Clinical trials: Balance; Disorder, Fluid
Oligohydramnios, Amniotic Fluid; Disorder
Effect of Intermittent Pneumatic Compression Device of Lower Limbs in Oligohydramnios
the study will examine the effect of application of intermittent pneumatic pressure device on lower limbs on the amniotic fluid amount and fetal doppler indices in women with oligohydramnios
- Trial name
- NCT05474326
- Testing
- intermittent pneumatic pressure device (Kendall SCD™ 700 Smart Compression™ System)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Critical Illness
Perioperative Fluid Management in Patients Receiving Major Abdominal Surgery - Effects of Normal Saline Versus an Acetate Buffered Balanced Infusion Solution on the Necessity of Catecholamines for Cardiocirculatory Support
Background Intraoperative hypotension is a common problem that significantly contributes to perioperative mortality and morbidity.
- Trial name
- KATECHOL (NCT02414555)
- Testing
- vasopressor, fluid bolus, oesophagus doppler (CardioQ)
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Colorectal Cancer, Postoperative Complications
Bioelectrical Impedance Analysis for Perioperative Fluid Evaluation in Colorectal Cancer Surgery
This study evaluates the usefulness of bioelectrical impedance analysis (BIA) for perioperative fluid evaluation and prediction of postoperative complications in oncological patients undergoing colorectal surgery.
- Conditions
- Colorectal Cancer, Postoperative Complications, Fluid Imbalance
- Trial name
- NCT07404527
- Testing
- Bioelectrical Impedance Analysis
- Where
- Slovenia
- Volunteers
- 85 people
- Sponsor
- Institute of Oncology Ljubljana
Critical Illness, Fluid Overload
Fluid Balance and Body Weight Changes in Critically Ill Adult Patients
Positive fluid status has been consistently associated with worse prognosis in critically ill adult patients.However, observational studies showed poor agreement between fluid balance and body weight changes.
- Trial name
- NCT04434079
- Testing
- Regular critical care
- Where
- Brazil
- Volunteers
- 98 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
C.Surgical Procedure; Cardiac, Right-Sided Heart Failure
Evaluation of Monitoring TECHNOlogies in the PERI-OPerative Care of Cardiac Surgical Patients
The purpose of this prospective observational cohort study is to evaluate multimodal monitoring technologies in the perioperative care of cardiac surgical patients.
- Conditions
- C.Surgical Procedure; Cardiac, Right-Sided Heart Failure, Acute Kidney Injury, Respiratory Insufficiency
- Trial name
- TechnoPeriOp (NCT02658006)
- Testing
- Cardiac surgery
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Montreal Heart Institute
Fluid Overload, Water Electrolyte Imbalance
The Effect of Crystalloids and Colloids on Visceral Blood Flow
Patients often require fluid replacement during and after an operation. This is usually given through veins in the arm using an intravenous cannula and doctors have traditionally used fluid containing sodium chloride (saline).
- Conditions
- Fluid Overload, Water Electrolyte Imbalance, Acid Base Imbalance
- Trial name
- NCT01087853
- Testing
- Crystalloid, Colloid
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Fluid Retention, Fluid Loss
The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration
The purpose of this research study is to evaluate the effects of a topical sodium bicarbonate lotion on physiological and psychological responses associated with hydration status and fluid balance in humans during passive heat…
- Conditions
- Fluid Retention, Fluid Loss, Sodium Retention, Cognitive Change
- Trial name
- AMPlify (NCT04598386)
- Testing
- PR Lotion - AMP Human Performance
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Colorectal Cancer, Colectomy
Randomised Trial of Doppler-Optimised Fluid Balance in Elective Colectomy
Perioperative fluid management has been historically dictated by outdated, contradictory concepts. Excessive or inadequate fluid administration around surgery is deleterious and hence goal-directed fluid therapy using Oesophageal…
- Conditions
- Colorectal Cancer, Colectomy, Surgery, Perioperative Care
- Trial name
- NCT00911391
- Testing
- Oesophageal Doppler, Intraoperative fluid restriction
- Where
- 2 sites in New Zealand
- Volunteers
- 85 people
- Sponsor
- University of Auckland, New Zealand
Critically Ill, Intra-Abdominal Hypertension
The Influence of Fluid Removal Using Continuous Venovenous Hemofiltration (CVVH) on Intra-abdominal Pressure and Kidney Function
Intra- abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are a cause of organ dysfunction in critically ill patients.
- Conditions
- Critically Ill, Intra-Abdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury
- Trial name
- NCT01077895
- Testing
- CVVH, ultrafiltration, ultrafiltration control group
- Where
- 2 sites in Belgium
- Sponsor
- University Hospital, Ghent
Fluid Volume Disorder
Effects of Hypertonic Saline-HES Solution on Extracellular Water in Cardiac Surgery Patients
The aim of the study is to describe the effects of hypertonic saline/hydroxyethylstarch solution in comparison to saline solution for 25 + 25 patients undergoing coronary bypass grafting surgery (CABG) using CPB.
- Trial name
- NCT01348659
- Testing
- 7.2% NaCl/hydroxyethylstarch, NaCl 0.9%
- Where
- Finland
- Volunteers
- 48 people
- Sponsor
- Kati Järvelä
Wounds and Injuries, Multiple Trauma
Normal Saline Versus Plasmalyte in Initial Resuscitation of Trauma Patients
The purpose of this study is to determine whether an intravenous salt solution called "Plasmalyte" causes less abnormality of the body's acid levels than a solution called "Normal Saline."
- Conditions
- Wounds and Injuries, Multiple Trauma, Disorder of Fluid Balance
- Trial name
- NCT01270854
- Testing
- Plasmalyte A, Normal Saline
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of California, Davis
Acid-Base Balance Disorder
Comparison of Plasmalyte A, Normal Saline and Ringer Lactate as Intraoperative Fluid During Renal Transplantation
Fluid management being an important component of surgery becomes more challenging for an anesthesiologist in case of renal transplant.
- Trial name
- NCT03115060
- Testing
- intravenous fluid administration WITH NORMAL SALINE, PLASMALYTE A, OR RINGER LACTATE
- Where
- India
- Volunteers
- 105 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Dehydration
Fluid Balance During Exercise in the Heat With Water, Flavored Placebo, or a Carbohydrate-electrolyte Beverage Intake (The APEX Study)
The purpose of the APEX study is to determine whether carbohydrate-electrolyte beverage intake promotes fluid balance during exercise in the heat compared with water or placebo intake.
- Trial name
- APEX (NCT01893853)
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Inflammatory Bowel Diseases, Short Bowel Syndrome
Effects of an Amino Acid Mixture on Gastrointestinal Function, Inflammation and Fluid Balance: A Pilot Study in Patients With Inflammatory Bowel Disease
This pilot study will examine the benefit of this amino acid based hydration solution in patients with IBD who have undergone a total colectomy and have either ileostomies or jpouches.
- Conditions
- Inflammatory Bowel Diseases, Short Bowel Syndrome, Ileostomy - Stoma
- Trial name
- NCT03451253
- Testing
- amino acid mixture beverage, glucose-based sports drink
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Entrinsic Bioscience Inc.
Haemodiafiltration, Haemodialysis
Adequacy of Haemodiafiltration: Middle Molecules Clearance, Patients Reported Outcomes and Sodium Balance
The goal of this observational study is to understand the differences in terms of middle molecules clearance and patient outcomes in High (>23Litres (L)) vs Low (<23 L) convection volume (CV) Hemodiafiltration (HDF) and to…
- Conditions
- Haemodiafiltration, Haemodialysis, Patient Reported Outcome Measurements, Nutrition
- Trial name
- NCT07717255
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- East and North Hertfordshire NHS Trust
Acid-Base Imbalance, Respiratory Alkalosis
Cerebrospinal Acid-base in Pregnant and Non-pregnant Fertile Women
The third trimester of pregnancy is typically characterized by the development of a marked respiratory alkalosis. The possible role of pregnancy-induced variations of cerebrospinal fluid (CSF) acid-base characteristics on the…
- Conditions
- Acid-Base Imbalance, Respiratory Alkalosis, Cerebrospinal Fluid, Pregnancy
- Trial name
- NCT03496311
- Testing
- Acid - Base characterization
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Brain Edema, Metabolic Disturbance
Effect of Mannitol 20% Versus Hypertonic Saline 7.5% in Brain Metabolism and Oxygenation
Usage of osmotic agents is a standard practice in neuroanesthesia since cerebral edema is a very common situation for patients with pathology in the brain.
- Conditions
- Brain Edema, Metabolic Disturbance, Electrolyte and Fluid Balance Conditions
- Trial name
- NCT03573999
- Testing
- Mannitol, NaCl 7.5%
- Where
- 2 sites in Greece
- Volunteers
- 54 people
- Sponsor
- Aristotle University Of Thessaloniki
Critical Illness
Fluid Management in Patients Undergoing Cardiac Surgery
Background: Currently used crystalloid solutes have a variable composition and may therefore influence acid-base status, intra- and extracellular water content and plasma electrolyte compositions and have a major impact on organ…
- Trial name
- Hemacetat (NCT02895659)
- Testing
- perioperative hemodynamic management with vasoactive medications (norepinephrine, adrenaline ect)
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cancer, Oedema
Measuring Fluid Buildup in Cancer Patients
The goal of this study is to improve the monitoring of fluid retention in cancer patients. The main question it aims to answer is: Can segmental bioelectrical impedance analysis be used to monitor local fluid retention (edema) in…
- Conditions
- Cancer, Oedema, Bioelectrical Impedance, Lymphoedema
- Trial name
- NCT07443618
- Where
- Denmark
- Volunteers
- 46 people
- Sponsor
- Jens Rikardt Andersen
Brain Neoplasms
Fluid Therapy During Brain Tumor Resection in Children
Fluid management of children during neurosurgery is not well established. Hypotonic solutions, commonly still used in pediatric patients, may enhance cerebral edema and worse operative conditions.
- Trial name
- NCT02707549
- Testing
- balanced crystalloid solution (components: sodium chloride, sodium gluconate, sodium acetate, potassium chloride and magnesium chloride), 0.9% sodium chloride
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Federal University of São Paulo