Clinical trials: Bariatric Surgical Procedure
Heart Failure and Preserved Ejection Fraction, Obesity (Disorder)
OBESE-HFpEF: Towards Preventing Obesity Related HFpEF
Obesity, severe overweight, is a growing problem worldwide and increases the risk of heart failure, especially a type called heart failure with preserved ejection fraction (HFpEF). In HFpEF, the heart becomes stiffer.
- Conditions
- Heart Failure and Preserved Ejection Fraction, Obesity (Disorder), Heart Failure
- Trial name
- OBESE-HFpEF (NCT07539766)
- Where
- Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Pulmonary Atelectasis, Respiratory Tract Diseases
Use of Positive Pressure in Morbidly Obese Patients Undergoing Reduction Stomach Surgery
The aim of this study was to investigate the effects of using positive pressure in the preoperative, intraoperative and postoperative morbidly obese individuals undergoing gastroplasty.
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT01786681
- Testing
- Positive pressure
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Hypoglycemia, Hypoglycemia, Reactive
Post-Prandial Carbohydrate Metabolism in Individuals With and Without Post-Bariatric Surgery Hypoglycemia (PBH)
In this study, the investigators will determine (a) whether metabolism (secretion and turnover) of glucagon is altered in patients with PBH, (b) whether this is affected by a meal, (c) whether PBH affects the ability of the body…
- Conditions
- Hypoglycemia, Hypoglycemia, Reactive, Bariatric Surgery
- Trial name
- NCT07818707
- Testing
- Glucagon for Injection (Fresenius Kabi USA), [6,6-2H2] glucose, [13C9, 15N1]-glucagon
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Obesity
Telemedicine Follow-up for Bariatric Surgery Patients: What Do Patients Prefer
This is a randomized clinical trial that will randomize bariatric patients undergoing laparoscopic sleeve gastrectomy or laparoscopic Roux-en-Y gastric bypass to receive either in-person or telemedicine post-operative follow-up…
- Trial name
- NCT04784286
- Testing
- Telemedicine 30-day post-op visit, In-Person 30-day post-op visit
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obese Adolescents, Bariatric Surgery
Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia
study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia and provide improvement in recovery
- Trial name
- modafinil (NCT07128719)
- Testing
- Modafinil
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Morbid Obesity
Efficacy and Mechanism Study of Bariatric Surgery to Treat Moderate to Severe Obesity in Han Chinese Population
This is a long-term follow-up and interventional study in individuals who have been diagnosed with moderate to severe obesity with or without diabetes.
- Trial name
- NCT02653430
- Testing
- Sleeve gastrectomy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Eye Diseases, Obesity Associated Disorder
Ophthalmologic Evaluation of Patients With Obesity and Metabolic Syndrome Before and After Bariatric Surgery
The aim of this study was to investigate the pathogenic role of obesity on blinding eye diseases in a population of severely obese patients with no history of eye diseases, and to verify whether weight loss induced by bariatric…
- Trial name
- NCT04926714
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- XiaoYong Liu
Obesity
Changes in Sexual Function Following Bariatric Surgery
The main purposes of the study are to compare changes in sexual function, changes in sex hormones, and changes in body image and marital satisfaction at 12, 24, 36 and 48 months postoperatively in two groups: individuals who…
- Trial name
- NCT00670098
- Testing
- Bariatric surgery, lifestyle intervention (behavioral weight loss)
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity, Morbid
Suboptimal Weight Loss After Gastric Bypass Surgery
Bariatric surgery is the only long-term established treatment for morbid obesity. However, some patients experience suboptimal weight loss after surgery and/or experience a significant weight regain.
- Trial name
- NCT01829906
- Testing
- Multidisciplinary outpatient programme, Inpatient lifestyle programme
- Where
- Norway
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Pain, Postoperative, Morbid Obesity
Clinical Proposal for the Comparison of Intraperitoneal Anesthetic to Injected Local Anesthetic
The purpose of this study is to determine if pre-incisional lidocaine injection, instilled liquid bupivacaine, intra-abdominal aerosolized bupivacaine, or post-operative bupivacaine injection is superior in post-operative pain…
- Trial name
- NCT00508976
- Testing
- Injected bupivacaine post-operatively, Streamed bupivacaine versus streamed normal saline, Aerosolized bupivacaine versus aerosolized saline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pinnacle Health System
Obesity
Machine Learning for Reclassification of Obesity
The goal of this study is to employ or develop computational modeling techniques for the precise reclassification of obesity into subgroups.
- Trial name
- NCT04282837
- Testing
- AI classification of patients with obesity
- Where
- China
- Volunteers
- 2,495 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Obesity, Type 2 Diabetes Mellitus
Changes in Insulin Sensitivity After Weight Loss
This study is designed to compare the changes in insulin sensitivity as well as gastrointestinal hormone levels in diabetic and non-diabetic obese individuals who are undergoing weight loss procedures.
- Conditions
- Obesity, Type 2 Diabetes Mellitus, Insulin Resistance
- Trial name
- NCT00627484
- Testing
- Gastric bypass, Gastric banding, Sleeve gastrectomy
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity, Bariatric Surgery Candidate
Gastrointestinal Physiological Conditions in Obesity and After Bariatric Surgery
Over the years, obesity has become a major public health concern. The increasing rates of obesity are associated with an enhanced demand for weight-loss with bariatric surgery as a treatment option.
- Trial name
- GASTON (NCT03783052)
- Testing
- SmartPill in fasted state, SmartPill in fed state, Aspiration
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity and Obesity-related Medical Conditions, Sarcopenic Obesity
Changes in Fat and Muscle Tissue Function and Their Impact on Metabolic Health After Bariatric Surgery
This prospective, single-center observational cohort study aims to explore the relationship between skeletal muscle quality, fat distribution, and metabolic health in Chinese patients with obesity, and to evaluate how bariatric…
- Conditions
- Obesity and Obesity-related Medical Conditions, Sarcopenic Obesity, Adipose Tissue, Abdominal
- Trial name
- NCT07035483
- Testing
- bariatric surgery
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shaihong Zhu
Liver Function, Bariatric Surgery
the Related Factors of Bariatric Surgery on Liver Function
Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including…
- Trial name
- NCT03689790
- Testing
- sleeve gastrectomy, gastric bypass
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Jinan University
Morbid Obesity, Type2 Diabetes
Elucidating the Mechanism of Remission of Type 2 Diabetes in Morbid Obese Patients After Bariatric Surgery
The main aim of this study is to elucidate the mechanism of the remission of type 2 diabetes in the morbid obese patients after laparoscopic sleeve gastrectomy.
- Trial name
- NCT03038373
- Testing
- Laparoscopic Sleeve Gastrectomy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dasman Diabetes Institute
Obesity & Overweight, Collagen Protein
Collagen Supplements and Post-MBS Muscle Mass/Body Image
This prospective, observational cohort study aims to evaluate whether the use of collagen-containing supplements is associated with differences in muscle mass, body composition, and body image among patients who have undergone…
- Conditions
- Obesity & Overweight, Collagen Protein, Bariatric Surgery, Metabolic and Bariatric Surgery
- Trial name
- NCT07809152
- Testing
- Collagen-containing supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mudanya University
Atelectasis, Postoperative Pulmonary
Optimizing PEEP in Laparoscopic Bariatric Surgery Using Bedside Lung Ultrasound
Lung ultrasound imaging is a promising non-invasive, non-radiant, portable and easy to use tool that as yet to be studied in the intraoperative setting.
- Trial name
- NCT04269564
- Testing
- stepwise PEEP
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bariatric Surgery Candidate, Severe Obesity
Single Anastomosis Duodenal Ileal Bypass (SADI) for Sleeve Revision
The goal of this study is two part: 1) to add to the literature which is still somewhat sparse with numbers of patients undergoing the Single Anastomosis Duodenal Ileal Bypass (SADI) as a revision for laparoscopic sleeve…
- Trial name
- SADI (NCT04165694)
- Testing
- Single Anastomosis Duodenal Ileal Bypass (SADI)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Weight Loss, Bariatric Surgery
Outcomes After Weight Loss Surgery in Low-Risk Patients
The purpose of this research is to determine patient-reported outcomes after weight loss surgery, including changes in health, mood, quality of life, health satisfaction, and emotional health, in low-risk patients.
- Trial name
- NCT05699083
- Testing
- Body Image/Self-Esteem Questionnaires
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. Feiz & Associates