Clinical trials: Basic Physiology
Stroke, Rehabilitation
Rhythmic-Based Training with Immersive Mirror Visual Feedback for Neuro-Rehabilitation
In the proposed study, the investigators assumed that rhythmic-based training with immersive mirror visual feedback will provide a better treatment effects than traditional mirror therapy for the patients with unilateral stroke.
- Conditions
- Stroke, Rehabilitation, Virtual Reality, Mirror Movement Therapy
- Trial name
- NCT06056219
- Testing
- Mirror therapy, Virtual reality-based mirror therapy with rhythmic skill training, Task-oriented training
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Aging, Mobility Limitation
Physical Activity to Improve Physical Function in a Community-Based Health Ministry
This study is being conducted to test if a program with physical activity and learning about movement (including goal setting, benefits of physical activity, and how to increase physical activity gradually) helps people to become…
- Trial name
- NCT04203030
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Osteoarthritis
Study of Effectiveness of Hand Exercises to Treat Symptoms of Hand Osteoarthritis
Participants in this study will do hand exercises once per day for 16 weeks. The purpose of the study is to determine if hand exercises designed to improve range of movement and strength are an effective way to decrease…
- Trial name
- NCT00375947
- Testing
- Hand Exercise
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The Arthritis Research Institute of America
Healthy
Use of Real-Time Functional Magnetic Resonance Imaging Neurofeedback to Improve Motor Function in Cerebellar Ataxia
This project will study the feasibility of motor rehabilitation in people with cerebellar ataxia using real-time functional magnetic resonance imaging neurofeedback (rt-fMRI NF) in conjunction with motor imagery.
- Trial name
- fMRI (NCT05436249)
- Testing
- Neurofeedback treatment, At-home therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Emotional/Behavioral Function, Academic Performance
Efficacy of a Brief Intervention for School Clinicians (BRISC)
Research shows that the majority of all mental health (MH) treatment for children is delivered in schools. Unfortunately, however, school mental health (SMH) providers rarely use evidence-based approaches and are often poorly…
- Trial name
- BRISC (NCT03939208)
- Testing
- BRISC, SAU
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sexual Behavior, Climactericum
The Effect of Sexual Counseling Based on the BETTER Model on Sexual Function and Quality of Sexual Life in Postmenopausal Women
Sexual life, an integral part of overall health, remains one of the most neglected, undervalued, and problematic areas within today's healthcare system Various management strategies exist for managing sexual dysfunction…
- Conditions
- Sexual Behavior, Climactericum, Sexuality Education
- Trial name
- NCT07261943
- Testing
- The group that received sexual education based on the BETTER model
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Disability Physical
Community-based Complex Intervention to Prevent Loss of Physical Function and Disability in Home-dwelling Older Adults
The aim of this study is to compare the effect of 12 weeks group-based exercise program enhanced with 24 weeks health empowerment program (HEP) to an extended usual care condition (the HEP program alone) on physical function…
- Trial name
- NCT04531852
- Testing
- CALSTI - Complex Active Lifestyle Intervention, SEMAI - Self-Management Intervention
- Where
- 3 sites in Denmark
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Post-cardiac Surgery
Group-based Cardiac Rehabilitation on Patients With Coronary Artery Bypass Graft Surgery
1. To determine the effect of Moderate intensity continuous training on Pulmonary function of CABG patients. 2. To determine the effect of MICT on aerobic Capacity of CABG patients.
- Trial name
- NCT06317376
- Testing
- MICT with Aerobic exercise on treadmill, standard hospital protocol
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)
Background: Irritability is an elevated proneness to anger. Children with irritability have difficulty tolerating frustration. They get angry and have temper outbursts more easily than their others their age.
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Normal Physiology
- Trial name
- NCT05357495
- Testing
- Affective Posner fMRI frustration induction task
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Basic Physiology, Brain Stimulation
Transcranial Direct Current Stimulation (tDCS) in the Primary Motor Cortex in Healthy Individuals
The main aim of this study is to assess the short-term effects of active-tDCS (a-tDCS) on the M1 regarding sensorimotor variables such as discriminative sensation, pressure pain threshold and electromyographic activity compared…
- Trial name
- NCT04148547
- Testing
- Sooma transcranial direct current stimulation device
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Physical Activity
Supervised Group-based Walking Intervention Among Inactive Older Adults in Saudi Arabia
The purpose of the proposed study is to compare the effects of supervised group-based walking and non-supervised individual-based walking interventions on frailty, cognitive function and quality of life among inactive older…
- Trial name
- NCT05151575
- Testing
- supervised group-based walking and non-supervised individual-based walking interventions
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Child Behavior
Physical Activity Intervention Effects on Executive Function, Physical Activity and Sedentary Behaviour in Children
The current study aims to implement the Activity Breaks intervention and evaluate its effectiveness on outcome measures of executive function (EF), physical activity (PA), and sedentary behaviour (SB) in school children.
- Trial name
- NCT06376864
- Testing
- Activity Breaks
- Where
- Hong Kong
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Traumatic Brain Injury
PC-Based Cognitive Rehabilitation for Traumatic Brain Injury (TBI)
The investigators evaluated whether it was possible to improve the measurement of memory, attention, and executive function in patients who have suffered traumatic brain injury through the use of computer-based testing.
- Trial name
- NCT00927576
- Testing
- Digit span testing, Spatial span testing, Finger tapping
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hyperkyphosis
Postural Management of Hyperkyphosis in Cardiac Rehab Patients
The goal of this clinical trial is to evaluate the efficacy of a home-based exercise program in managing hyperkyphosis, and its impact on physical performance and pulmonary function among cardiac rehabilitation patients.
- Trial name
- NCT06563882
- Testing
- Home-based exercise program, No intervention
- Where
- Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Ketosis, Ketonemia
Effects of Exogenous Ketosis on Renal Function, Renal Perfusion, and Sodium Excretory Capacity in Healthy Subjects
This is a randomized, placebo-controlled, double-blinded crossover design. Fifteen healthy subjects will be randomized to receive either ketone bodies (KE4) or placebo delivered by KetoneAid.
- Trial name
- KETO (NCT05980858)
- Testing
- Beta-hydroxybutyrate
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gødstrup Hospital
Eccentric Exercise, Home-based Training
Effects of Eccentric Training at Long Muscle Length on Functional Capacities of Elderly Adults
As aging leads to a decline in muscle function and overall physical performance, interventions targeting muscle strength and neuromechanical properties are critical for maintaining functional independence in older adults.
- Conditions
- Eccentric Exercise, Home-based Training, Elderly Adults
- Trial name
- EMULE (NCT06953258)
- Testing
- Home-based eccentric training at long muscle length, Conventional home-based training
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Robin Souron
Aging
Mind-body Interventions for Healthy Aging
The goal of this study is to examine the impact of mind-body interventions in enhancing behavioral and neural correlates of attentional control in older adults.
- Trial name
- HealthyAgers (NCT03626532)
- Testing
- Mindfulness-Based Stress Reduction (MBSR), Lifestyle Education (LifeEd)
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Exercise, Ultra-endurance Running
Effect of Exogenous Ketosis During Ultra-endurance Exercise
The aim of this study is to investigate the effect of oral ketone administration during and immediately after an ultramarathon. Potential changes in cognitive function (reaction time, number of errors), running performance, jump…
- Conditions
- Exercise, Ultra-endurance Running, Ketosis, Skeletal Muscle
- Trial name
- NCT05407753
- Testing
- Ketone ester
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Executive Function
Brain Games to Improve Executive Function in São Paulo, Brazil
A growing body of research has highlighted the critical importance of children's self-regulation and executive function skills for their school performance as well as for their later life outcomes.
- Trial name
- NCT03491488
- Testing
- Brain Games
- Where
- Brazil
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Valvular Heart Disease
Effect of Desflurane on Cardiac Function During Cardiac Surgery: Tissue Doppler Imaging of Mitral Valve Annular Velocity
The purpose of this study is to determine desflurane's dose-dependent effect on left ventricular (LV) function in cardiac surgery.
- Trial name
- NCT02003885
- Testing
- increment of desflurane
- Where
- South Korea
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center