic low back pain is a common condition that can negatively impact quality of life and that lacks highly effective treatment options.
- Trial name
- NCT02286232
- Testing
- Stretching exercise, Self-care book
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Stamford Hospital
Chronic Pain
Optimal Stimulation Programming for Spinal Peripheral Neuromodulation
To determine the best parameters with various leads to cover back and leg pain and provide best pain relief
- Trial name
- NCT02346383
- Testing
- preset program
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Carolinas Center for Advanced Management of Pain
Low Back Pain
Clinical Trial to Compare the Pharmacokinetics and Safety of Eperisone HCl SR Tablet 75mg and Myonal Tablet 50mg
The purpose of this study is to Evaluate and Compare Safety and Pharmacokinetic of the Eperisone HCl SR and Myonal in healthy Korean male adults.
- Trial name
- NCT01775566
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- NVP Healthcare
Low Back Pain
Multi-Omics Characterization of Percutaneous Electrolysis in Low Back Pain
Low back pain is a highly prevalent musculoskeletal condition and is frequently associated with structural and functional alterations of the lumbar multifidus muscle.
- Trial name
- MOPE-LBP (NCT07524010)
- Testing
- Percutaneous electrolysis
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Back Pain
Characteristics of Back Pain Callers
Back pain is experienced by approximately 80% of the population during their life. However, only a small minority (<1%) will have a medical condition (such as Cauda Equina Syndrome) which requires immediate medical intervention.
- Trial name
- NCT03474068
- Volunteers
- 7,120 people, healthy volunteers welcome
- Sponsor
- Teesside University
Lumbar Radicular Pain, Spinal
Cutaneous Silent Period-Based Comparison of DRG-PRF and TFESI in Lumbar Radicular Pain
This prospective clinical study compares the effects of two interventional treatments, dorsal root ganglion pulsed radiofrequency (DRG-PRF) and transforaminal epidural steroid injection (TFESI), on patients with lumbar radicular…
- Conditions
- Lumbar Radicular Pain, Spinal, Inhibition
- Trial name
- CSP-LRP (NCT07097532)
- Testing
- Radiofrequency, Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- ahmet başarı
Chronic Low Back Pain (CLBP), Chronic Neck Pain
Comparative Analysis of Heart Rate Variability in Patients with Cervical Pain, Lumbar Pain, and Healthy Controls
This is a cross-sectional study designed to evaluate potential differences in heart rate variability (HRV) indices based on the affected body region (cervical vs lumbar) in individuals with chronic pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Neck Pain, Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06890793
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Dysmenorrhea, Back Pain Lower Back
Effect of Shockwave Therapy on Low Back Pain in Primary Dysmenorrhea
Primary dysmenorrhea (PD), defined as menstrual pain without any structural lesions, usually begins shortly before or immediately after the onset of the menstrual cycle and commonly lasts for 48 to 72 hour
- Trial name
- NCT06762106
- Testing
- shockwave therapy, hot back
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Deraya University
Low Back Pain, Sacroiliac Disorder
The Influence of the Manipulation of the Sacroiliac Joint on Low Back Pain
The primary focus of this study is to know the influence of sacroiliac joint manipulation on low back pain with or without radiation to lower limbs, in the lumbopelvic-hip joint
- Trial name
- NCT03794830
- Testing
- manipulation group (MG), electrotheraphy group (EG)
- Where
- Spain
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Osteopathic Manipulation, Low Back Pain
The Effects of OMT on the Expression Patterns of Immune Cell Biomarkers
This study intends to understand the effects of osteopathic manipulative treatment (OMT) on the expression patterns of 60 immune cell biomarkers in the peripheral blood mononuclear cells (PBMC) of each participant, before and…
- Conditions
- Osteopathic Manipulation, Low Back Pain, Biomarkers
- Trial name
- NCT03250312
- Testing
- The Osteopathic Manipulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- A.T. Still University of Health Sciences
Low Back Pain
The Effect Water-exercise on Low Back Pain and Sick Leave, Among Healthy Pregnant Women
To investigate the possible effect of an unsupervised water-exercise program, on the intensity of low back pain and the number of days spent on sick leave, among healthy pregnant women Our hypothesis is, that 45 minutes of water…
- Trial name
- WAPW (NCT02354430)
- Testing
- Water-exercise
- Where
- Denmark
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Non-specific Chronic Low Back Pain
Relationships Between Muscle Activity, Soft Tissue Changes, and Movement Strategies in Individuals With Chronic Low Back Pain
This study aims to explore, in patients with chronic non-specific low back pain (cnsLBP), the relationships between lumbar muscle activity, structural and morphological characteristics of the paraspinal muscles, and movement…
- Trial name
- E-LBP (NCT07806253)
- Testing
- Supervised Progressive Walking Test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Disc Degenerative Disease, Spine Degeneration
Physiotherapy and Osteopathic Treatment for Pain in the Cervical and Lumbar Spine and Temporomandibular Joints
Study Summary: Effectiveness of Physiotherapy and Osteopathy in Treating Spinal and Temporomandibular Joint Pain About the Study and Its Objective This study is conducted by Artur Hołodniuk, MSc, a physiotherapist and academic…
- Conditions
- Disc Degenerative Disease, Spine Degeneration, Back Ache, Temporomandibular Disorder (TMD)
- Trial name
- NCT07830836
- Testing
- General Osteopathic Treatment, Visceral Therapy, Magnetic field therapy
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Sacroiliac Strain, Low Back Pain
Correction of Low Back Pain From Sacroiliac Malrotation With a Simple in Home Exercise
60 participants with low back pain will be examined to determine the direction and extent of sacroiliac malrotation. If malrotation exists, they will be randomized to 3 treatment groups: 1 will be taught how to use their thigh to…
- Trial name
- SIbackpain (NCT03888235)
- Testing
- Immediate corrective exercises, Immediate use of pelvic support belt, Delayed treatment
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Low Back Pain
Unraveling Back Pain Chronicity: an EMG and EEG Study
This study aims at examining the influence of both threat of experimentally induced pain and clinical low back pain (LBP) on trunk motor control on the one hand and brain activity related to movement preparation on the other…
- Trial name
- NCT03705676
- Testing
- Rapid Arm Movements, Unpleasant stimulus, Vibrotactile stimulus
- Where
- Belgium
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Ghent