Clinical trials: Bacterial Overgrowth
Small Intestine Problem
Metabolomics in Small Intestinal Bacterial Overgrowth
Small intestinal bacterial overgrowth (SIBO) is a condition where a person's own good and useful germs, live in parts of the bowel where there should not be any germs.
- Trial name
- MESIBO (NCT04057560)
- Volunteers
- 50 people
- Sponsor
- United Lincolnshire Hospitals NHS Trust
Small Intestinal Bacterial Overgrowth
Hydrogen and Methane Breath Test Questionnaire
Lactulose HMBT and Glucose HMBT are simple non-invasive tests to assess whether imbalances in gut bacteria may be contributing to troublesome tummy symptoms.
- Trial name
- HMBTQ (NCT05122520)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 1,040 people
- Sponsor
- The Functional Gut Clinic
Upper Respiratory Tract Infections
Controlled Trial to Evaluate a Local Information Campaign on Antibiotic Prescribing in Italy
Use of information campaigns and educational interventions directed to citizens and supported by physicians, aimed at promoting the appropriate use of medicines, have been evaluated by several studies with conflicting results.
- Trial name
- LOCAAL (NCT01604096)
- Testing
- Multifaceted information campaign
- Where
- 2 sites in Italy
- Sponsor
- Regional Health and Social Care Agency, Italy
Small Intestine Bacterial Overgrowth
Nutrition, Overgrowth, and Vaccine Efficacy in Low-income Settings
The purpose of this study is to assess the impact of small intestine bacterial overgrowth (SIBO) on childhood nutritional status, growth, and oral vaccine efficacy.
- Trial name
- NOVEL (NCT02745327)
- Where
- Bangladesh
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Chronic Rhinosinusitis, Rhinosinusitis
Xylitol for Chronic Sinusitis
The purpose of this investigation is to conduct a randomized controlled trial within a subgroup of difficult-to-treat patients with CRS, evaluating the use of topical xylitol treatment concurrently with topical…
- Conditions
- Chronic Rhinosinusitis, Rhinosinusitis, Sinusitis, Drain Sinus
- Trial name
- NCT03229551
- Testing
- Xylitol, Saline
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Constipation
Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut Transit
Patients with constipation often have bloating and abdominal distension. It is unclear if this is related to intestinal bacteria.
- Trial name
- NCT00844831
- Testing
- Lubiprostone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Louisville
Small Intestinal Bacterial Overgrowth, Critical Illness
Small Intestinal Bacterial Overgrowth in Critically Ill Patients
Small intestinal bacterial overgrowth (SIBO) syndrome, though associated with potentially serious complications, has not been adequately studied to date in critically ill patients hospitalized in intensive care units (ICU).
- Conditions
- Small Intestinal Bacterial Overgrowth, Critical Illness, Intensive Care Unit
- Trial name
- NCT05765994
- Testing
- Modified hydrogen breath test
- Where
- Greece
- Volunteers
- 52 people
- Sponsor
- University of Ioannina
Colon Cancer
Chronic Loose Stools Following Right-sided Hemicolectomy for Colon Cancer and the Association With Bile Acid Malabsorption and Small Intestinal Bacterial Overgrowth Using a Novel Sampling Device
The goal of this clinical research study is to learn about gastrointestinal symptoms in participants who have undergone SC or RC and their impact on the quality of life of these participants.
- Trial name
- NCT06927011
- Testing
- Capscan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Parkinson's Disease
Weight Loss in Parkinson's Disease and Role of Small Bowel Bacterial Overgrowth
The potential role of small bowel bacterial overgrowth (SBBO) in weight loss occurring in patients with Parkinson's Disease (PD) has not previously been examined.
- Trial name
- NCT01662791
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Mayo Clinic
Irritable Bowel Syndrome (IBS), Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Herbal Supplement (Biocidin REMOVE) for Bacterial Overgrowth in Irritable Bowel Syndrome
The goal of this clinical trial is to learn if an herbal supplement called Biocidin REMOVE can clear small intestinal bacterial overgrowth (SIBO) in adults with irritable bowel syndrome (IBS).
- Trial name
- NCT07768267
- Testing
- Biocidin REMOVE
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Functional Dyspepsia, Small Intestinal Bacterial Overgrowth
Small Intestinal Bacterial Overgrowth: A Prospective Registry
The purpose of this study is to investigate the prevalence of small intestinal bacterial overgrowth (SIBO) in patients who will be undergoing an enteroscopy as an outpatient procedure with symptoms of functional dyspepsia.
- Trial name
- SIBO (NCT01822470)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Small Intestinal Bacterial Overgrowth, SIBO
The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Related Gastrointestinal Symptoms
The goal of this study is to test the effect of a probiotic formulation on gastrointestinal symptoms, gut and small intestine microbiota in participants suffering from small intestinal bacterial overgrowth (SIBO).
- Trial name
- NCT06317441
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Nimble Science Ltd.
Resistance Bacterial, Increased Drug Resistance
Decreasing Irrational Antimicrobial Use in Bangladesh: A Digital Intervention Program
We developed 'SmartAMR', a digital pharmacy system featuring real-time records, symptom checks, telemedicine, counselling, and medication reminders.
- Conditions
- Resistance Bacterial, Increased Drug Resistance, Drug Resistance, Microbial
- Trial name
- SmartAMR (NCT06313619)
- Testing
- SmartAMR
- Where
- Bangladesh
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Urinary Tract Infections, Bacterial Resistance
Study to Assess Management and Outcomes of Hospitalised Patients With Complicated UTI (RESCUING)
A retrospective observational study to assess the clinical management and outcomes of hospitalised patients with complicated urinary tract infection in countries with high prevalence of multidrug resistant gram-negative bacteria…
- Trial name
- RESCUING (NCT02641015)
- Where
- 21 sites in Bulgaria, Greece and 6 more
- Volunteers
- 1,028 people
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge
Celiac Disease
Rifaximin for the Treatment of Persistent Symptoms in Patients With Celiac Disease
Celiac disease is a condition in which the small intestine is damaged by gluten, the storage protein of wheat and similar proteins in barley and rye.
- Trial name
- NCT01137955
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Bacterial Infections
Study Evaluating the Association of Antibiotic Measures and Control of Bacterial Resistance
Assess efficacy of piperacillin/tazobactam in reducing the cases of colonization and infection of bacteria.
- Trial name
- NCT01788449
- Volunteers
- 335 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Bacterial Resistance
Community Epidemiology and Typology of Third-generation Cephalosporins Resistant Enterobacteriaceae in Reunion Island
In its report dated april 2014, World Health Organization confirms antibiotic resistance dissemination in all parts of the world, in hospitals and in community and worries about a possible comeback to a pre-antibiotic era during…
- Trial name
- AB-RUN (NCT03226314)
- Testing
- stool sample
- Where
- Reunion
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
SIBO, Small Intestinal Bacterial Overgrowth
The Low FODMAP Diet in Individuals With Small Intestinal Bacterial Overgrowth (SIBO)
This study aims to assess the impact of a low FODMAP diet (LFD) on gastrointestinal symptoms and nutritional status in individuals diagnosed with small intestinal bacterial overgrowth (SIBO).
- Conditions
- SIBO, Small Intestinal Bacterial Overgrowth, Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
- Trial name
- NCT07424313
- Testing
- Low FODMAP Diet, Healthy Eating Diet
- Where
- Poland
- Volunteers
- 51 people
- Sponsor
- Warsaw University of Life Sciences
Irritable Bowel Syndrome
Lactulose and Glucose Breath Tests as Predictors of Clinical Benefit From Rifaximin in Irritable Bowel Syndrome
The Irritable Bowel Syndrome (IBS) is a frequent disease, affecting between 10 and 20% of general population. Several pathophysiologic mechanisms have been described in IBS, among them the role of intestinal microbiota and small…
- Trial name
- NCT01803724
- Where
- Chile
- Volunteers
- 120 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Chronic Idiopathic Constipation
Lubiprostone Effect on Gastrointestinal Tract Transit Times Measured by Smartpill in Patients With Chronic Constipation
The purpose of this study is to determine if lubiprostone may change the rate of movement of food and activities in the stomach and intestines in subjects whose gastrointestinal (GI) tract is slower due to constipation.
- Trial name
- NCT01469819
- Testing
- Lubiprostone
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso