Clinical trials: Back Pain Lower Back
Low Back Pain
Accuro Versus Traditional Landmark Palpation Technique to Determine Accurate Spinal Level for Procedures
Currently, at UVA, handheld ultrasound devices (like those used to view an unborn baby) are only two dimensional. The Accuro is a three dimensional handheld ultrasound device.
- Trial name
- NCT02862964
- Testing
- identify L4/L5
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Virginia
Chronic Low-back Pain
Pain Types and Pain Severity in Chronic Low Back Pain
The aim of this study is to characterize the distribution of pain phenotypes in people with chronic low back pain and to determine the effects of pain phenotypes on pain severity, functional status and quality of life.
- Trial name
- NCT05604027
- Testing
- Visual Analogue Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Low Back Pain, Recurrent
Exercise Therapy for Recurrent Low Back Pain: Unraveling the Puzzle of Peripheral Muscle and Central Brain Changes (B670201420984)
Exercise therapy has been shown to be effective in decreasing pain and improving function for patients with recurrent low back pain (LBP).
- Trial name
- ExTraS (NCT05706103)
- Testing
- Specific skilled motor training, General extension training
- Where
- Belgium
- Volunteers
- 62 people
- Sponsor
- University Ghent
Radiculopathy, Sciatica
Pain Treatment for Sciatica
This study will test the effectiveness of two drugs-nortriptyline and MS Contin (a type of morphine)-to treat pain caused by lumbar radiculopathy, or sciatica.
- Trial name
- NCT00009672
- Testing
- Nortriptyline, Morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Sciatica
Efficacy of Epidural Etanercept in the Treatment of Sciatica
Tumor necrosis factor (TNF)-alpha has been strongly implicated as a major contributing factor for the development of radiculopathy.
- Trial name
- NCT00364572
- Testing
- epidural injection of etanercept
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
Osteoarthritis, Low Back Pain
An Exploratory Study of Tramadol Hydrochloride in Patients With Osteoarthritis of the Knee or Low Back Pain
The purpose of this study is to find the clinical dose range of an active ingredient of JNS013 - Tramadol hydrochloride in chronic-pain patients who cannot attain a sufficient analgesic effect from non-steroidal anti-inflammatory…
- Trial name
- NCT00752661
- Testing
- Tramadol Hydrochloride; JNS013
- Volunteers
- 119 people
- Sponsor
- Janssen Pharmaceutical K.K.
Lower Back Pain
Investigating the Effects of a Spinal Mobilisation Intervention in People With Lower Back Pain
The objective of the study is to measure and analyse the effect of a spinal mobilisation intervention on muscle tissue quality in people with lower back pain.
- Trial name
- NCT04012970
- Testing
- Manual spinal mobilisations
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Edinburgh Napier University
Low Back Pain
Enhanced Implementation of Low Back Pain Guidelines in General Practice
The aim of this study is to evaluate whether an enhanced strategy of implementation of the new guideline will lower the number of patients getting referred to secondary care spine centres compared to a normal implementation…
- Trial name
- NCT01699256
- Testing
- Guideline implementation as usual, Enhanced guideline implementation strategy
- Where
- Denmark
- Volunteers
- 1,101 people
- Sponsor
- University of Aarhus
Dysmenorrhea, Low Back Pain
Core Stability vs. Traditional Physical Therapy: A Comparative Study on Alleviating Low Back Pain in Dysmenorrhea
Dysmenorrhea is a menstrual disorder defined by the presence of painful cramps of uterine origin that occur during menstruation.
- Trial name
- NCT06807229
- Testing
- Transcutaneous electrical nerve stimulation, stretching exercises
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Delta University for Science and Technology
Low Back Pain
PRoGReSS-PS: Patient Response to GRraded Sensory Stimulation: A Pilot Study
The Patient Response to Graded Sensory Stimulation-Pilot Study (PRoGReSS-PS) will measure back pain perceptions in participants who receive either chiropractic treatment or foot massage.
- Trial name
- PRoGReSS-PS (NCT01842737)
- Testing
- Spinal treatment, Massage
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Palmer College of Chiropractic
Myofascial Pain Syndrome
Massage of the Low Back Muscles Assessed With Ultrasound Scanning
The aim of the study is to use diagnostic ultrasound to compare the thickness of soft tissues in the low back in a group of patients with chronic low back pain treated with massage to a control group of non-treated patients.
- Trial name
- NCT01174667
- Testing
- Specific massage for fascial release, Quiet non-instructed rest for 3 minutes
- Volunteers
- 70 people
- Sponsor
- Anglo-European College of Chiropractic
Chronic Sacroiliac Joint Pain
Cryoneurolysis vs Radiofrequency Ablation for Chronic Sacroiliac Joint Pain
This is a single-center, randomized, open-label, pilot study in adult subjects with chronic sacroiliac joint (SIJ) pain. Thirty (30) subjects are planned for initial enrollment and will be randomized 1:1 to receive ioveraº…
- Trial name
- NCT06935539
- Testing
- Cryoneurolysis, Radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- Medical Pain Management Services, PLLC
Pain, Chronic, Musculoskeletal Pain
Complementary Management of Chronic Neck and/or Low Back Pain With a Pain Relief Kit
The purpose of this project is to determine the effect of a multimodal non-pharmacological Pain Relief Kit on the pain, functioning, patient satisfaction, and opioid consumption of individuals suffering from an acute pain episode…
- Conditions
- Pain, Chronic, Musculoskeletal Pain, Low Back Pain, Neck Pain
- Trial name
- NCT03157544
- Testing
- multimodal non-pharmacological Pain Relief Kit
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Low Back Pain, Sciatica
Magnets in the Treatment of Sciatica
Despite much popularity among the public, magnetic devices used for the treatment of various musculoskeletal and neuropathic pain syndromes have been the subject of few randomized controlled trials.
- Trial name
- NCT00044109
- Testing
- Magnets
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Chronic Low-back Pain, Muscle Atrophy
Effect of an Aquatic Exercise Program in Patients With Chronic Low Back Pain
The goal of this pilot randomized controlled trial is to compare the effects of aquatic therapy versus standard care on paraspinal and gluteal morphology and function in individuals with chronic low back pain.The main questions…
- Conditions
- Chronic Low-back Pain, Muscle Atrophy, Diagnostic Imaging, Exercise Therapy
- Trial name
- NCT05823857
- Testing
- Aquatic Therapy, Standard Care
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Concordia University, Montreal
Back Pain, Leeches
Complementary Medicine Practices in Chronic Low Back Pain: Randomized Controlled Trial
To compare the effectiveness of classical physiotherapy and leech therapy in patients with chronic low back pain.
- Conditions
- Back Pain, Leeches, Chronic Pain
- Trial name
- NCT06407492
- Testing
- Leech, Conventional Physiotherapy, Kinesiotape
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Low Back Pain, Veterans Family
Improving Veteran Access to Integrated Management of Back Pain
The purpose and objective of this pragmatic trial is to examine the effectiveness of two different quality improvement care pathways for low back pain (LBP); a sequenced, integrated care pathway (ICP) and 2) a coordinated, care…
- Trial name
- AIM-BACK (NCT04411420)
- Testing
- Pain modulation with physical pain treatment, Telephone delivered self-management counseling for increasing physical activity, Telephone delivered behavioral treatment for participants with high risk for continued disability
- Where
- United States
- Volunteers
- 1,817 people
- Sponsor
- Duke University
Central Sensitization, Manual Therapy
Efficiency of Manual Therapy on Central Sensitization in Patients With Nonspecific Chronic Back Pain
Central sensitization (CS) is defined as the increased responsiveness of nociceptive neurons in the central nervous system to normal or subthreshold afferent input.
- Trial name
- NCT05937503
- Testing
- manual therapy, conventional physiotherapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atılım University
Low Back Pain
The Effect of Dry Needling on Trunk Muscle Function in Low Back Pain Patients
The study will establish data on the function of trunk muscles in healthy and low back pain patient's pre and post dry needling treatment.
- Trial name
- NCT02250742
- Testing
- dry needling
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Radiculopathy, Herniated Disk
Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Approximately 300,000 patients undergo open surgical procedures to treat symptoms caused by disc herniation. Among the various surgical techniques practiced the percutaneous discectomy occupies its space since the first…
- Trial name
- PDOP_TLR (NCT01367860)
- Testing
- Open microdiscectomy, Percutaneous Diskectomy SpineJet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
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