Clinical trials: Bariatric Surgeries
Severe Obesity, Hypoxia
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures
The study evaluated the effect of non-invasive positive pressure ventilation (NIPPV) to decrease the incidence of desaturation events in patients with severe obesity undergoing upper endoscopy.
- Trial name
- NCT03529461
- Testing
- Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bristol Hospital
Obesity
Psychopathology, Disordered Eating, and Impulsivity as Predictors of Outcomes of Bariatric Surgery
This study will evaluate the relationship between psychopathology, disordered eating, and impulsivity (measured by clinical interview, self-report measures, and objective testing) on changes in weight and psychosocial status in…
- Trial name
- SIDE-BAR (NCT02775071)
- Volunteers
- 300 people
- Sponsor
- University of Pennsylvania
Morbid Obesity
Bariatric Embolization of Arteries for the Treatment of Obesity
The purpose of this study is evaluate the safety and effectiveness of bariatric embolization as a minimally-invasive image-guided procedure for morbid obesity.
- Trial name
- BEAT Obesity (NCT02165124)
- Testing
- Artificial Embolization Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Obesity
Study for Short Term Weight Loss in Candidates for Bariatric Surgery
The purpose of this study is to determine whether the GI Endobarrier Liner is safe and effective.
- Trial name
- NCT00985491
- Testing
- Endobarrier Liner
- Where
- Chile
- Volunteers
- 46 people
- Sponsor
- Morphic Medical Inc.
Arterial Embolization, Other Surgical Procedures
Gastric Artery Embolization Trial for Lessening Appetite Nonsurgically
The purpose of this pilot study is to achieve the collection of safety and efficacy data in patients undergoing left gastric artery embolization for morbid obesity in the United States.
- Conditions
- Arterial Embolization, Other Surgical Procedures, Obesity
- Trial name
- GETLEAN (NCT02248688)
- Testing
- BeadBlock 300 - 500 Micron, Left Gastric Artery Embolization
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Dayton Interventional Radiology
Hypoglycemia, Complications of Bariatric Procedures
Delivery of G-Pump™ (Glucagon Infusion) From an OmniPod® to Prevent Hypoglycemia in Post-Bariatric Surgery Patients
The primary objective of this study is to test an optimized control system for sensor-guided (physician administered) delivery of glucagon, and test Proof-of-Concept (POC) in a clinical setting in patients with severe…
- Trial name
- NCT02733588
- Testing
- G-Pump™ (glucagon infusion)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Xeris Pharmaceuticals
Obesity
Multivitamin Adherence Following Bariatric Surgery
Additional micronutrient supplementation is required due to the changes in the gastrointestinal anatomy and physiology following bariatric surgery along with decreased dietary intake and rapid weight loss.
- Trial name
- NCT02124889
- Testing
- Weekly Internet surveys
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences
Type 2 Diabetes
Diabetes and Gastric By- Pass
The purpose of this study is to evaluate the mechanisms leading to rapid postoperative improvement in diabetes following Gastric By-Pass surgery for obesity.We will evaluate and compare the changes in glucose level, beta-cell…
- Trial name
- NCT01153516
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Texas Southwestern Medical Center
Obesity
EMPOWER Clinical Trial: Vagal Blocking for Obesity Control
This is a randomized multi-center study being done to measure the ability of a new medical device, Maestro System, to safely reduce body weight over five years in people who are considered obese.
- Trial name
- EMPOWER (NCT00521079)
- Testing
- Therapy ON, Therapy OFF
- Where
- 15 sites in United States, Australia
- Volunteers
- 294 people
- Sponsor
- ReShape Lifesciences
Obesity, Pain
Intravenous Acetaminophen Use With Bariatric Surgery on Morbidly Obese Patients
Bariatric patients usually require the use of either intravenous or oral opioid medications. The use of opioids, however, is often associated with side-effects such as nausea, sedation pruritus, urinary retention and respiratory…
- Trial name
- NCT01527942
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Trinity Health Of New England
Bariatric Surgery
Gaining Optimism After Weight Loss Surgery (GOALS) I
This study examines the feasibility, acceptability, and preliminary impact of an adapted positive psychology-motivational interviewing (PP-MI) intervention for physical activity among patients who have recently undergone…
- Trial name
- GOALS (NCT04867902)
- Testing
- Positive Psychology-Motivational Interviewing Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Obesity
Exendin-9,39 and Satiety After Bariatric Surgery
The overall aim of the application is to determine the contribution of the elevated incretin hormone concentrations seen after certain types of bariatric surgery to the regulation of food intake and satiety.
- Trial name
- NCT02779075
- Testing
- Saline, Exendin-9,39
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Morbid
Positive Psychology Intervention for Patients Post-bariatric Surgery and Their Partners
The goal of this waitlist-control design, pilot randomized controlled trial is to test feasibility, acceptability, and preliminary efficacy of a remotely-delivered dyadic positive psychology intervention for patients 2 years…
- Trial name
- NCT05958615
- Testing
- Reimagining Us in the Context of Bariatric Surgery (ReConnect)
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Larissa McGarrity, Ph.D.
Obesity
Comparative Effectiveness of Intubating Devices in the Morbidly Obese
This prospective, randomized study will compare the effectiveness of 4 different airway intubating devices which are most commonly used.
- Trial name
- NCT01114945
- Testing
- McGrath, GlideScope, Direct Macintosh Laryngoscopy
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Cedars-Sinai Medical Center
Bariatric Surgery, Obesity
Apixaban Pharmacokinetics in Bariatric Patients (APB)
The Center for Bariatric Surgery is interested in conducting a pharmacokinetic study of apixaban (an oral anticoagulant with FDA approval for use of venous thrombo embolism (VTE) prophylaxis and treatment) in the obese adult…
- Trial name
- APB (NCT02406885)
- Testing
- Apixaban
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Johns Hopkins University
Pain, Postoperative, Postoperative Nausea and Vomiting
Effect of Pulmonary Recruitment Maneuver (PRM) on Pain and Nausea After Laparoscopic Bariatric Surgery
The purpose of this prospective, blinded, randomized clinical trial is to investigate whether a ventilator-piloted PRM at the end of laparoscopic bariatric surgery could reduce overall postoperative pain and nausea.
- Trial name
- NCT03026530
- Testing
- Pulmonary recruitment maneuver, Laparoscopic bariatric surgery, Ventilator
- Volunteers
- 200 people
- Sponsor
- Region Östergötland
Obesity
Dexmedetomidine to Treat Bariatric Surgery-associated Pain
Obesity represents one of the most important public health issues according to the World Health Organization and it has reached epidemic proportions globally.
- Trial name
- NCT02880540
- Testing
- Fentanyl, Morphine, Dexmedetomidine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Janelle Vaughns
Obesity, Morbid
PET Imaging and Bariatric Surgery
The purpose of this study is to look at certain areas of the brain that are related to addictive behaviors, such as overeating. These areas are called 'dopamine type 2 receptors' (DRD2/3) and other studies have shown that obese…
- Trial name
- NCT00801827
- Testing
- F-18 (fallypride)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Vanderbilt University Medical Center
Hypoglycemia, Reactive, Hypoglycemia
Continuous Glucose Monitoring to Reduce Hypoglycemia and Improve Safety After Gastric Surgery
The purpose of this study is to see if the use of a continuous glucose monitor (CGM) by people who experience low blood sugars (hypoglycemia) after gastric surgery can help reduce the number and severity of low blood sugar…
- Trial name
- NCT03353415
- Testing
- Dexcom CGM masked, Dexcom CGM unmasked
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Joslin Diabetes Center