Clinical trials: Balanced
Impaired Mobility, Impaired Balance
Usability Evaluation of the Safer Seat
This is an initial usability assessment of a vehicle Seat Transfer device, the Safer Seat. The study will involve target end users (individuals with mobility impairments) trialing the Safer Seat and providing feedback via the…
- Trial name
- NCT07011446
- Testing
- Safer Seat Usability Trial
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Julie Faieta
Cerebral Palsy, Postural; Defect
The Effect of Dynamic Elastomeric Fabric Orthosis (DEFO) on Sitting Balance and Gross Manuel Dexterity in Cerebral Palsy
To evaluate the effects and feasibility of lycra based compression garment called Stabilizing Pressure Input Orthosis (SPIO) vest on posture and balance during sitting and gross manuel dexterity, parent satisfaction with the…
- Trial name
- NCT03191552
- Testing
- SPIO, conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Marmara University
Diabetes Mellitus, Type 2
To Bathe or Not to Bathe
Type 2 diabetes mellitus (T2DM) is characterised by chronic high blood sugar concentration (hyperglycaemia) and insulin resistance leading to a reduction in insulin sensitivity.
- Trial name
- NCT03798717
- Testing
- Heating
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Portsmouth
Healthy Volunteers
A Study to Evaluate the Mass Balance, Pharmacokinetics (PK), Metabolism and Excretion of TAK-954 Containing Microtracer ([14C]-TAK-954) in Healthy Male Participants
The purpose of this study is to determine the mass balance, routes of elimination and characterize the metabolic profiles of a single intravenous dose of [14C]-TAK-954, identify major circulating and excreted metabolites.
- Trial name
- NCT03500224
- Testing
- [14C]-TAK-954
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Millennium Pharmaceuticals, Inc.
Dry Eye
Clinical Trial to Compare the Safety and Efficacy of Nanodrop®
Study design: Phase I-II clinical trial, comparative, non-inferiority with active control, parallel groups, double blind with randomisation.
- Trial name
- PRO-176/I (NCT04111965)
- Testing
- Nanodrop®, Systane Balance
- Where
- 6 sites in Mexico
- Volunteers
- 126 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Parkinson Disease
Physical Therapy and Deep Brain Stimulation in Parkinson Disease
While deep brain stimulation of the subthalamic nucleus (STN-DBS) is commonly used to reduce tremor, muscle stiffness, and bradykinesia in people with Parkinson disease (PD), preliminary studies suggest balance may worsen and…
- Trial name
- PTDBS (NCT03181282)
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Washington University School of Medicine
Obesity &Amp; Overweight, General Anesthetic
Postoperative Opioid Consumption in Gastric Sleeve Surgery
The study aimed to compare balanced anesthesia protocols using only opioids as analgesics during induction in gastric sleeve surgery with protocols using opioids and ketamine together in terms of anesthesia management, opioid…
- Conditions
- Obesity &Amp; Overweight, General Anesthetic, Ketamine
- Trial name
- POCiGSS (NCT07135154)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Balikesir University
Multiple Sclerosis
Cerebellar tDCS and Balance Training in PwMS
Many people with multiple sclerosis (PwMS) have decreased balance and postural control, gait deficits, and a high frequency of falls.
- Trial name
- NCT04391023
- Testing
- Balance Training, 2 mA Transcranial Direct Current Stimulation, 4 mA Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Iowa
Immunogenicity, Healthy Volunteers
Comparative Immunogenicity Study of Multiple Doses of Proposed Pegfilgrastim Biosimilar, INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects.
The study was an assessor-blind, balanced, parallel, randomized, two-treatment, comparative immunogenicity study of multiple doses of subcutaneous (SC) Pegfilgrastim injection (6 mg/0.6 mL; Intas Pharmaceuticals Ltd.
- Trial name
- NCT04015232
- Testing
- INTP5, US Neulasta
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Intas Pharmaceuticals, Ltd.
Healthy
Assess the Effect of Zolpidem, Silenor & Placebo on Arousability, Ataxia/Balance & Cognition in Healthy Volunteers
This is a Phase IV, randomized, double-blind, placebo-controlled, four-arm crossover study. The study will assess the effects of a single dose of Silenor 6 mg compared with matching placebo and a single dose of zolpidem 10 mg…
- Trial name
- NCT02353299
- Testing
- Silenor 6 mg, zolpidem 10 mg
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Currax Pharmaceuticals
Dry Eye
Subjective and Objective Performance of Systane Complete Multi-Dose PF Versus Walgreen's Lubricant Balance
Single site, prospective, double-masked, randomized-controlled, two-arm study of the dry eye symptoms as well as corneal and conjunctival staining in subjects using 2 different eyedrops.
- Trial name
- NCT06219577
- Testing
- Systane Complete Multi-Dose PF, Walgreen's Lubricant Balance
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Scripps Poway Eyecare and Optometry
Healthy
Copper Balance in Healthy Participants Administered ALXN1840
The study will assess the change from baseline in mean daily copper balance in healthy participants with repeat-dose administrations of ALXN1840 over 2 weeks.
- Trial name
- NCT04594252
- Testing
- ALXN1840
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Alexion Pharmaceuticals, Inc.
Balance Disorder
Vestibular Intervention Via Portable Electrical Stimulator (VIPES)
The purpose of this study is to develop a vestibular interventional approach using stochastic vestibular stimulation (SVS) through a small, lightweight device, and a comfortable electrode set on the back of the head that…
- Trial name
- NCT04968197
- Testing
- Vestibular Intervention via Portable Electrical Stimulator (VIPES) system
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Mayo Clinic
Cataracts
Comparison of Centurion® Vision System With Balanced Tip and the Infiniti® Vision System With the Mini Flared Kelman (MFK) Tip During Cataract Extraction Surgery of Hard Lenses
The purpose of this study is to demonstrate that the Centurion® Vision System (CVS) used with the 45° Balanced Tip will result in less Cumulative Dissipated Energy (CDE) than the lnfiniti® Vision System (IVS) used with the 45°…
- Trial name
- NCT02502526
- Testing
- Centurion® Vision System, 45° Balanced Tip, Centurion® Vision System, 45° MFK Tip, lnfiniti® Vision System, 45° MFK Tip
- Volunteers
- 231 people
- Sponsor
- Alcon Research
Seated Treadmill Training, Treadmill Locomotor-based Training
Ankle Robotics Training After Stroke
Veterans and other Americans who survive stroke often face disabling motor impairments that impede performance of activities of daily living and limit free-living activity.
- Conditions
- Seated Treadmill Training, Treadmill Locomotor-based Training, Treadmill Only
- Trial name
- NCT01337960
- Testing
- Seated Robot Training (SRT), Treadmill Locomotor-based Training (TMR), Treadmill Only (TMO)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- US Department of Veterans Affairs
Chronic Disease
Measuring the Implementation of the LiFE Program in Primary Care for Older Adults Aged 75 Years or Older
The goal of this study is to evaluate how to implement an evidence-based lifestyle-integrated strength and balance exercise (LiFE) intervention in primary care to promote increased physical activity (PA) and improvements in…
- Trial name
- Mi-LIFE (NCT02266225)
- Testing
- Lifestyle-integrated Functional Exercise
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Edentulous Mouth, Edentulous Jaw
Canine Guidance vs Bilateral Balanced Occlusion in Complete Denture
The objective of this study is to compare the canine guidance (CG) and bilateral balanced occlusion (BBO) on denture satisfaction and kinesiographic parameters of complete denture wearers, by means of a cross-over trial.
- Trial name
- NCT01420536
- Testing
- Occlusal scheme
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Parkinson Disease
Modulation of GABA-A Receptors in Parkinson Disease-Transdermal Flumazenil Arm
The arm of this study evaluates possible GABA-A receptor target engagement effects of the FDA-approved medication, transdermal flumazenil (added 4/2020, replaced clarithromycin), in the setting of Parkinson's disease.
- Trial name
- GABA-A (NCT03440112)
- Testing
- Clarithromycin (Not used as of 4/2020), Transdermal flumazenil (Added 4/2020)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Nicolaas Bohnen, MD, PhD
Chronic Kidney Disease
Calcium and Phosphorus Balance and Calcium Kinetics in Patients With Stage 3/4 Chronic Kidney Disease
The purpose of this study is to gain a better understanding of calcium absorption and metabolism in patients with Chronic Kidney Disease (CKD) using calcium balance and kinetic methods.
- Trial name
- NCT01161407
- Testing
- 1500 mg/d elemental calcium as calcium carbonate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Indiana University
Huntington's Disease
Impact of Xenazine(Tetrabenazine)on Gait and Functional Activity in Individuals With Huntington's Disease
In individuals with Huntington's disease (HD), chorea may contribute to balance problems and difficulties with walking, sit to stand transfers and stair climbing that in turn may contribute to high fall rates.
- Trial name
- NCT01451463
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Ohio State University