Clinical trials: Bacteria
Ulcerative Colitis, Intestinal Bacteria Flora Disturbance
Fecal Microbiota Transplantation for Ulcerative Colitis
Ulcerative colitis is a common digestive system disease, the incidence is increasing in recent years.It is reported that the occurrence and development of ulcerative colitis is closely related to imbalance of intestinal flora…
- Conditions
- Ulcerative Colitis, Intestinal Bacteria Flora Disturbance, Fecal Microbiota Transplantation
- Trial name
- FMTFUC (NCT03016780)
- Testing
- Fecal Microbiota Transplantation, Normal Saline
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chengdu Medical College
Skin Bacteria
Comparing Skin Disinfectants Before Labour Epidural Analgesia
The purpose of this study is to compare the current standard skin disinfectant solution for labour epidurals used at BC Women's Hospital to another common skin disinfectant and to the skin disinfectant solution recommended by the…
- Trial name
- NCT00247897
- Testing
- Skin antisepsis
- Where
- Canada
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ventilator Associated Pneumonia
Efficacy Study of Colistimethate Sodium Inhalation in Patients With Ventilator-associated Pneumonia
There might be additional benefit on clinical outcomes from adjunctive colistimethate sodium inhalation as therapy for multidrug resistant Gram-negative ventilator-associated pneumonia.
- Trial name
- NCT01975350
- Where
- Taiwan
- Volunteers
- 49 people
- Sponsor
- National Taiwan University Hospital
Eczema
Omega-3 Monoglyceride Based Topic Products as Skin Prebiotics for Eczema
This exploratory study aims to verify the impact on the severity of eczema as well as the prebiotic potential of a daily application of Omega-3 serum and cream on a skin with eczema.
- Trial name
- NCT06155513
- Testing
- Omega-3 monoglyceride based topical Serum and cream of formulation A (light), Omega-3 monoglyceride based topical Serum and cream of formulation B (rich)
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- SCF Pharma
Primary Hypertension
Dietary Nitrate and the Oral Microbiome in Children With Primary Hypertension
Children and adolescents with primary hypertension (high blood pressure without an underlying secondary cause) are at increased risk of cardiovascular disease in adulthood.
- Trial name
- NCT07236125
- Testing
- No active intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yelda Kasımoğlu
Community-acquired Pneumonia
Role of Multiplex PCR in CAP
1. role of multiplex PCR in early identifying bacteria in patients with lower respiratory tract infection. 2. effect of early starting targeted antibiotics on outcome
- Trial name
- NCT06097117
- Testing
- MultiplexPCR
- Volunteers
- 66 people
- Sponsor
- Assiut University
Total Knee Replacement Surgery
Iodine Impregnated Incision Drapes and Bacterial Recolonization in Simulated Knee Surgery. A Controlled Randomized Experimental Trial.
This study evaluates the effect of Iodine-impregnated self-adhesive plastic drapes (IIAD) on the quantity of skin bacteria, which is a known factor in the development of surgical site infections in orthopedic surgery.
- Trial name
- NCT02342561
- Testing
- Ioban 2 incision drape, 3M
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Gram-negative Bacteraemia
Early Oral Switch for Uncomplicated Gram-negative Bacteraemia
Current management of uncomplicated Gram-negative bacteraemia entails prolong intravenous (IV) antibiotic therapy with limited evidence to guide oral conversion.
- Trial name
- INVEST (NCT05199324)
- Testing
- Oral fluoroquinolones (most commonly, ciprofloxacin) or oral trimethoprim-sulfamethoxazole, Standard of care intravenous antibiotics (e.g. ceftriaxone, cefazolin)
- Where
- 25 sites in Australia, Greece and 9 more
- Volunteers
- 720 people
- Sponsor
- Tan Tock Seng Hospital
Allergic Asthma, Allergic Rhinitis
Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis, Asthma and Allergic Rhinitis
The prevalence of allergic diseases (atopic dermatitis, asthma, rhinitis, conjunctivitis and food allergy) has increased dramatically in industrialized countries over the last 20-30 years.
- Conditions
- Allergic Asthma, Allergic Rhinitis, Atopic Dermatitis
- Trial name
- Prévall-DP (NCT02908360)
- Testing
- double positive T cells (CD4 + / CD8 +) to the specific peripheral blood of F prauznitzii analyse
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Nantes University Hospital
Pneumonia, Bacterial
Urease Breath Test for Rapid Characterization of Pneumonia
This is a Phase 1, open label, evaluation of a 13C-urea breath test for the detection of urease-producing bacteria in patient with pneumonia in the emergency department.
- Trial name
- NCT03100760
- Testing
- 13C-urea breath test
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of New Mexico
Lung Infection Bacterial
Polycolistin E Sodium Mesylate Combined With Intravenous Atomization for Carbapenem Resistant Gram-negative Bacteria in Pulmonary Infection
Pulmonary infection is a kind of infectious disease that seriously damages human health. It usually starts quickly and progresses rapidly in clinical manifestations, and is often accompanied by upper respiratory tract infection…
- Trial name
- NCT06907069
- Testing
- Intravenously atomized polycolistin E sodium mesylate
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Fecal Analysis
Fecal Recovery of the Probiotic Bacteria Lactobacillus Rhamnosus GG (LGG) and Bifidobacterium Animalis Subspecies Lactis BB-12 (BB-12) in Healthy Humans Following Daily Consumption of a Probiotic Supplement
The main hypothesis of this study is that there will be a significant increase of Lactobacillus rhamnosus GG (LGG) and Bifidobacterium lactis (BB-12) in the stool of healthy humans following daily consumption of a probiotic…
- Trial name
- LGG BB-12 (NCT01757054)
- Testing
- ProNutrients Probiotic
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Pfizer
Oral Surgical Procedures
The Comparison of Microbial Adherence to Various Sutures in Patients Undergoing Oral Surgery
The final stage of any surgical procedure is suturing. Sutures have a vital rule in wound healing- they are responsible for flaps approximation, hemostasis and restoring function and esthetics.
- Trial name
- NCT02653924
- Testing
- silk suture, vicryl suture, nylon suture
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Black Stains
Black Stains' Epidemiology, Clinical Evaluation and Dietary Habits: a Clinical Trial.
The aim of this study is to investigate epidemiology and treatment possibilities of black stains, with the assessment of a possible correlation with patients' dietary habits. Patients will be randomly divided into three groups.
- Trial name
- NCT04865796
- Testing
- Lactoferrin products, Probiotics products, Standard home oral care
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- University of Pavia
Periodontitis
P. Gingivalis IgG Titer Test for Periodontitis
This study was performed to evaluate prospectively the diagnostic utility of a blood IgG antibody titer test against periodontal pathogens.
- Trial name
- NCT01658475
- Where
- 12 sites in Japan
- Volunteers
- 1,387 people, healthy volunteers welcome
- Sponsor
- Okayama University
Irritable Bowel Syndrome
The Impact of Dietary Treatment in Patients With Irritable Bowel Syndrome
The obtained results are likely to determine whether changes in the diet of patients with irritable bowel syndrome will affect their nutritional status.
- Trial name
- NCT04307368
- Testing
- FODMAP diet, Elimination-rotational diet, Classic diet
- Volunteers
- 73 people
- Sponsor
- Medical University of Bialystok
Prostatitis, Chronic Prostatitis
Microbiome of Urologic Chronic Pelvic Pain Syndrome
This research is being done to learn more about the bacteria that live in the genito-urinary tract in subjects with urologic chronic pelvic pain syndrome (UCPPS).
- Conditions
- Prostatitis, Chronic Prostatitis, Interstitial Cystitis, Painful Bladder Syndrome
- Trial name
- NCT03027076
- Testing
- Genitourinary Specimen Collection, Collect midstream urine samples
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Bacterial Growth, Novel Influenza A (H1N1)
The Research of Novel Electrolyzed Water Spray to Eradicate Bacteria E-coli and an Attenuated Human Flu Virus
The purpose of this study is to test whether spraying the hand of patients by use of the novel electrolyzed water spray will decrease the number of bacteria E-coli and the virus titer of an attenuated human flu virus.
- Trial name
- NCT05797103
- Testing
- A novel electrolyzed water spray reduces numbers of bacteria E-coli and an attenuated human flu virus on human hands
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dove Medical Press Ltd
Early Childhood Caries
Effectiveness Fluoride Varnishes in Children With Early Childhood Caries
The study was carried out in 88 children with severe early childhood caries (dmfs≥age +1) who were referred to the investigators' clinic.
- Trial name
- NCT03625310
- Testing
- Sodium Fluoride, Sodium Fluoride with TCP, Sodium Fluoride with CXP
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Merve Erkmen Almaz
Viral Infection, Sepsis
COMPArative Study of the Consequence on innaTe Immune Response du to Bacterial or Viral Infection in Patients Admitted to Intensive Care Unit
Patient admitted in intensive care unit (ICU) for acute infection whether it be viral or bacterial had major impairment of the immune response.
- Trial name
- COMPACT (NCT05671159)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Limoges