Clinical trials: Baseline
Caffeine, Placebo
Placebo Effects Investigated by Different Experimental Designs
This study aims to investigate the neurophysiological mechanisms of placebo perceived as caffeine during a motor task. Central and peripheral measures (i.e. electroencephalography and electromyography) will be assessed.
- Conditions
- Caffeine, Placebo, Baseline
- Trial name
- NCT04317157
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Spine Disease, Characteristics Disease
Baseline-characteristics of Patients Referred to a Secondary Spine Centre
A retrospective cohort study will be conducted in Zuyderland Medical Centre Heerlen, the Netherlands. All patients that were referred to the spine-centre between 01.01.2019 and 31.12.2019 will be included for analysis.
- Conditions
- Spine Disease, Characteristics Disease, Spinal Disease, Demography
- Trial name
- CHAPARS (NCT04877470)
- Testing
- Consultation at spine-centre
- Where
- Netherlands
- Volunteers
- 4,855 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Disaster, PTSD
Feasibility and Efficacy of a Digital Mental Health Intervention for Teen Wildfire Survivors
In October, 2017, Northern California experienced devastating and historic wildfires. Sonoma Rises is an app designed for anyone who was impacted by this event and is intended to help survivors of disaster find their new normal.
- Conditions
- Disaster, PTSD, Adolescent Behavior, Trauma
- Trial name
- NCT03868761
- Testing
- Sonoma Rises
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Stanford University
Decrease in Heart Rate Below Baseline Value
Genetic Determinants of Hemodynamic Response to Esmolol
Beta 1 Adrenergic antagonists (beta blockers) have major role in the treatment of CHF, IHD and hypertension. However, there is large interindividual variability in the response to beta blockers.
- Trial name
- NCT01388036
- Testing
- esmolol
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Healthy
Determination of Baseline Thyroid Status Values in French Adult Population
The objective of this study is to establish reference values in the general population from a Beckman Coulter DxI chemiluminescence assay.
- Trial name
- THYRBECK (NCT03748407)
- Testing
- Dosages of Thyroid parameters
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Hypercholesterolemia
Effect of Niacin in the Lipoprotein (a) Concentration
Objectives. To evaluate the absolute and relative Lp(a) lowering effect of 1g/20 mg and 2 g/40 mg day of Niacin/Laropiprant in subjects with normal Lp(a) (< 30 mg/dL), high Lp(a) (30-60 mg/dL) and very high Lp(a) (> 60 mg/dL).
- Trial name
- NCT01321034
- Testing
- Niacin/Laropiprant
- Where
- 3 sites in Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Asthma-COPD Overlap Syndrome
This Study Include Asthma Chronic Obstructive Pulmonary Disease (COPD) Overlap Patients.Patients Were Vitamin D Deficient.Age Range 40-70 Years, Smokers.Patients Were Advised to Take Either Placebo or Vitamin D3.Lung Functions and Exercise Tolerance Were Assessed at Baseline and at 26th Weeks.
Vitamin D3 supplementation doen not change lung functions and exercise tolerance in vitamin D3 deficient ACO patient was the null hypothesis of the research.
- Trial name
- NCT03880734
- Testing
- Cholecalciferol
- Where
- Bangladesh
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Alzheimer Disease, Dementia
Detecting Probable Alzheimer's Disease From Speech Using Linguistical Analysis
The object of this study is to investigate the use of linguistic deficits from speech samples for the early detection of Mild Cognitive Impairment and probable Alzheimer's disease.
- Trial name
- NCT04041895
- Testing
- Audio speech recording
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- East Tennessee State University
Melanoma
SunSmart Intervention in Schools
A prevention study to improve sun exposure behaviors in children after an educational classroom-based intervention.
- Trial name
- NCT03745872
- Testing
- Knowledge Assessment
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hair Loss
For an Investigator-led Hair Study Comparing Between Healthy and Hair Loss Volunteers
This study is to evaluate differences in the gut and follicle/scalp microbiome signature in AGA compared to a non-AGA population.
- Trial name
- NCT07716748
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National Skin Centre
Obesity, Depression
Study of a Holistic Health Program for United Methodist Clergy
This study seeks to test a two-year intervention designed for United Methodist clergy. The intervention consists of: the stress reduction program Williams LifeSkills, adapted for clergy; the 10-session online weight loss program…
- Conditions
- Obesity, Depression, Diabetes, Hypertension
- Trial name
- SpiritedLife (NCT01564719)
- Testing
- Holistic health
- Where
- United States
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Duke Clergy Health Initiative
Urethritis, Healthy Men Age 18-50 With no Urethral Symptoms
Establishing Baseline Sysmex UF-5000 Flow Cytometer Results in Healthy Men
Acute urethritis (inflammation of the male urethra) affects millions of men in the United States each year. Effective management of STIs is complicated by asymptomatic infections, as men often delay seeking care until symptoms…
- Trial name
- NCT06951009
- Testing
- Colli-Pee, standard of care 60 mL urine cup, Urinalysis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Indiana University
Influenza
Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the 2010/2011 Season
Influenza (flu) viruses change continuously, therefore also the parts of viruses used in influenza vaccines can vary from year to year.
- Trial name
- NCT01146015
- Testing
- Trivalent influenza subunit vaccine Influvac
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Abbott Biologicals
Aging
PUER ("Previously Unrecognized Emerging Risks") Life Clinical Study
This is a minimal risk, prospective, non-randomized, multi-center population based observational study to establish a physical baseline profile for individual study subjects using various modalities (blood draws, non-invasive…
- Trial name
- PUER (NCT05687578)
- Testing
- Measurements Only
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Puer Research, LLC
Vagina Disease, Vaginal Community State Type
Baseline Study of Vaginal Microbiota in Healthy Chinses Female Population
The reproductive tract microecology is an important part of the human microbial system. Microorganisms and the host reproductive tract environment form a stable symbiotic relationship.
- Trial name
- BSOVM (NCT04887636)
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Yellow Fever (Healthy Volunteers), Biopsy/Methods
Baseline Assessment of Skin Resident Memory T Cells in Healthy Unvaccinated Participants
In The main GeKoSkimm trial (= A randomized controlled trial to compare the immunogenicity and skin imprinting of intradermal, subcutaneous and intramuscular yellow fever vaccination) the investigators try to understand whether…
- Trial name
- NCT07636551
- Testing
- Skin punch biopsy, Blood samples
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Panhypopituitarism
Baseline Sexual Function, Cognitive Function, Body Composition and Muscle Parameters and Pharmacokinetics of Transdermal Testosterone Gel in Women With Hypopituitarism
The purpose of this study is to determine the blood levels of testosterone gel administered for a week to women with hypopituitarism and determine if this leads to testosterone replacement in a normal range for women.
- Trial name
- NCT00144404
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Concussion, Brain, Dynamic Vision Tests
A Comparison of Dynamic Vision Between College Athletes & Controls
The purpose of this study is to establish baseline reference values for tests of static and dynamic visual acuity and gaze stabilization in collegiate athletes and non-athletes, and to determine if there are differences in vision…
- Trial name
- NCT05819489
- Testing
- Dynamic Vision Testing
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- California State University, Northridge
Uveitis, Posterior
Corneal Endothelial Cell Density in Eyes Treated With a Fluocinolone Acetonide Intravitreal Implant
An Observational Change-From-Baseline Evaluation of Corneal Endothelial Cell Density in Eyes Treated with a Fluocinolone Acetonide Intravitreal Implant
- Trial name
- NCT03145025
- Testing
- Retisert, Fluocinolone Acetonide Intravitreal Implant
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Chronic Constipation, Constipation
Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating
The purpose of this study is to evaluate the efficacy and safety of linaclotide compared with placebo in patients with chronic constipation (CC) and prominent abdominal bloating.
- Trial name
- NCT01642914
- Testing
- Linaclotide 290 micrograms, Linaclotide 145 micrograms
- Where
- 151 sites in United States, Canada
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Forest Laboratories