Clinical trials: Bacteria
Bacteria Microflora Reduction
Pilot Evaluation of Two Test Materials With a Positive Control When Used as a Patient Preoperative Skin Preparation
Comparative Study of Antimicrobial Effectiveness Evaluation of 26ml Project X, 5.1ml Project X and Prevantics Maxi Swabstick following ASTM E1173 - Standard Test Method for Evaluation of Preoperative, Precatheterization, or…
- Trial name
- NCT03861780
- Testing
- Project X 26ml, Project X 5.1ml, Prevantics Maxi Swabstick
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Professional Disposables International, Inc.
Microbial Colonization
Microbial Colonization of Oral Probiotics
The aim of this study is to evaluate the colonization efficacy of probiotic lozenges and powders containing specific prebiotics in healthy adults
- Trial name
- NCT05375383
- Testing
- Streptococcus salivarius K12 lozenge, Probiotic S. salivarius K12 lozenges containing prebiotic A, Probiotic S. salivarius K12 lozenges containing prebiotic B
- Where
- New Zealand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BLIS Technologies Limited
Surgical Site Infection
INtestinal Dysbiosis and TRanslocation of Bacteria in Patients Undergoing Surgery
The goal of this observational study is to contribute to a better understanding of the perioperative kinetics of intestinal microbial composition and association with surgical site infections.
- Trial name
- INTRA (NCT05775341)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lactose Malabsorption
Acid Lactase in Combination With Yoghurt Bacteria for Improvement of Lactose Digestion in Lactose Malabsorbers
Fermented dairy products, especially real Yoghurt, are often tolerated better by lactose malabsorbers than unfermented dairy products.
- Trial name
- NCT01593631
- Testing
- Acid lactase, Lyoph. yoghurt bacteria, Acid lactase plus yoghurt bacteria
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vitacare Gmbh & Co. KG
Intestinal Bacteria Growth
The Impact of Dietary Flavanols on the Gut Microflora
The primary propose of this study is to determine the impact of flavanol-rich cocoa on the growth of the human gut microbiota.
- Trial name
- NCT01091922
- Testing
- Low flavanol cocoa beverage, High flavanol cocoa beverage
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Reading
General Population
Capture of Healthy Gut Bacteria Associated to High Fiber Diet
The role of the intestinal microbiota on health is now well recognised, and diet is one of the factors influencing the maintenance of a healthy intestinal microbiota.
- Trial name
- iTARGET (NCT06166810)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Bacteria, Microbiota
Standardized Fecal Microbiota Transplantation for Ulcerative Colitis
The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body's metabolism.
- Conditions
- Bacteria, Microbiota, Fecal Microbiota Transplantation, Inflammatory Bowel Disease
- Trial name
- NCT01790061
- Testing
- Standardized FMT, Traditional treatments
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The Second Hospital of Nanjing Medical University
IBS-D (Diarrhea-predominant), IBS (Irritable Bowel Syndrome)
Lactic Acid Bacteria in Functional Diarrheal Disorders
The goal of this clinical trial is to learn whether a probiotic supplement can improve symptoms and quality of life in adults with diarrhea-predominant irritable bowel syndrome (IBS-D) or functional diarrhea (FD).
- Conditions
- IBS-D (Diarrhea-predominant), IBS (Irritable Bowel Syndrome), Functional Diarrhea
- Trial name
- NCT07916688
- Testing
- LL1500
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Szeged University
Antibiotic Resistant Infection
Antibiotic Resistance in Global Pediatric Oncology Centers
Antibiotic resistance is one of the major health threats facing global as well as domestic populations, however it is not well characterized in pediatric patients.
- Trial name
- NCT03721562
- Where
- 5 sites in United States, El Salvador and 2 more
- Volunteers
- 560 people
- Sponsor
- St. Jude Children's Research Hospital
Multi-drug Resistant Bacteria
Standard Precautions Versus Contact Additional Precautions Against Multi-drug Resistant Bacteria in Intensive Care Unit (PSBMR)
The national recommendations promote the applying of the Contact Additional Precautions (CAP) with the Standard Precautions (SP) to limit the transmission of multi-drug resistant (MDR) bacteria.
- Trial name
- PSBMR (NCT02890433)
- Where
- France
- Volunteers
- 3,124 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Influenza
Evaluation of the Safety and Effectiveness of a Probiotic Bacterium to Boost the Immune Response to Influenza Vaccines
This project aims to test the hypothesis that oral consumption of a specific strain of the probiotic bacterium Lactobacillus fermentum (trademarked PCC®) is able to significantly enhance the immune response to a vaccine for…
- Trial name
- NCT00294788
- Testing
- Fluvax, PCC® (Lactobacillus fermentum VRI 003)
- Where
- Australia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Probiomics Ltd
Human Gut Microbiome Development
Phages Dynamics and Influences During Human Gut Microbiome Establishment
Microbial communities are key components of human environment. Consequently, human gut microbiome have been extensively studied providing a better understanding of the relations between bacterial populations and host physiology.
- Trial name
- METAKIDS (NCT03296631)
- Testing
- collection of diapers with fresh stools
- Where
- 2 sites in France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Cardiovascular Disease
Sex Differences in Oral Bacteria
Females have a lower incidence of hypertensive and cardiovascular disorders that may relate to differences in nitrogen oxides in the blood and saliva.
- Trial name
- NCT01583803
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Premature Ovarian Failure (POF)
The Influence of Gut Microbiota on Ovarian Function: A Single-center, Randomized,Double Blind, Parallel-controlled, Exploratory Clinical Trial
In order to study the community profile of the intestinal microbiome in women with ovarian dysfunction, as well as the relationship between the changes in the intestinal microbiota and sex hormones, this study recruited 30 women…
- Trial name
- NCT07308327
- Testing
- Akk Gut Bacteria Supplement
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Songling Zhang
Wounds
Positive Predictive Value of the MolecuLight i:X Imaging Device to Predict the Presence of Bacteria in Chronic Wounds
This is a non-randomized evaluation for which 50 patients will be imaged at the Southwest Regional Wound Care Center, Lubbock, Texas, who present with a chronic wound and are receiving standard treatment.
- Trial name
- NCT02682069
- Testing
- MolecuLight i:X Imaging Device
- Volunteers
- 30 people
- Sponsor
- MolecuLight Inc.
Diarrhea
Etiology of Diarrhea in Guinea-Bissau and in Finland
Diarrhoea is the leading cause of death in the world with 2.2 million deaths every year. The majority of deaths are among children in developing countries, but the travellers encounter the disease as well.
- Trial name
- NCT01269554
- Where
- 3 sites in Finland, Guinea-Bissau
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Attention Deficit Hyperactivity Disorders, Caries, Dental
Salivary Bacteria and Oral Health Status in Children With ADHD
Attention deficit and hyperactivity (ADHD) affect 6% of school-aged children. Few studies reported higher prevalence of caries and restorations among children with ADHD. Methylphenidate is the drug of choice to treat ADHD.
- Conditions
- Attention Deficit Hyperactivity Disorders, Caries, Dental, Xerostomia
- Trial name
- ADHD (NCT00966394)
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Hospital Infection
Efficacy of Polymyxin B Against Infections Caused by Extensively Drug-resistant (XDR) Gram-Negative Bacteria
The objective of the study is to evaluate the efficacy of Polymyxin B for treatment Gram negative bacterial infection. The hypothesis of study is Polymyxin B would be the new antibacterial agents for Thai Gram negative infected…
- Trial name
- XDR (NCT02328183)
- Testing
- Polymyxin B
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Skin Diseases, Infection
Study Evaluating Tigecycline Versus Clindamycin Or Vancomycin On Complicated Skin And Skin Structure Infections Including Those Due To Methicillin-Resistant Staphylococcus Aureus (MRSA) In Pediatric Subjects
The main purpose of this study is to compare the safety and efficacy of tigecycline versus clindamycin (including subjects treated with vancomycin) in pediatric subjects (aged 8 to 17 years) with complicated skin and skin…
- Trial name
- NCT00911573
- Testing
- Tigecycline, Clindamycin (or Vancomycin if needed)
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Diabetic Foot Ulcer
Efficacy of LL-37 Cream on Bacteria Colonization, Inflammation Response and Healing Rate of Diabetic Foot Ulcers
Diabetic foot ulcer (DFU) is a common complication of diabetes with global prevalence of 6.3%. Treatment of diabetic foot ulcer (DFU) is challenging with disappointing outcome.
- Trial name
- NCT04098562
- Testing
- LL37, Standard Wound Care
- Where
- 3 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Fakultas Kedokteran Universitas Indonesia