Clinical trials: Back Pain Lower Back
Back Pain
Effects of Cervicothoracic Mobility Program on Low Back Pain
The study will be a randomized control trial to determine the effects of the cervicothoracic mobility program on pain, range of motion, and function in patients with chronic back pain.
- Trial name
- NCT05347251
- Testing
- Cervicothoracic mobility program, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Back Pain, Chronic Pain
Improving Outcomes and Lowering Costs by Integration of Primary Care Providers and Pain Medicine Physicians for Pain Pts
This study will demonstrate that functional improvement measures over a 6-month period for chronic low back patients under the care of Primary Care Provider (PCP), using a therapeutic plan formulated initially by the Pain…
- Conditions
- Back Pain, Chronic Pain, Pain, Intractable
- Trial name
- NCT02484937
- Testing
- Group 2 (PCP Treatment), Group 1 (PMS Treatment)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rush University Medical Center
Low Back Pain
A Phase 3 Study of Tanezumab for Chronic Low Back Pain
This study will investigate the efficacy and safety of tanezumab 5 mg and 10 mg administered by subcutaneous injection seven times at 8 week intervals (56 weeks).
- Trial name
- TANGO (NCT02528253)
- Testing
- Tanezumab 5 mg SC, Tanezumab 10 mg SC, Tramadol PR oral
- Where
- 262 sites in United States, Canada and 7 more
- Volunteers
- 1,832 people
- Sponsor
- Pfizer
Low Back Pain
Comparison of Biofeedback Tools to Train the Transversus Abdominis Activation in Healthy Subjects
Introduction: Non specific low back pain (NSLBP) is a low back pain (LBP) that cannot be attributable to a known pathology. LBP has prevalence as high as 84%, making it a heavy burden for health services and society worldwide.
- Trial name
- NCT03543501
- Testing
- Real-time ultrasound imaging feedback, PBU feedback
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Pain
Long-term Safety of PF-00345439 (Oxycodone)
Long-Term Safety Of PF-00345439 (Oxycodone) In Patients With Moderate To Severe Chronic Low Back Pain Or Osteoarthritis
- Trial name
- NCT01559701
- Testing
- PF-00345439
- Volunteers
- 823 people
- Sponsor
- Pain Therapeutics
Chronic Low-back Pain
Brain Imaging Biomarkers for Response to Spinal Cord Stimulation in Patients With Chronic Low Back Pain
In this protocol, "Brain imaging biomarkers for response to Spinal Cord Stimulation in patients with chronic low back pain," the investigators plan to perform brain mapping studies in 42 patients who are undergoing spinal cord…
- Trial name
- NCT04658628
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, Los Angeles
Degenerative Disc Disease
Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain
The primary purpose of this study is to evaluate the efficacy of rexlemestrocel-L+HA compared to control in reducing low back pain at 12 months post-treatment and safety of a single injection of rexlemestrocel-L+HA injected into…
- Trial name
- HyaluronicAcid (NCT06325566)
- Testing
- Rexlemestrocel-L + HA mixture, Saline
- Where
- 40 sites in United States
- Volunteers
- 300 people
- Sponsor
- Mesoblast, Ltd.
Non Specific Low Back Pain
Comparative Effect of Diaphragmatic Training in Patients With Chronic Non-specific Low Back Pain
Background: The diaphragm muscle is a respiratory muscle with postural function. Patients with chronic LBP (CLBP) are more susceptible to diaphragm fatigue than healthy people and, therefore, can likely benefit from exercises…
- Trial name
- NCT07167212
- Testing
- Diaphragm Training, Myofascial Release Technique
- Where
- Pakistan
- Sponsor
- Rashid Latif Medical College
Low Back Pain
Radiographic and Inflammatory Biomarker Changes in Chronic Low Back Pain
OBJECTIVE: To find and compare the effects of isokinetic training and virtual reality training on pain intensity, trunk muscle strength, radiographical (muscle cross-sectional area and muscle thickness), and biochemical effects…
- Trial name
- NCT05253599
- Testing
- Isokinetic training, Virtual reality training, Exercises
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Low Back Pain
Effects of Retro Walking in Chronic Non-specific Low Back Pain
Chronic low back pain (CLBP) is a clinical entity that can be defined as back pain with duration of more than 12 weeks. Chronic low back pain is associated with restriction in daily physical activities that ultimately leads to…
- Trial name
- NCT05044702
- Testing
- Retro walking, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Paraspinal Muscles, Low Back Pain
Multimodal Exercise Therapy for Non-Surgical Intervention of Nonspecific Low Back Pain.
This multicenter, assessor-blinded, two-arm parallel randomized controlled trial (N = 314) will compare the efficacy and safety of a 6-week multidimensional exercise program plus usual pharmacological care (experimental arm)…
- Conditions
- Paraspinal Muscles, Low Back Pain, Machine Learning, Radiomics
- Trial name
- METNLBP (NCT07353372)
- Testing
- Multidimensional exercise intervention, Oral NSAIDs
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Xuanwu Hospital, Beijing
Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb
Cost Effectiveness of OMT for Chronic Low Back Pain
The specific aim of this study is to conduct a prospective, multicenter cohort study over four months to compare the cost of standard of allopathic care (control group, N=90) versus standard of care plus osteopathic manipulative…
- Conditions
- Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb, Lesion of Sciatic Nerve, Right Lower Limb, Lumbar Spinal Stenosis
- Trial name
- NCT03532230
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Rowan University
Diaphragm; Relaxation, Low Back Pain
Influence of Manual Relaxation of the Diaphragm on the Tension of the Posterior Superficial Fascia
The diaphragm performs many functions that are vital to the body as a whole. Some of them are not related only to ventilation. The diaphragm is part of the myofascial system in the human body.
- Trial name
- NCT05197907
- Testing
- Fascial release of diaphragm muscle., Classic massage of the abdomen.
- Where
- Poland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Chronic Low Back Pain
Clinical Study to Evaluate the Safety and Efficacy of Heating and Cooling Combination Therapeutic Device(OCH-S100)
The purpose of this study is to verify the efficacy and safety of heating and cooling combination therapeutic device (OCH-S100) for patients with chronic low back pain (LBP).
- Trial name
- NCT02289170
- Testing
- Heating and cooling combination therapy
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Eun Jung Kim
Mild to Moderate Chronic Low Back Pain
The Efficacy of the no!no!Back for Chronic Low Back Pain
This pilot study is designed to evaluate the efficacy of the no!no!Back continuous passive motion device in relieving of mild to moderate non-specific low back pain.
- Trial name
- LBP-1 (NCT01620281)
- Testing
- no!no!Back
- Where
- Israel
- Volunteers
- 36 people
- Sponsor
- Radiancy
Low Back Pain, Recurrent
Treatment of Veterans With Chronic Low Back Pain
The purpose of this study is to assess the effectiveness of hypnosis in the treatment of chronic low back pain.
- Trial name
- CLBP (NCT00361270)
- Testing
- Hyp-8, Hyp-2 w recordings, Hyp-8 w recordings
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- VA Office of Research and Development
Intractable Neuropathic Pain, Pain
Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity
The primary objective of this study is to compare the efficacy and patient preference for spinal cord stimulation (SCS) using the Precision device with the electrode array placed at T7 versus placement at T8.
- Conditions
- Intractable Neuropathic Pain, Pain, Back Pain, Lower Extremity Pain
- Trial name
- NCT00399841
- Testing
- Precision for Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Boston Scientific Corporation
Low Back Pain
Photobiomodulation Therapy on Inflammatory Mediators on Low Back Pain
Low back pain (LBP) is ranked as one of the most prevalent health conditions. It is likely that some inflammatory mediators could be associated with pain and disability in these patients.
- Trial name
- NCT03859505
- Testing
- Active PBMT
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Universidade Cidade de Sao Paulo
Chronic Low-back Pain (cLBP), Chronic Low-back Pain
Effectiveness of a Multidisciplinary Treatment for Patients With Chronic Low Back Pain
PAINDOC is a treatment program that includes 4 disciplines that, separately, have demonstrated their effectiveness in the treatment of chronic low back pain: education in pain neuroscience, therapeutic education (Empowered…
- Conditions
- Chronic Low-back Pain (cLBP), Chronic Low-back Pain, Back Pain
- Trial name
- PAINDOC (NCT06679205)
- Testing
- Multidisciplinary and multimodal intervention, Usual Care
- Where
- 2 sites in Spain
- Volunteers
- 62 people
- Sponsor
- University of Barcelona
Multi-Organ Disorder
Pulsed RF Neuromodulation and Leukocyte-Rich PRP for Refractory Low Back Pain
This clinical trial aims to check the safety and efficacy profile of pulsed radiofrequency (RF) neuromodulation combined with leukocyte-rich platelet-rich plasma (PRP) injections for the treatment of refractory low back pain due…
- Trial name
- Multifidus (NCT06524531)
- Testing
- Pulsed RF Neuromodulation, Leukocyte-Rich PRP Injection, Physiotherapy Alone
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Iffat Anwar Medical Complex
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