Clinical trials: Bacterial Overgrowth Syndrome
Plaque Psoriasis
A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.
Background: Psoriasis is one of the hot spots in the field of skin disease prevention and treatment, and TCM topical preparations have unique advantages in the treatment of psoriasis.
- Trial name
- NCT06396013
- Testing
- Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment
- Volunteers
- 96 people
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Irritable Bowel Syndrome
Efficacy of Rifaximin to Treat Diarrhea-predominant Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a common disease and the pathogenesis of this disease includes central and peripheral mechanisms.
- Trial name
- NCT02565654
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Shoulder Tendinopathy, Shoulder Tendinitis
Electroacupuncture and Cupping for Shoulder Tendinitis
This study aims to evaluate the effectiveness of electroacupuncture combined with vacuum cupping therapy in treating simple periarthritis of the shoulder associated with the traditional medicine syndrome of Qi stagnation and…
- Trial name
- NCT07545785
- Testing
- Electroacupuncture, Vacuum Cupping Therapy
- Where
- 2 sites in Vietnam
- Volunteers
- 54 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Coronary Heart Disease, Stable Angina Pectoris
Studies of Traditional Chinese Medicine Clinical Efficacy Evaluation Index
The purpose of the trial is to take stable angina pectoris of coronary heart disease (CHD) as examples to build a standard evaluation system for efficacy of traditional Chinese medicine (TCM). 1.
- Trial name
- NCT01502943
- Testing
- Louxiangdan Tongxin granules, Chixiangshen Tongxin granules, Western basis treatment
- Where
- 10 sites in China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Liaoning University of Traditional Chinese Medicine
Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Small Intestinal Bacterial Overgrowth
A Trial of a Multi-Component Nutritional Supplement in Hydrogen-Dominant Small Intestinal Bacterial Overgrowth
The goal of this trial is to evaluate the safety and tolerability of an 8-week, multi-component nutritional supplement (AV1PD1A) in adults with hydrogen-dominant small intestinal bacterial overgrowth (SIBO).
- Trial name
- AV1-SIBO (NCT07215676)
- Testing
- AV1PD1A
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National University of Natural Medicine
Celiac Disease
Rifaximin for the Treatment of Persistent Symptoms in Patients With Celiac Disease
Celiac disease is a condition in which the small intestine is damaged by gluten, the storage protein of wheat and similar proteins in barley and rye.
- Trial name
- NCT01137955
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Cancer
The FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms"
The aim of the study is to identify how often gastrointestinal problems interfere with quality of life as a result of treatment for cancer with chemotherapy.
- Trial name
- FOCCUS (NCT02121626)
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Food Intolerance Syndromes, Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Combined Lactulose H2-breath Test With Abdominal Imaging
Hydrogen (H₂) breath tests serve several purposes. (i) detect malabsorption of carbohydrates such as lactose and fructose, (ii) measurement of oro-caecal transit time (iii) associate hydrogen production with the onset of…
- Conditions
- Food Intolerance Syndromes, Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Breath Tests
- Trial name
- NCT07145580
- Where
- Switzerland
- Volunteers
- 510 people
- Sponsor
- Klinik Arlesheim
Irritable Bowel Syndrome, Bacterial Overgrowth Syndrome
Atrantil for Intestinal Bacterial Overgrowth
Intestinal Bacterial Overgrowth (IBO) is a common functional condition due to excessive amounts of bacteria in the gastrointestinal tract.
- Conditions
- Irritable Bowel Syndrome, Bacterial Overgrowth Syndrome, SIBO
- Trial name
- NCT04755673
- Testing
- Atrantil (Medical Food)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Coronary Heart Disease (CHD)
Clinical Evidence Based and TCM Phenotype Group Study of Zhilong Huoxue Tongyu Capsule in the Treatment of Stable Angina Pectoris of Coronary Heart Disease (Qi Deficiency and Blood Stasis Syndrome)
This study intends to prove the clinical effect of Zhidong Huoxue Tongyu capsule in the treatment of stable angina pectoris with qi deficiency and blood stasis syndrome from the perspective of TCM syndrome differentiation and…
- Trial name
- NCT06709638
- Testing
- Zhilong Huoxue Tongyu capsule
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Jiang Hanmei
Coronary Heart Disease, Medicine, Chinese Traditional
HuoXin Pills Intervention on Patients With Coronary Heart Disease After Drug-Coated Balloon Implantation
This trial is a multi-center, randomized, double-blind, placebo, parallel controlled study. Objectively evaluates the curative effect of Huoxin Pills (concentrated pills) intervention on improving the prognosis of patients with…
- Trial name
- HAPPY-DCB (NCT05489016)
- Testing
- Yuekang Huoxin Pills (concentrated pills), Yuekang Huoxin Pills (concentrated pills)simulant
- Where
- 3 sites in China
- Volunteers
- 440 people
- Sponsor
- China National Center for Cardiovascular Diseases
Staphylococcus Haemolyticus, Staphylococcal Infections
Staphylococcus Haemolyticus in the Neonatal Intensive Care Unit of CHSD in 2023: Analysis and Trends
This study looks at cases of Staphylococcus haemolyticus infections in newborns hospitalized in the Neonatal Intensive Care Unit (NICU) at the Saint-Denis Hospital in 2023.
- Conditions
- Staphylococcus Haemolyticus, Staphylococcal Infections, Sepsis, Catheter-Related Infections
- Trial name
- NCT07013864
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Psoriasis Vulgaris
Oral Chinese Herbal Medicine for Psoriasis Vulgaris With Blood Stasis Syndrome
We designed this study as a multicenter, randomized, double blinded and placebo-controlled clinical trial. The aim of the study is to evaluate the clinical efficacy, safety and control of recurrence rate of psoriasis with blood…
- Trial name
- NCT03942198
- Testing
- Taodan Granules
- Where
- 5 sites in China
- Volunteers
- 216 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Comparison of the Efficacy of Saccharomyces Boulardii and Rifaximin in the Treatment of Small Intestinal Bacterial Overgrowth
This multicenter randomized controlled study aims to systematically evaluate the efficacy and safety of Saccharomyces boulardii sachets versus rifaximin in the treatment of small intestinal bacterial overgrowth (SIBO), with a…
- Trial name
- NCT07815548
- Testing
- Saccharomyces boulardii sachets, Rifaximin (Xifaxan)
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Shandong University
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD)
Indiana University Gastrointestinal Motility Diagnosis Registry
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions.
- Conditions
- Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Functional Vomiting
- Trial name
- NCT04506593
- Testing
- no intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Age-related Macular Degeneration
A Phase Ⅱ Clinical Study of Sanhuangjingshimingwan in Wet( Neovascular)Age-related Macular Degeneration(wAMD) Subjects
The study is to evaluate the efficacy and safety of Sanhuangjingshimingwan in Wet AMD.
- Trial name
- NCT04486963
- Testing
- Sanhuangjingshimingwan
- Where
- 6 sites in China
- Volunteers
- 78 people
- Sponsor
- Tasly Pharmaceutical Group Co., Ltd
Irritable Bowel Syndrome
EFESO - EFficacy Enterogermina Small Intestinal Bacterial Overgrowth
Primary objective: to assess the efficacy of Bacillus clausii versus metronidazole in the eradication of the small intestinal bacterial overgrowth, 30 days after the end of treatment.
- Trial name
- NCT00331994
- Testing
- Bacillus clausii, Metronidazole
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Sanofi
Ischemic Stroke
Efficacy and Safety of Qizhitongluo Capsule in the Recovery Phase of Ischemic Stroke
This is a 20-week study consisting of a 12-week multicenter, randomized,double-blind adaptive study to compare efficacy and safety of Qizhitongluo Capsule,Naoxintong Capsule and placebo in the recovery phase of ischemic stroke…
- Trial name
- NCT01762163
- Testing
- Qizhitongluo Capsule, Naoxintong Capsule, Aspirin Enteric-coated Tablets
- Where
- 13 sites in China
- Volunteers
- 622 people
- Sponsor
- China Academy of Chinese Medical Sciences
Enterobacteriaceae Infections
Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae
The continuous increase in the bacterial resistance rate and the slow arrival of new therapeutic options have turned into an antibiotic crisis.
- Trial name
- SIMPLIFY (NCT02795949)
- Testing
- Antipseudomonal beta-lactam antibiotic, De-escalation(short-spectrum antibiotic)
- Where
- 21 sites in Spain
- Volunteers
- 344 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Ischemic Heart Failure
A Clinical Research of Qi Deficiency and Blood Stasis Syndrome (Different Disease With Syndrome)
The main purpose of this research is to reveal the curative effect mechanism of Yiqihuoxue prescription which treat the disease of qi deficiency and blood stasis.
- Trial name
- NCT02875639
- Testing
- Yiqi prescription, Huoxue prescription, Buyang huanwu decoction
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Zhu Mingjun