Clinical trials: Balance
ADME, Healthy
A Study to Evaluate the Mass Balance of 14C-Napabucasin in Healthy Adult Male Subjects
This is a Phase I, single-center, open-label, single-sequence, study evaluating the absorption, metabolism, and excretion of napabucasin in healthy adult male volunteers using a mixture 14C-radiolabeled and unlabeled material.
- Trial name
- NCT03525405
- Testing
- napabucasin
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sumitomo Pharma America, Inc.
Core Muscle Weakness, Postural Control Deficit
"CORE Training for Musculoskeletal Health: A Study on Adaptive Exercise Protocols"
This study aims to evaluate the effects of an adaptive core training protocol that integrates core stability, core strength, and high-intensity core power exercises on muscle activation, hypertrophy, balance, and quality of life.
- Conditions
- Core Muscle Weakness, Postural Control Deficit, Trunk Stability Impairment, Functional Performance Limitation
- Trial name
- RCT-EMG-US-QoL (NCT07025395)
- Testing
- - Core Training Protocol, Control Group Core Routine
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ioannis Tsartsapakis
Osteoarthritis, Knee, Mobility Limitation
Effects of Improved Calf Muscle Function on Gait, Balance and Joint Loading in Older Adults
This study investigates the role of calf muscle function in gait performance, balance and knee joint loading. Previous studies have linked age-related loss of calf muscle function with impairments in gait performance and balance…
- Conditions
- Osteoarthritis, Knee, Mobility Limitation, Accidental Fall
- Trial name
- NCT03921801
- Testing
- Gait retraining, Gait retraining + strength training
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Circuit-Based Exercise, Exercise Test
Effects of Circuit Training Combine With Square-Stepping Exercise, Strength Training and Balance Training on Senior Fitness and Fall Risk in Elderly in the Community
According to the cause of death statistics compiled by the Ministry of Health and Welfare in 2022, among the causes of death among the elderly, falls ranked second among the causes of death from accidental injuries over the age…
- Conditions
- Circuit-Based Exercise, Exercise Test, Community Health Nursing, Aged
- Trial name
- SSE (NCT06358170)
- Testing
- Circuit Training Combine with Square-Stepping Exercise
- Where
- Taiwan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hsin-ching, Tsai
Elderly, Exercise
The Effect of Kinetic Brain Exercises on Balance and Dual Task Activities in the Elderly
The aim of the study is to evaluate the balance and dual-task activities of Kinetic Brain Exercises in healthy elderly individuals living in nursing homes.
- Trial name
- NCT06400953
- Testing
- Kinetic Brain Exercises and Core Stabilization Exercises, Core Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Healthy Volunteers
Effect of Ration Formulations on Warfighter Energy Balance and Physical Performance During a Field Training Exercise
The goal of this randomized clinical trial is to determine the effects of consuming the Close Combat Assault Ration (CCAR) compared to the First Strike Ration (FSR) during a 7-day strenuous military training on energy intake and…
- Trial name
- NCT06261437
- Testing
- CCAR, FSR
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Hyponatremia
Influence of Triathlon on the Electrolyte Balance
Aim of the study is examining the incidence of the occurrence of hyponatremia during a Triathlon
- Trial name
- Ironman (NCT02263586)
- Testing
- Education in nutrition
- Where
- Germany
- Volunteers
- 1,089 people, healthy volunteers welcome
- Sponsor
- University Hospital of Cologne
Asthma
Airway Smooth Muscle and Asthma Severity
Our hypothesis is that the severity of asthma is determined by the way in which airway smooth muscle cells grow and release inflammatory mediators.
- Trial name
- NCT00779870
- Testing
- bronchoscopy
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Healthy
Bioequivalence Study of Ramipril 10 mg Capsules Under Fed Conditions
The study was conducted as an open label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover bioavailability study comparing ramipril 10 mg capsules of Ohm Laboratories Inc., with Altace®…
- Trial name
- NCT00879788
- Testing
- Ramipril 10mg capsules
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Healthy
Bioequivalence Study of Sertraline Hydrochloride Tablets 100 mg in Fed Conditions
The objective of this study was to compare and evaluate the single-dose oral bioavailability of the test formulation of Sertraline Hydrochloride 100 mg tablets (Dr.
- Trial name
- NCT01267383
- Testing
- Sertraline
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Energy Balance,, Appetite,
Effect of Exercise With or Without Breakfast, on Metabolism, Appetite and Cognition
The purpose of this study is to assess the effect of eating breakfast in combination with exercise on fat usage, appetite and brain performance later in the day.
- Conditions
- Energy Balance,, Appetite,, Cognitive Function.
- Trial name
- NCT01229345
- Testing
- Breakfast & exercise
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Dry Eye Disease
Vizol S Lipid Balance Efficacy and Safety Study in Patients With Dry Eye
The clinical investigation was intended to investigate the efficacy, ocular tolerability and safety of Vizol S Lipid Balance, a new eye drops, emulsion developed by JADRAN - GALENSKI LABORATORIJ d.d., in patients with moderate to…
- Trial name
- NCT06323395
- Testing
- Vizol S LIPID BALANCE eye drops, ophthalmic saline eye drops
- Where
- 2 sites in Serbia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Jadran Galenski laboratorij d.d.
Healthy Participants
Study to Investigate the Mass Balance, Metabolism, and Excretion of [14C]PF-07321332 in Healthy Male Participants.
This study is to characterize mass balance and further the understanding of human pharmacokinetics, metabolism, and excretion of radiolabeled [14C]PF-07321332 in healthy male participants following oral administration with…
- Trial name
- NCT05178654
- Testing
- [14C]PF-07321332
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Volunteers
Pharmacokinetic and Mass Balance Study of Oral-Administrated [14C]-DZD9008 in Healthy Male Subjects
This is a phase 1, open-label, ADME study with single oral administration of [14C]-DZD9008 in healthy subjects.
- Trial name
- NCT05159895
- Testing
- [14C]-DZD9008
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Dizal Pharmaceuticals
Obesity
Characterization of Brachial Arterial t-PA Release, Endothelial Function, Obesity and Inflammation
T-PA release is impaired in obese subjects. In order to have a better mechanistic understanding of t-PA release, we will compare t-PA release to Flow Mediated Vasodilation, Radial Artery Tonometry, and other markers of…
- Trial name
- P1A3B (NCT00780481)
- Testing
- Bradykinin
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Tuberculosis
Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009)
This will be a Phase 1, single-center, randomized, balanced, single-dose, two-period, two-sequence, crossover, open-label study to evaluate the effect of food on the pharmacokinetics of PA-824.
- Trial name
- CL-009 (NCT01830439)
- Testing
- PA-824 200mg, PA-824 50mg
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Global Alliance for TB Drug Development
Type 2 Diabetes
Assessment of Cognitive Function and Functional Performance in Patients With Type 2 Diabetes
Diabetes is a chronic metabolic disease that is becoming a growing public health problem worldwide, affecting people's lives in many ways.
- Trial name
- NCT07390292
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Healthy
Bioequivalence Study of Atorvastatin Calcium Tablets, 80 mg of Dr. Reddy's Under Fasting Conditions
The purpose of this study is to compare and evaluate the single-dose oral bioavailability and to monitor the safety of subjects.
- Trial name
- NCT01645449
- Testing
- Atorvastatin Calcium Tablets, 80 mg
- Where
- Germany
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Spinal Cord Injuries (SCI), Paraplegia and Tetraplegia
Self-balancing Personal Exoskeleton for SCI (Site 2)
This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).
- Trial name
- NCT06814015
- Testing
- Hands-free exoskeleton
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Healthy
Bioequivalence Study of Tetrabenazine Tablets 25 mg Under Fed Conditions
This is an open-label, randomized, four-period, two-treatment, two-sequence, balanced, single dose, crossover, oral bioequivalence study in healthy, adult, human subjects under fed conditions.
- Trial name
- NCT03702855
- Testing
- Tetrabenazine Tablets 25 mg
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
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