Clinical trials: Back Pain Lower Back
Inflammation, Fascia; Inflammation
The Acute Impact of Yoga-based Stretching on Inflammation and Its Resolution
The goal of this study is to explore the impact of two types of yoga-based body stretching (mild and intense) on dynamic changes of Systemic Inflammatory Cytokines (SICs) and Specialized Pro-resolving Mediators (SPMs) in…
- Conditions
- Inflammation, Fascia; Inflammation, Musculoskeletal Pain, Lower Back Pain
- Trial name
- NCT04444102
- Testing
- Yoga-based stretching
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Harvard University Faculty of Medicine
Chronic Low-back Pain
Effect of Connective Tissue Massage in Low Back Pain
Connective tissue massage (CTM) is a manual therapy method that aims to modulate the autonomic response using special stroking techniques performed on connective tissue, and its analgesic effects are described in the literature.
- Trial name
- NCT07462832
- Testing
- Connective tissue massage
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Okan University
Low Back Pain, Neck Pain
The Spine Phenome Project
The goal of this observational trial is to compare the health history and motion capabilities of participants with low back pain disorders to participants with healthy spines. The main question[s] it aims to answer are to: 1.
- Trial name
- NCT05776771
- Where
- United States
- Volunteers
- 10,500 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Low Back Pain, Compare Pain Modulation Assessments in Pain-free Cohorts
Pain Modulation - Experimental Assessments Using Different Modalities
The goal of this study is to investigate how different painful stimuli are processed and modulated in the nervous system. In various pain conditions, including low back pain, often no specific source can be identified as the…
- Trial name
- NCT04323293
- Testing
- Cold Water Bath, Neutral Water Bath
- Where
- Switzerland
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Schweinhardt Petra
Low Back Pain
Rehabilitation of Dynamic Muscle, Back Pain and Postural Balance
Workers in the various branches of the investigators industrial society can be considered as a group susceptible to risks due to the nature of its activities related to the intense demands of their work units with varying degrees…
- Trial name
- RDM (NCT01011270)
- Where
- Brazil
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Universidade Camilo Castelo Branco
Recurrent Low Back Pain, Healthy
Pain Inhibition and Facilitation in Recurrent Low Back Pain
This study evaluates psychophysical measures of pain inhibition and facilitation, along with cortical responses to different sensory stimuli, in patients with recurrent low back pain and matched healthy individuals.
- Trial name
- NCT03463759
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Low Back Pain
Assessment of LTP-like Pain Amplification in Chronic Low Back Pain Patients
The present study is aimed to assess the LTP-like pain amplification in chronic low back pain patients to explore the central and peripheral effect for pain LTP.
- Trial name
- NCT03362827
- Testing
- Chronic low back pain patients, Subjects without chronic low back pain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Low Back Pain, Musculoskeletal Pain
Soft Active Back Exosuit to Reduce Workplace Back Pain
The goal of this clinical trial is to determine if a wearable back exosuit can make it safer and easier for workers who bend, lift, and lower objects in an industrial setting.
- Conditions
- Low Back Pain, Musculoskeletal Pain, Low Back Injury
- Trial name
- NCT05802914
- Testing
- Back Exosuit
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wyss Institute at Harvard University
Low Back Pain
State vs. Trait Alterations in Low Back Pain
The primary goal of this study is to investigate whether different alterations observed in patients with non-specific episodic low back pain (compared to healthy volunteers), detected using several assessments: psychophysical and…
- Trial name
- NCT06412484
- Testing
- Pain Free Session, Low Back Pain Session (= clinically relevant pain), Experimental Pain Session (= clinically irrelevant pain)
- Where
- Switzerland
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Schweinhardt Petra
Low Back Pain
COGNITIVE BEHAVIOURAL THERAPY FOR TREATMENT OF CHRONIC NON-SPECIFIC LOW BACK PAIN
To explore the effect of adding cognitive-behavioral therapy to physical therapy interventions in patients with chronic non-specific back pain.
- Trial name
- NCT04715789
- Testing
- graded exposure and activity
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low Back Pain
Age Bias on Biopsychosocial Factors in Persons With Non-specific Low Back Pain.
Low back pain is a debilitating condition experienced by people of all age groups. This study will be completed in two stages in which back pain assessment tools will be first translated to Urdu language and later on age-related…
- Trial name
- NCT05111782
- Testing
- Symptom Modulation Approach, Movement Control Approach, Functional Optimization Approach
- Where
- Pakistan
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Low Back Pain
The Impact of Epidural Steroid Analgesia on Functional MRI for Patients With LBP
Chronic low back pain (CLBP) is the most prevalent form of chronic pain, and the most common reason for disability in working-age population [2].
- Trial name
- NCT01913782
- Where
- Taiwan
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Low Back Pain
Development and Validation of the Online Patient Satisfaction Index
Low Back Pain (LBP) is the most common musculoskeletal disorder and a leading cause of disability worldwide. It is the most frequent reason for consulting general practice and has an impact on daily life and work capacity.
- Trial name
- NCT03449004
- Testing
- Validation of the OPSI questionnaire
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Low Back Pain, Low Back Pain, Mechanical
Diaphragm Function in Low Back Pain People
Pathomechanism of nonspecific low back pain is not clear for the researchers yet. Our aim is to evaluate the function of one of the stabilizer muscles of the low back area. Diaphragm's postural function is evident.
- Trial name
- LBP_DIA (NCT05486858)
- Testing
- MSK ultrasonograpy, sitting Functional and Lateral Reach Test
- Where
- Hungary
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Szeged University
Low Back Pain, Depression
Subgroups of Older Adults With Back Pain and Multiple Chronic Conditions
The overall goal of this study is to use the National Health and Aging Trends Study (NHATS) data to gain an understanding of how multiple chronic conditions impact the health outcomes of older adults with back pain.
- Conditions
- Low Back Pain, Depression, Anxiety, Osteoarthritis
- Trial name
- NCT03632122
- Where
- United States
- Volunteers
- 8,344 people, healthy volunteers welcome
- Sponsor
- University of Washington
Low Back Pain
Pilot Study to Assess the Efficacy of Botulinum Toxin B on Pain and Disability in Subjects With Acute Low Back Pain
This study will test the hypothesis that Botulinum toxin B (Myobloc®) treatment reduces pain and disability in subjects suffering from acute low back pain due to an identifiable muscle strain or back trauma occurring 3 to 6 weeks…
- Trial name
- NCT00384579
- Testing
- Botulinum toxin B
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Department of Defense
Pain Measurement
Impact on Pain Sensitivity of Clinical Interaction
Pain can currently be quantified using quantitative sensory tests (QSTs). However, we lack knowledge concerning how relational and contextual factors impact these quantitative tests.
- Trial name
- QSTROBOT (NCT04888026)
- Testing
- Quantitative sensory testing
- Where
- 3 sites in Denmark
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Spine Centre of Southern Denmark
Low Back Pain, Spondylolisthesis
Evaluation of Balance Using the Biodex Balance System Among Different Subcategories of Low Back Pain
this study aims to evaluate balance using the biodex balance system among patients with spondylosis, spondylolisthesis, and lumber disc prolapse.
- Conditions
- Low Back Pain, Spondylolisthesis, Spondylosis Lumbar, Balance Assessment
- Trial name
- Biodex (NCT07242976)
- Testing
- Assessment of balance will be measured by The Biodex Balance System (BBS) which computes Postural Stability key indices: the medial-lateral stability index (MLSI), anterior-posterior stability index
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Low Back Pain (CLBP), Heart Rate Variability
Autonomic Differences in Heart Rate Variability Between Healthy and Chronic Low Back Pain Subjects
This study aims to evaluate the autonomic differences in heart rate variability (HRV) between healthy individuals and those with chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06760390
- Where
- Spain
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Low Back Pain
Effects of a Mulligan Mobilisation in the Lumbar Flexion Range of Asymptomatic Subjects
Mulligan's mobilisation techniques are believed to increase the range of movement (ROM) in patients with low back pain. The primary aim of this study was to investigate the mechanical effects of Mulligan's "SNAG" technique on…
- Trial name
- Mulligan (NCT00678093)
- Testing
- Application of the SNAG technique
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Manchester