Clinical trials: Back Pain Lower Back
Failed Back Surgery Syndrome, Complex Regional Pain Syndrome (CRPS)
A Study to Confirm the Safety of High Frequency DRG Stimulator in Patients With Chronic Lower Limb Pain
This study is a prospective, single-arm, open label, single center pilot study to confirm the safety of a ultrahigh frequency DRG stimulator in patients with chronic lower limb pain. The actual trial length is 5 days.
- Trial name
- NCT03285113
- Testing
- GiMer Medical MN 1000 External Stimulator
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- GiMer Medical
Low Back Pain
Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion
The purpose of this project is to study the effects of preoperative followed by scheduled intravenous acetaminophen on pain control for 24 hours postoperatively after minimally invasive 1 or 2 level transforaminal lumbar…
- Trial name
- NCT02061774
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Discogenic Pain
Bone Marrow Concentrate Intradiscal Injection for Chronic Discogenic Low Back Pain
A double-blind, placebo-controlled study to determine the efficacy of intradiscal injection of bone marrow concentrate on discogenic low back pain.
- Trial name
- NCT03340818
- Testing
- Bone Marrow Concentrate
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- APM Spine and Sports Physicians
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Quadratus Lumborum Syndrome
Compare Electrodry Needlig and Dry Needling in Mechanical Low Back Pain
Mechanical low back pain (LBP) generally results from an acute traumatic event, but it may also be caused by cumulative trauma. The severity of an acute traumatic event varies widely, from twisting one's back to being involved in…
- Trial name
- NCT06407687
- Testing
- Electro Dry Needlig, dry needling
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Low Back Pain
Relationship Between Biomarkers and Biomechanical in Nonspecific Low Back Pain
Nonspecific low back pain is one of the most common health problems today. Although it is encountered so frequently, the relationships between the symptoms of patients who complain of low back pain have not been fully explained.
- Trial name
- NCT05503121
- Testing
- 3D motion analysis, muscle activation, biomarker analysis
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Istinye University
Chronic Low-Back Pain, Refractory Pain
Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
The objective of this study is to evaluate the efficacy of BurstDR dorsal column stimulation, compared with conventional medical management, in improving pain and back-related physical function in subjects suffering with chronic…
- Conditions
- Chronic Low-Back Pain, Refractory Pain, Neuropathic Pain
- Trial name
- NCT04479787
- Testing
- Spinal Cord Stimulation, Conventional Medical Management
- Where
- 30 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Low Back Pain
Validation of the French Version of the Fremantle Back Awareness Questionnaire (FreBAQ) in Patients With Chronic Low Back Pain
In patients with chronic low back pain, the Fremantle Back Awareness Questionnaire (FreBAQ) measures the duration and intensity of pain and functional limitations.
- Trial name
- FreBAQ (NCT04931758)
- Testing
- Pain Questionnaire
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Low Back Pain, Recurrent, Healthy
Effects of Sleep Disruption on Drug Response
The central scientific premise of the proposed study is that sleep disruption (SD) will influence individuals' subjective response to blinded medication administration.
- Trial name
- NCT03680287
- Testing
- Within-Subject test of blinded study medication
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Low Back Pain, Neck Pain
Wearable Spine Assessment in Adults With and Without Low Back or Neck Pain
This is a single-site, prospective, observational, single-visit feasibility and validity study. Adult participants with and without low back or neck pain will be screened, consented, and enrolled to undergo a structured…
- Trial name
- AxiSens-01 (NCT07643207)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Ashkan Vaziri
Chronic Low Back Pain (CLBP), Physical Therapy
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
The purpose of this research study is to investigate whether a single administration of psilocybin can improve interoceptive awareness (awareness of bodily sensations) in individuals with chronic low back pain undergoing physical…
- Conditions
- Chronic Low Back Pain (CLBP), Physical Therapy, Psilocybin
- Trial name
- NCT07306364
- Testing
- Psilocybin 10 mg, Psilocybin 25 mg, Niacin 100 mg
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yale University
Mechanical Low Back Pain
Comparison of the Effectiveness of Mat Pilates and Reformer Pilates in Women With Non-Specific Low Back Pain
In this study, the effects of instrumental pilates, mat pilates and general posture exercises on pain, disability, quality of life, flexibility and endurance of trunk extension muscles were researched in women with non-specific…
- Trial name
- NCT07134309
- Testing
- Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Musculoskeletal Pain, Low Back Pain
Biotensegrity: Thoracolumbar Fascial Integrity in Chronic Low Back Pain
This is a prospective study on chronic low back pain patients aimed at investigating how findings on a physical examination and musculoskeletal ultrasound may correlate with myofascial damage in the lower back.
- Conditions
- Musculoskeletal Pain, Low Back Pain, Myofascial Pain
- Trial name
- NCT03940313
- Testing
- Prolotherapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ProloAustin
Chronic Pain, Low Back Pain
High Level Pulsed Heat Versus Low Level Steady Heat in Subjects With Chronic Low Back Pain
This study is a double blinded randomized active placebo controlled trial in subjects with chronic low back pain. The trial compares pain relief by a device that delivered high level pulsed heat (45 °C) to pain relief delivered…
- Conditions
- Chronic Pain, Low Back Pain, Heat, Analgesia
- Trial name
- NCT04109703
- Testing
- High Level Pulsed Heat delivered by Generation 5 devices from Soovu Labs Inc., Low Level (37 degrees C) delivered by the control device Generation 5 devices from Soovu Labs Inc.
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soovu Labs Inc.
Catastrophizing Pain, Pain, Somatic
The Association Between Conditioned Pain Modulation and Pain Catastrophizing in Chronic Low Back Pain
This study evaluates the potential association between pain catastrophizing thoughts and the ability to dampen pain via endogenous descending inhibition.
- Conditions
- Catastrophizing Pain, Pain, Somatic, Chronic Low Back Pain
- Trial name
- NCT03644810
- Testing
- PPT measurement, Pain catastrophizing scale, Cold Pressor Test
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Low Back Pain
Efficacy Of Non-Invasive High Power Laser Acupuncture Stimulation In Chronic Non-Specific Low Back Pain
This study will be conducted to answer the following question: Does high power laser acupuncture has any effect on pain, back range of motion, function, quality of life, fatigue and level of satisfaction in chronic nonspecific…
- Trial name
- NCT05970419
- Testing
- high power laser acupuncture (HPLA), conventional treatment
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Back Pain
Changes in Thoracolumbar Fascia Stiffness and Pain Parameters in Young Patients With Chronic Low Back Pain
This study aims to investigate the biomechanical parameters of thoracolumbar fascia (TLF) and pain-related properties including pain intensity, pressure pain threshold (ppt) and pain sensitivity in young adults with non-specific…
- Conditions
- Pain, Back Pain, Fascia
- Trial name
- NCT06537219
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atılım University
Low Back Pain
Correlation of Thoracolumbar Fascia Mechanical Properties and Compensate Mechanisms of Asymmetric Skeletal Muscle
The objective of three-year research is to investigate the relationship between thoracolumbar fascia tissue characteristics, lumbopelvic asymmetry, core muscle contractility, proprioception and standing balance in different ages…
- Trial name
- NCT02459366
- Where
- Taiwan
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Low Back Pain, Hydrotherapy
Effects of Photobiomodulation and Deep Water Running Training in Subjects With Low Back Pain.
Physical exercises proves to be an option to revert a vicious cycle and aggravation of the painful that chronic low back pain can provide, which can improve the mobility and stabilization of the spine, muscle strength, motor…
- Conditions
- Low Back Pain, Hydrotherapy, Exertion; Excess
- Trial name
- NCT03465228
- Testing
- Training and LED group, Training group, LED group
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Low Back Pain
The Effect Water-exercise on Low Back Pain and Sick Leave, Among Healthy Pregnant Women
To investigate the possible effect of an unsupervised water-exercise program, on the intensity of low back pain and the number of days spent on sick leave, among healthy pregnant women Our hypothesis is, that 45 minutes of water…
- Trial name
- WAPW (NCT02354430)
- Testing
- Water-exercise
- Where
- Denmark
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet