Clinical trials: Back Pain
Failed Back Surgery Syndrome, Pain
Spinal Cord Stimulation With Precision® System Versus Reoperation for Failed Back Surgery Syndrome
The EVIDENCE trial is a randomized controlled trial comparing the therapeutic effectiveness and cost-effectiveness of the Precision® Spinal Cord Stimulation with that of reoperation as a treatment of pain in patients with Failed…
- Conditions
- Failed Back Surgery Syndrome, Pain, Back Pain
- Trial name
- Evidence (NCT01036529)
- Testing
- Precision Spinal Cord Stimulator, Back Surgery
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Chronic Low Back Pain, Degenerative Disc Disease
Intra-discal Injection of Platelet-rich Plasma (PRP) Enriched With Exosomes in Chronic Low Back Pain
Intervertebral disc pathology accounts for 40% or more cases of chronic LBP. Available treatment options do not improve the underlying degenerative condition hence This indicates the need for new therapies.
- Trial name
- NCT04849429
- Testing
- Platelet rich plasma (PRP) with exosomes, Normal Saline
- Where
- 2 sites in India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Himanshu Bansal Foundation
Chronic Low Back Pain (CLBP), Chronic Neck Pain
Comparative Analysis of Heart Rate Variability in Patients with Cervical Pain, Lumbar Pain, and Healthy Controls
This is a cross-sectional study designed to evaluate potential differences in heart rate variability (HRV) indices based on the affected body region (cervical vs lumbar) in individuals with chronic pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Neck Pain, Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06890793
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Adolescent Behavior
Changes in Sagittal Spine Posture and Flexibility on Adolescents
Several research show a high prevalence of spinal misalignments and a lack of stability of the spine in the adolescent population.
- Trial name
- NCT03831867
- Testing
- Pilates
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Low Back Pain
Kinesiotape and Core Exercises in Federated Boxers
Introduction. Nonspecific lumbar pain is a very common cause of sports decline in boxers, possibly due to the repetitive movements of flexion and rotation in their sport, so the investigators believe it is interesting to seek an…
- Trial name
- NCT03865784
- Testing
- Experimental, Control
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Low Back Pain, Nerve Entrapment Syndrome
Ultrasound Localization and Guided Injection for Superior Cluneal Nerve Entrapment
Low back pain (LBP) is a common complaint in the clinical setting. Among all the differential diagnosis for LBP, superior cluneal nerve (SCN) entrapment is the commonly omitted one.
- Trial name
- NCT04478344
- Testing
- Ultrasound guided hydrodissection of superior cluneal nerve
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Low Back Pain
Evaluating Acupuncture Relationship With the Catecholaminergic Pathway
Activation of the sympathetic nervous system attenuates inflammation via catecholamines, recent advances in electroacupuncture allow activating critical neuronal networks with the release of catecholamines the aim of this…
- Trial name
- NCT02876432
- Testing
- Electroacupuncture, Diclofenac sodium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Chronic Low-back Pain
The ECEALT Chronic Low Back Pain Study
The primary objective of this double-blind randomized control trial (RCT) is to evaluate the clinical effectiveness of LLLT as adjunctive therapy to standard exercise treatment in patients with non-specific chronic LBP.
- Trial name
- NCT05040633
- Testing
- BTL 4110 Smart Laser Therapy Equipment (BTL Industries Ltd, United Kingdom (UK)), Standard Exercise Therapy
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Health Rehab and Research Clinic
Communication, Back Pain
Ideas, Concerns, Expectations. Implementing Patient-centered Communication
Exploring patients' ideas, concerns and expectation (ICE) is a communication tool to promote patient centredness and shared decision making during a consultation.
- Trial name
- ICE (NCT03711071)
- Testing
- Workshop "ICE training"
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Low Back Pain, Disc Disease
Fibrin for Chronic Multi-level Discogenic Low Back Pain
Intra-annular injections of non-autologous fibrin for moderate to severe chronic low back pain (LBP).
- Conditions
- Low Back Pain, Disc Disease, Disc Degeneration, Radiculopathy
- Trial name
- NCT04621799
- Testing
- Fibrin sealant
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Pauza, Kevin, MD
Low Back Pain
Study of Cells From Spinal Cavity of Patients With Low Back Pain
The purpose of this study to determine if cells collected give us information about what is causing a patient pain can be detected and connected with epiduroscopy images (pictures taken with a small fiber optic scope).
- Trial name
- NCT01089491
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Low Back Pain
Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion
The purpose of this project is to study the effects of preoperative followed by scheduled intravenous acetaminophen on pain control for 24 hours postoperatively after minimally invasive 1 or 2 level transforaminal lumbar…
- Trial name
- NCT02061774
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Chronic Low Back Pain (CLBP)
Effects of Repetitive Transcranial Magnetic Stimulation on Pain Thresholds in Patients With Chronic Low Back Pain
Chronic low back pain (CLBP) is a common reason for which patients are treated with opioids. Because the misuse of prescription opioids has become a serious problem in the Uinted States, finding effective alternative…
- Trial name
- NCT03973788
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Low Back Pain
Acupuncture Analgesia in Relation to Psychiatric Comorbidity
It is our hypothesis that patient's expectations concerning treatment outcome will be influenced by their psychiatric symptoms, and that this expectancy will have a strong influence on the efficacy of acupuncture treatment to…
- Trial name
- LBP (NCT00307788)
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Back Pain, Coronary Artery Disease
Detecting and Addressing Preclinical Disability
The Physical Functioning Inventory (PFI) is a standardized patient reported outcome measure that assesses preclinical disability.
- Conditions
- Back Pain, Coronary Artery Disease, Chronic Obstructive Pulmonary Disease, Diabetes
- Trial name
- NCT01979081
- Testing
- Tailored advice from a physiotherapist and/or an occupational therapist through the myOSCAR patient portal
- Where
- Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- McMaster University
Disc Degeneration
Lumbar Spine on MRI and Low Back Pain in Elite Cross-country Skiers
The investigators will examine the prevalence of low-back pain and disc degeneration among Finnish elite skiers between 16 and 35 years of age and compare these findings with the data collected among healthy volunteers studied…
- Trial name
- NCT05641857
- Where
- Finland
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Orton Orthopaedic Hospital
Low Back Pain
A Study of a Potential Mechanisms of Spinal Manipulation in the Treatment of Low Back Pain
The purpose of this study was to determine the immediate effect of 3 common physical therapy interventions for people experiencing low back pain on the perception of thermal pain.
- Trial name
- NCT00922220
- Testing
- stationary bike, lumbar extension exercise, spinal manipulative therapy
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Florida
Low Back Pain
Group Hydrotherapy Treatment for Athletes With Lower Back Pain
The effect of group hydrotherapy on chronic low back pain and function among athletes will be examined.
- Trial name
- NCT06894355
- Testing
- hydrotherapy, control group
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gali Dar
Chronic Low-Back Pain, Refractory Pain
Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
The objective of this study is to evaluate the efficacy of BurstDR dorsal column stimulation, compared with conventional medical management, in improving pain and back-related physical function in subjects suffering with chronic…
- Conditions
- Chronic Low-Back Pain, Refractory Pain, Neuropathic Pain
- Trial name
- NCT04479787
- Testing
- Spinal Cord Stimulation, Conventional Medical Management
- Where
- 30 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Chronic Pain
Pain, Nutrition and Glycemic Response in Chronic Low Back Pain and Breast Cancer Survivors
The development of chronic pain is one of the most seen sequelae in the cancer survivor population. Literature reports the presence of pain in approximately 40% of 5-year survivors.
- Trial name
- NCT04459104
- Testing
- Low glycemic load, High glycemic load
- Where
- 2 sites in Belgium
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel