Clinical trials: Bariatric Surgery, open to volunteers
Contraception
Drospirenone Only Pills and Cervical Mucus Changes: A Pre- and Post-Bariatric Surgery Study
The purpose of this study is to study the effect of Drospirenone on cervical mucus change by modified Insler score, pre-bariatric surgery and post-bariatric surgery
- Trial name
- NCT06345586
- Testing
- Drospirenone
- Where
- Thailand
- Volunteers
- 16 people
- Sponsor
- Chulalongkorn University
Obesity, Bariatric Surgery
Establishment of a Classification System and Postoperative Risk Warning Model for Patients Undergoing Bariatric Metabolic Surgery for Severe Obesity
This study aims to establish a classification system for patients undergoing metabolic surgery for severe obesity by constructing a prospective cohort of 2,000 patients and collecting clinical and biological data at multiple time…
- Conditions
- Obesity, Bariatric Surgery, Bariatric Surgery (Sleeve Gastrectomy )
- Trial name
- NCT07093502
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Postoperative Pain, Acute, Postoperative Pain, Chronic
Recovering From Bariatric Surgery: the Effects of Early Initiated and Supervised Mobilization
The aim is to investigate the effect of early initiated and supervised mobilization continued after discharge as management of postoperative pain and recovery following obesity surgery, including patient experiences, pain coping…
- Conditions
- Postoperative Pain, Acute, Postoperative Pain, Chronic, Bariatric Surgery, Mobilization
- Trial name
- NCT06222151
- Testing
- Intervention 1: Mobilization during hospitalization, Intervention 2: Mobilization the first 4 postoperative weeks, Control group
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Obesity, Robot Surgery
Study on the Safety and Efficacy of Domestic Single-Port Robot-Assisted Metabolic Bariatric Surgery.
This study aims to obtain short-term clinical results on the safety and efficacy of single-port robot-assisted metabolic weight loss surgery, and to provide further evidence for the clinical promotion of single-port robot systems.
- Trial name
- NCT07335731
- Testing
- Robot-assisted single-port bariatric surgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China-Japan Friendship Hospital
Obesity, Morbid
Omega Gastric Bypass (150cm) Compared to the Roux-en-Y Gastric Bypass (YOMEGA-2 Multicentric Trial)
Obesity with its consequences such as type 2 diabetes, high blood pressure, dyslipidemia, fatty liver disease, sleep apnea and cancers, remains a major healthcare problem worldwide.
- Trial name
- YOMEGA-2 (NCT06057597)
- Testing
- Laparoscopic OAGB, Laparoscopic RYGB
- Where
- France
- Volunteers
- 368 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gallstone Disease, Ultrasonic Diagnosis
Transabdominal and Laparoscopic Ultrasound in a Bariatric Setting
Every year, many patients undergo weight-loss (bariatric) surgery. While this surgery leads to significant and intended weight loss, it also increases the risk of developing gallstones or other gallbladder problems.
- Conditions
- Gallstone Disease, Ultrasonic Diagnosis, Bariatric Patients Undergoing Bariatric Surgery
- Trial name
- NCT07453186
- Testing
- Diagnostic procedures
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Irbesartan
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03476603
- Testing
- Irbesartan
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Type 2 Diabetes Mellitus (T2DM), Obesity & Overweight
The Transit Bipartition With the Use of a Metallic Anastomosis Clip and Circular Fundocorporeal Gastroplication
This study evaluates a new surgical device - the Metallic Anastomotic Clip (MAC) - for performing a laparoscopic bypass gastroenteroanastomosis with entero-enteric anastomosis (transit bipartition / "dual-path" procedure) in…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity & Overweight, Marginal Ulcer (Peptic) or Erosion, Leakage, Anastomotic
- Trial name
- MACBIPARTFCG (NCT07495020)
- Testing
- Laparoscopic transit bipartition with Metallic Anastomotic Clip and Circular Fundocorporeal Gastroplication, Laparoscopic transit bipartition (gastroenteroanastomosis and entero-enteric anastomosis) use the Metallic Anastomotic Clip and with sleeve gastrectomy, laparoscopic duodenal transit bipartition using the Metallic Anastomotic Clip with circular fundocorporeal gastroplication without gastrectomy
- Where
- Kazakhstan
- Volunteers
- 90 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Surgery, Obesity
A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients
The aim of the study is to demonstrate the superiority of bariatric surgery on the disappearance of NASH without worsening of fibrosis in comparison to medical standard treatment in obese patients (35 kg/m² > BMI ≥ 30 kg/m²) with…
- Conditions
- Surgery, Obesity, NASH - Nonalcoholic Steatohepatitis, Cirrhosis
- Trial name
- NASHSURG (NCT03472157)
- Testing
- Lifestyle therapy, Bariatric surgery
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Lille
Bariatric Surgery
Effects of Respiratory Muscle Training in Post-bariatric Surgery Patients
Obesity is a health condition caused by excessive accumulation of body fat. This condition is linked to the development of chronic diseases and also places increased stress on the respiratory system, leading to respiratory…
- Trial name
- NCT07289958
- Testing
- Institutionalized therapeutic exercise, Inspiratory muscle training, simulated inspiratory muscle
- Where
- Ecuador
- Volunteers
- 52 people
- Sponsor
- University Ramon Llull
Diabetes Type 2, Bariatric Surgery
Magnetic Compression Anastomosis Procedure for Partial Jejuno-ileal Diversion: Evaluating the Feasibility of a Novel Endoscopic Magnetic Metabolic Interventional Therapy
English, Hindi and Gujarati
- Trial name
- 2025/08/EMMIT (NCT07350967)
- Testing
- Magnetic Compression Anastomosis Procedure for Partial Jejuno-ileal Diversion
- Where
- India
- Volunteers
- 5 people
- Sponsor
- iIDEAS Group Holdings Limited
Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and Dyslipemia
Preoperative Optimization With Tirzepatide, Ketogenic Diet, or Standard Care Before One Anastomosis Gastric Bypass Surgery
This study compares three preoperative strategies before one anastomosis gastric bypass(OAGB) for severe obesity. Participants will be assigned to receive either tirzepatide medication for 60 days, a ketogenic diet for 4 weeks…
- Conditions
- Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and Dyslipemia, Obesity (BMI > 35) and High Blood Pressure
- Trial name
- OPTI-OAGB (NCT07622992)
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- Mario Musella MD
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Losartan
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03519893
- Testing
- Losartan
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Bariatric Surgery Candidate
Modulation of the Inflammatory Response in Bariatric Surgery
This study will evaluate how different anesthesia techniques affect inflammation after bariatric surgery. Patients will be randomly assigned to receive one of three approaches: opioid-free anesthesia, intravenous anesthesia with…
- Conditions
- Obesity, Bariatric Surgery Candidate, Inflammation, Postoperative Pain
- Trial name
- MRICBx3 (NCT06915558)
- Testing
- Opioid-Free Anesthesia (OFA), Opioid-Based Intravenous Anesthesia (OBA-IV), Opioid-Based Inhalational Anesthesia (OBA-Inh)
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital HM Nou Delfos
Non-Alcoholic Fatty Liver Disease, Obesity, Morbid
Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
The study is aimed To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obesity, Morbid, Brown Fat, Metabolic Disease
- Trial name
- NCT03875625
- Testing
- Bariatric surgery, Dietitian led life style modification intervention, Conventional care (control)
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Diabete Type 2, Obesity
A Study on the Effect of Bariatric Surgery on Glucose Metabolism in Chinese Obese and Type 2 Diabetes Patients
The study will be conducted in the following population: obese patients with normal glucose tolerance (HbA1c ≤ 5.6%, n=12), pre-sugar patients (5.7% ≤ HbA1c ≤ 6.4%, n=18) and patients with T2DM (HbA1c ≥ 6.4% , n=18).
- Trial name
- NCT05894811
- Testing
- oral glucose tolerance test, MRI
- Volunteers
- 48 people
- Sponsor
- Dongyang Liu
Obesity
Comparison of Acceleromyography and Electromyography in Obese Patients Undergoing General Anesthesia
The goal of this prospective observational study is to compare two different methods of monitoring muscle relaxation during anesthesia - acceleromyography (AMG) and electromyography (EMG) - in people with obesity who are having…
- Trial name
- OBAEG (NCT07283354)
- Testing
- Neuromuscular monitoring with electromyography (EMG), Neuromuscular monitoring with acceleromyography (AMG)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Padova
Morbid Obesity, Bariatric Surgery Candidate
Rivaroxaban Versus Enoxaparin for Prophylaxis of Venous Thromboembolism in Bariatric Surgery
Rivaroxaban versus enoxaparin for prophylaxis of venous thromboembolism in morbidly obese patients undergoing bariatric surgery: An open_label randomized controlled trial
- Trial name
- NCT06689241
- Testing
- Enoxaparin, rivaroxaban
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Bariatric Surgery in Postmenopausal Women
Bone Marrow Fat and Bariatric Surgery-Mediated Bone Loss
Results are inconsistent and further studies are needed to better understand the impact of bariatric surgery on the bone-BMA relationship depending on the type of bariatric surgery: RYGB vs. SG.
- Trial name
- ADIMOS-OB (NCT05005039)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Lille
Obesity, Morbid
Investigating Metabolic, Brain, and Cognitive Alterations Through Bariatric Surgery
Despite global efforts, the prevalence of obesity continues to rise, with rates in Canada tripling over the past three decades. In addition to the well-established risk of cardiometabolic conditions such as heart disease and…
- Trial name
- BRAINS (NCT07704229)
- Testing
- Sleeve Gastrectomy
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Laval University