Clinical trials: Basal Cell Carcinomas
Lung Cancer Metastatic, Renal Cell Carcinoma
Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO
Immunotherapy (IO), such as treatment with anti-PD-1, PD-L1, or CTLA-4 inhibitors, is a rapidly expanding treatment for multiple metastatic cancers with improved survival for certain cancers.
- Conditions
- Lung Cancer Metastatic, Renal Cell Carcinoma, Head and Neck Cancer, Triple Negative Breast Cancer
- Trial name
- MOIO (NCT05078047)
- Testing
- Reduced dose intensity of IO
- Where
- 33 sites in France
- Volunteers
- 646 people
- Sponsor
- UNICANCER
Basal Cell Carcinoma
Treatment of Nodular Basal Cell Carcinoma (BCC) With Imiquimod 5% Cream After Curettage
To assess the efficacy of treating a nodular basal cell carcinoma with imiquimod cream after initial treatment with curettage
- Trial name
- NCT00314756
- Testing
- imiquimod
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Cell Carcinoma
Tirbanubulin (Klisiry®) in the Treatment of Basal Cell Carcinoma
his is a Phase 2, Single-Arm, Open-Label, Single Center, to Assess Efficacy and Safety of Tirbanibulin Ointment 1% in Adult Subjects with superficial basal cell carcinoma (sBCC) not arising on the face or scalp
- Trial name
- Tirbaso (NCT06112522)
- Testing
- Tirbanibulin
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Basal Cell Carcinomas
Vismodegib in Basal Cell Carcinomas (BCC) Chemoprevention
This study is a single site double blinded Phase II study to evaluate the chemopreventative effectiveness of vismodegib in the treatment of subjects at high risk for developing basal cell carcinomas (BCC).
- Trial name
- NCT02067104
- Testing
- Vismodegib
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Arizona
Basal Cell Carcinoma
AI-Based Risk Classification and Histopathological Subtype Prediction of Basal Cell Carcinoma Using Dermoscopic Images
This retrospective observational study aims to develop and evaluate a convolutional neural network (CNN)-based artificial intelligence model for risk classification and histopathological subtype prediction of basal cell carcinoma…
- Trial name
- BCC-AI (NCT07677124)
- Where
- Turkey (Türkiye)
- Volunteers
- 2,500 people
- Sponsor
- Istanbul Training and Research Hospital
Non-Melanoma Skin Cancer (NMSC), Basal Cell Carcinoma of Skin
The Role of Radiotherapy for the Management of Non-melanoma Skin Cancer in Denmark.
The goal of this observational study is to learn about the long-term effects of radiotherapy for people who were treated for non-melanoma skin cancer (NMSC) in the head and neck area.
- Conditions
- Non-Melanoma Skin Cancer (NMSC), Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma of the Skin
- Trial name
- DOSCA-2 (NCT07347392)
- Testing
- Follow-up visit at least two years after treatment
- Where
- Denmark
- Volunteers
- 2,900 people
- Sponsor
- University of Aarhus
Carcinoma, Basal Cell
PD-1 in Patients With Advanced Basal Cell Carcinoma Who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or Were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy
The primary objective is to estimate the objective response rate (ORR) for metastatic Basal Cell Carcinoma (BCC) (group 1) and for unresectable locally advanced BCC (group 2) when treated with cemiplimab as a monotherapy
- Trial name
- NCT03132636
- Testing
- cemiplimab
- Where
- 71 sites in United States, Austria and 8 more
- Volunteers
- 138 people
- Sponsor
- Regeneron Pharmaceuticals
Basal Cell Carcinoma, Squamous Cell Carcinoma of the Skin
CivaDerm(TM) Surface Therapy Pilot Study
This is a pilot study to determine the usefulness of new brachytherapy device that utilizes active components (palladium-103) of standard devices in a novel configuration, which may benefit basal cell and squamous cell carcinoma…
- Trial name
- NCT04480645
- Testing
- CivaDerm
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CivaTech Oncology
Bladder Cancer, Breast Cancer
Chemotherapy in Treating Patients With Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I/II trial to study the effectiveness of oblimersen in treating patients who have solid tumors…
- Conditions
- Bladder Cancer, Breast Cancer, Colorectal Cancer, Esophageal Cancer
- Trial name
- NCT00003103
- Testing
- oblimersen sodium, docetaxel
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Basal Cell Carcinoma
Video-Based Treatment Options for Basal Cell Carcinoma
The purpose of this study is to determine if presenting treatment options to basal cell carcinoma patients in video format will improve efficiency and allow patients to receive consistent, comprehensive, visually-depicted…
- Trial name
- NCT02158650
- Testing
- Video-Based Informed Consent
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Emory University
Carcinoma, Basal Cell, Carcinoma, Squamous Cell
Analysis of Melanocytes (Pigment Cells) in Sun-Exposed Skin
The purpose of this study is to estimate and define the mean number, degree of confluence, and depth of penetration of melanocytes in chronically sun exposed skin of the head and neck using Mart-1 immunostains on frozen sections.
- Trial name
- NCT00875381
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Melanoma (Skin), Non-melanomatous Skin Cancer
Bioelectric Field Imaging in Diagnosing Melanoma and Other Skin Cancers in Patients With Skin Lesions
RATIONALE: New diagnostic procedures, such as bioelectric field imaging, may help find and diagnose melanoma and other skin cancers. It may also be a less invasive way to check for skin cancer.
- Trial name
- NCT00391300
- Testing
- bioelectric field imaging, biopsy, histopathologic examination
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Eastern Virginia Medical School
Breast Cancer, Head and Neck Cancer
Docetaxel in Treating Patients With Solid Tumors and Abnormal Liver Function
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of docetaxel in treating patients with advanced solid…
- Conditions
- Breast Cancer, Head and Neck Cancer, Lung Cancer, Ovarian Cancer
- Trial name
- NCT00002901
- Testing
- docetaxel
- Where
- 3 sites in United States
- Sponsor
- City of Hope Medical Center
Basal Cell Carcinoma, BCC
The Efficacy and Safety of Using Intralesional 5-fluorouracil for Basal Cell Carcinoma
The investigators want to assess the safety and efficacy of using intralesional 5-FU for the management of different types of BCC (including all the types EXCEPT the infiltrative one), by estimating different outcomes after the…
- Trial name
- NCT06150144
- Testing
- 5-Fluorouracil, SURGERY
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- University of Aleppo
Basal Cell Carcinoma
Clinical Trial to Evaluate BO-112 in Patients With Basal Cell Carcinoma (BCC)
This is a multicenter, phase 2b, open-label, non-randomized, clinical trial to evaluate safety, tolerability, pharmacodynamics and preliminary efficacy of intra-lesional BO-112 in patients with resectable primary low and high…
- Trial name
- SPOTLIGHT204 (NCT06422936)
- Testing
- BO-112
- Where
- 10 sites in Israel, Spain
- Volunteers
- 50 people
- Sponsor
- Highlight Therapeutics
Non-Melanoma Skin Cancers
A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratoses and Non-Melanoma Skin Cancers
Open-Label study evaluating safety and efficacy of SM-020 Gel 1.0% in subjects with Seborrheic Keratoses and Non-Melanoma Skin Cancers (i.e. Basal Cell Carcinoma and Squamous Cell Carcinoma In Situ).
- Trial name
- NCT06409195
- Testing
- SM-020 1% Gel
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- DermBiont, Inc.
Adult Solid Tumor, Breast Cancer
Docetaxel and St. John's Wort in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. St. John's wort may interfere with the effectiveness of chemotherapy.
- Conditions
- Adult Solid Tumor, Breast Cancer, Head and Neck Cancer, Kidney and Urinary Cancer
- Trial name
- NCT00041171
- Testing
- Hypericum perforatum, docetaxel
- Sponsor
- Alliance for Clinical Trials in Oncology
Melanoma, Cutaneous Squamous Cell Carcinoma
Personalised Immunotherapy Platform
This is a non-interventional study to prospectively test a suite of predictive biomarker models of immunotherapy resistance in patients with melanoma, non-melanoma skin cancers and other solid tumours.
- Conditions
- Melanoma, Cutaneous Squamous Cell Carcinoma, Basal Cell Carcinoma, Merkel Cell Carcinoma
- Trial name
- PIP-PREDICT (NCT06536257)
- Testing
- Predictive model
- Where
- 3 sites in Australia
- Volunteers
- 1,000 people
- Sponsor
- Melanoma Institute Australia
Basal Cell Carcinoma
STEVIE: A Study of Vismodegib in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma
This single-arm, open-label, multi-center study will evaluate the safety and efficacy of vismodegib (GDC-0449) in patients with locally advanced or metastatic basal cell carcinoma.
- Trial name
- NCT01367665
- Testing
- vismodegib
- Where
- 181 sites in Argentina, Australia and 35 more
- Volunteers
- 1,232 people
- Sponsor
- Hoffmann-La Roche
Basal Cell Carcinoma
Checking Wether the m-ALA Cream Could Mark Correctly the Borders of BCC's Tumors
Correlation between Mohs surgery and microscopic fluorescence photometry in determination of histological borders in Basal Cell Carcinoma .
- Trial name
- NCT00449358
- Testing
- apply methyl-ALA cream
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Assuta Hospital Systems