Clinical trials: Bariatric Sleeve Gastrectomy
Visceral Pain, Bariatric Surgery Candidate
Paragastric Autonomic Blockade to Prevent Visceral Pain After Laparoscopic Sleeve Gastrectomy
Visceral pain (VP) following laparoscopic sleeve gastrectomy remains a substantial problem. VP is associated with autonomic symptoms, especially nausea and vomiting, and is unresponsive to traditional pain management algorithms…
- Conditions
- Visceral Pain, Bariatric Surgery Candidate, Pain, Postoperative, Vomiting, Postoperative
- Trial name
- PG-ANB (NCT05353426)
- Testing
- Paragastric autonomic neural blockade
- Where
- Colombia
- Volunteers
- 145 people
- Sponsor
- Universidad Simón Bolívar
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Grade III Obesity, Type 2 Diabetes Mellitus
Metabolic Changes After Bariatric Surgery
Literature data clearly demonstrate that treatment of obese patients is very expensive, long and achieve weight loss may not be permanent, and regardless of whether the treatment dominated diet therapy, physical activity, or…
- Trial name
- NCT02893891
- Testing
- Laparoscopic sleeve gastrectomy, Laparoscopic gastric plication, Intragastric balloon
- Where
- 2 sites in Czechia
- Volunteers
- 150 people
- Sponsor
- University Hospital Ostrava
Bariatric Surgery Candidate, Glucose Metabolism Disorders
The Importance of Ghrelin for Glucose Metabolism After Sleeve Gastrectomy
The overall aim is to delineate the contribution of ghrelin to glucose tolerance after sleeve gastrectomy. The hypothesis is that decreased concentration of ghrelin after SG is of importance for improved insulin secretion and…
- Trial name
- NCT05189353
- Testing
- Ghrelin
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Nutritional Deficiency
Nutritional Deficiency After Bariatric Surgeries
comparing micro-nutrient deficiencies in postoperative morbid obese patients who will be undergoing gastric bypass and sleeve gastrectomy with regards to vit B 12, vitamin D,iron studies and calcium .
- Trial name
- NCT04717973
- Testing
- laboratory testing of CBC, serum ferritin, and vitamin B 12
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Osteoarthritis of Knee, Arthroplasties, Knee Replacement
Morbid Obesity and Severe Knee Osteoarthritis - Which Should Be Treated First?
The goal of this study is to determine whether undergoing bariatric surgery before knee replacement leads to better outcomes compared to undergoing knee replacement before bariatric surgery.
- Conditions
- Osteoarthritis of Knee, Arthroplasties, Knee Replacement, Sleeve Gastrectomy
- Trial name
- NCT06767787
- Testing
- laparoscopic sleeve gastrectomy, total knee arthroplasty
- Where
- 2 sites in Canada
- Volunteers
- 142 people
- Sponsor
- Memorial University of Newfoundland
Overweight and Obesity, Bariatric Surgery Candidate
Intraperitoneal Local Anesthetic in Bariatric Surgery Study (iLABS Study)
Obesity is a metabolic disorder that has gradually become a prevalent public health problem and is becoming one of the leading causes of death and disability worldwide.
- Trial name
- NCT03175081
- Testing
- Ropivacaine, Normal saline
- Where
- 2 sites in Malaysia
- Volunteers
- 54 people
- Sponsor
- Dr. Tikfu Gee
Bariatric Surgical Procedures, Anesthesia and Analgesia
Comparison of Abdominal Plane Blocks in Postoperative Pain Control in Patients Undergoing LSG
The goal of this prospective observational study is compare in terms of efficiency and complications transversus abdominis plane (TAP) and Modified thoracoabdominal plane block-perichondrial approach (M-TAPA) blocks in patients…
- Conditions
- Bariatric Surgical Procedures, Anesthesia and Analgesia, Anesthesia, Regional
- Trial name
- NCT06201546
- Testing
- TAP block group, m-TAPA block group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pain, Postoperative
Effect of Preincisional Bupivakain Infiltration on Postoperative Narcotic Medication Requirement
Postoperative pain and use of narcotic analgesics after laparoscopic bariatric surgeries are problems that need to be solved in terms of patient comfort.
- Trial name
- NCT03071991
- Testing
- study group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Obesity
Controlled Trial Evaluating the Efficacy of Protein Supplementation in the Short Term After Bariatric Surgery
The main objective will be to evaluate the effect at 5 weeks of nutritional management associated with protein supplementation (adapted to the post-operative period) on the maintenance of lean body mass at the whole body in obese…
- Trial name
- PROTISLEEVE (NCT02712086)
- Testing
- protein supplementation
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Obesity, Bariatric Surgery Candidate
Preoperative Use of a Magnetically Controlled Capsule Endoscopy in Patients Undergoing Bariatric Surgery
The goal of this clinical trial is to test if a swallowable camera capsule can safely examine the upper digestive tract in people preparing for weight loss surgery.
- Conditions
- Obesity, Bariatric Surgery Candidate, Hypertension, Diabetes
- Trial name
- NAVICAM (NCT07587437)
- Testing
- Magnetically Controlled Capsule Endoscopy (MCCE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jerry Dang
Morbid Obesity
Glucose Homeostasis Pre and Post Bariatric Surgery
The investigators wish to study the effects of three forms of bariatric surgery: Roux-en-Y gastric bypass, Sleeve Gastrectomy, and Gastric Banding. The surgery is not part of the clinical trial.
- Trial name
- RB (NCT00981500)
- Testing
- gastric bypass, gastric banding, sleeve gastrectomy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Calcium Metabolism Disorders, Morbid Obesity
Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton
In this pre-post observational study, the investigators will enroll and follow a cohort of about 50 adults undergoing sleeve gastrectomy surgery for weight loss.
- Trial name
- NCT02778490
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
Bariatric Surgery Candidate
Ultrasonograpahic Evaluation of Diaphragmatic Functions in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy
Major laparoscopic sleeve gastrectomy surgery requires steep Trendelenburg position with pneumoperitoneum for a long time leading to decrease pulmonary compliance and lung volumes due to cephalic displacement and decrease…
- Trial name
- NCT04130217
- Testing
- addition of positive end expiratory pressure in ventilated patients, addition of positive end expiratory pressure and recruitment maneuver in ventilated patients
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Zagazig University
Obese Patients (BMI ≥ 30 kg/m²), Obese Patients
Modifications to Gastric Sleeve: Implications for GRED and Quality of Life
This is a prospective randomized clinical trial evaluating the impact of antrum and fundus calibration during laparoscopic vertical gastrectomy (VG) on postoperative gastroesophageal reflux disease (GERD), quality of life, and…
- Conditions
- Obese Patients (BMI ≥ 30 kg/m²), Obese Patients, Obese Patients With Bariatric Surgery, Obese With Comorbidities
- Trial name
- NCT07070908
- Testing
- Antrum calibration, Fudus calibration, No antrum calibration
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital San Juan de Dios Tenerife
Skeletal Muscle, Bariatric Surgery
Circulating Muscle-specific microRNAs and Renal, Nutritional and Inflammatory Biomarkers of Skeletal Muscle Loss During the First 18 Months After Laparoscopic Sleeve Gastrectomy
Metabolic and bariatric surgery produces substantial and durable weight loss, but a considerable proportion of that loss is not adipose tissue.
- Trial name
- NCT07806513
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Obesity
Effect of GLP-1 Receptor Agonism After Sleeve Gastrectomy
Observational studies suggest that bariatric surgery is the most effective intervention for weight loss. Comparative effectiveness of Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) demonstrate that RYGB is…
- Trial name
- NCT03115424
- Testing
- Saxenda, RYGB
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Bariatric Surgery Candidate, Cholelithiases
Multicenter Cohort of 768 High-risk Patients With Symptomatic Gallstones, Adding Cholecystectomy Did Not Increase Length of Stay or Perioperative Morbidity, Supporting it as a Safe Single-stage Option
Despite numerous single-center reports and meta-analyses, few studies have directly compared outcomes of LSG with versus without concomitant cholecystectomy exclusively in a high-risk cohort as defined above.
- Trial name
- NCT07772440
- Volunteers
- 2,512 people
- Sponsor
- Zagazig University