Clinical trials: Basic Physiology
Duchenne Muscular Dystrophy
Telerehabilitation-based Motor Imagery Training in Children With Duchenne Muscular Dystrophy
When the field of neurorehabilitation is examined, most of the current physiotherapy and rehabilitation approaches are based on real movements to stimulate damaged motor neural connections through neuroplasticity.
- Trial name
- NCT06109103
- Testing
- telerehabilitation-based motor imagery training, telerehabilitation-based physiotheraphy training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healhty
Effect of Chronotype on Balance and Cognitive Function
Balance is the ability of an individual to maintain posture against gravity and sustain stability during movement; it depends on the coordinated functioning of the proprioceptive, visual, and vestibular systems, as well as the…
- Trial name
- NCT07691866
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Gedik University
Healthy Ageing, Cognitive Decline
Fitness, Ageing, and Bilingualism (FAB): The Benefits of Regular Exercise and Bilingualism for Language Abilities in Healthy Ageing.
This project investigates the relative benefits of regular physical activity and bilingualism for ameliorating cognitive decline in healthy ageing, with a particular focus on language function.
- Conditions
- Healthy Ageing, Cognitive Decline, Cardiorespiratory Fitness
- Trial name
- FAB (NCT07443189)
- Testing
- Home-Based HIIT
- Where
- 2 sites in Norway, United Kingdom
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of Agder
Musculoskeletal Health, Adolescent Growth and Development
Design and Validation of a Personalized Preventive System for Adolescents Based on Biological Maturity, Body Composition, and Musculoskeletal Function.
This study aims to evaluate the effectiveness of a personalized preventive physiotherapy and exercise program based on biological maturation status in adolescents aged 14 to 15 years.
- Conditions
- Musculoskeletal Health, Adolescent Growth and Development, Injury Prevention
- Trial name
- PREVEN-KID (NCT07385794)
- Testing
- Personalized Preventive Physiotherapy and Exercise Program
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Aging
Effects of Home-Based Ankle Training Program on The Muscle Strength, Balance and Gait Function in the Elderly
The occurrence of frequent falls influences the independence of the elderly's physical functions, and the factors related to falls include: weakness in the lower limbs, age, past injury experiences and so forth.
- Trial name
- NCT05790369
- Testing
- Resistance training (New ankle machine training), Resistance training (Elastic band training )
- Where
- Taiwan
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Cognition, Neurovascular Coupling Mechanism and Cognitive Function
The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults
The goal of this pilot clinical trial is to test whether transcranial photobiomodulation (tPBM), a non-invasive brain stimulation technique using near-infrared light, can improve brain blood flow regulation (neurovascular…
- Conditions
- Cognition, Neurovascular Coupling Mechanism and Cognitive Function, Neurovascular Control, Brain Aging
- Trial name
- NCT07209683
- Testing
- transcranial photobiomodulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Diabetes Mellitus, Cognitive Impairment
Relationship Between Diabetes and Cognitive Impairment Based on Olfactory Function Assessment and Functional MRI
The purpose of this study is to explore the relationship between diabetes and cognitive impairment by olfactory function assessment and functional MRI.
- Conditions
- Diabetes Mellitus, Cognitive Impairment, Obesity
- Trial name
- NCT02738671
- Testing
- Cognitive assessment, functional magnetic resonance imaging, olfactory function measurement
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Parkinson Disease
Changes in Metabolic Activity, and Gait Function by Dual-task Cognitive Game-based Treadmill Intervention in Parkinson's Disease.
The present proposal will evaluate the neural underpinnings of (a) the decline of mobility function in Parkinson's disease (PD), and (b) the effects of an innovative computer-guided dual-task (DT) mobility training platform…
- Trial name
- CMAGDT (NCT04415775)
- Testing
- Game based treadmill Program, Conventional Gait Rehabilitation
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Physiologic Changes, Exercise
Chrysin Exercise Performance Pilot Study
This single-arm pilot study evaluates within-subject changes in aerobic capacity, heart rate responses, cycling power output, and related physiological measures in healthy adults during and after 30 days of supplementation with a…
- Conditions
- Physiologic Changes, Exercise, Physiological Changes (Heart Rate)
- Trial name
- NCT07872111
- Testing
- Chrysin LipoMicel
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Isura
Age:18-70 Years, Acute Severe Disease
Metabolomics Dynamics Study for Severe Patient
Acute severe disease is a major public health challenge that often affects young adults.In past decade, there are lot of new techniques have been developed that aim to improve the outcome of acute severe disease, But few of these…
- Conditions
- Age:18-70 Years, Acute Severe Disease, Acute Physiology And Chronic Health Evaluation(APACHE)II>10
- Trial name
- NCT02164786
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sichuan Academy of Medical Sciences
Healthy Volunteers, Child Development
Play-Based Motor Training in Children Aged 7-10 Years
This randomized controlled study evaluated the effects of an 8-week structured play-based motor training program on motor competence in children (boys and girls) aged 7-10 years.
- Trial name
- PBMT-DC (NCT07771959)
- Testing
- Structured Play-Based Motor Training Program, Usual Physical Education
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
TBI (Traumatic Brain Injury), Brain Concussion
Dual-Task Exercise for Mild Traumatic Brain Injury (mTBI)
The investigators previously developed a virtual 14-day dual-task walking exercise program and tested its feasibility with individuals with mild traumatic brain injury (mTBI) history.
- Conditions
- TBI (Traumatic Brain Injury), Brain Concussion, Clinical Trial, Rehabilitation
- Trial name
- NCT06037603
- Testing
- Brain & Walk Exercise Every Day (BraW-Day)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Brain Fog, Cognitive Impairment
Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain Fog
This randomized controlled trial aims to investigate the effects of cognitive task-based walking exercise on cognitive function, depressive symptoms, sleep quality, and quality of life in older adults experiencing brain fog.
- Conditions
- Brain Fog, Cognitive Impairment, Geriatric Population
- Trial name
- NCT07396779
- Testing
- Cognitive Task-Based Walking Exercise, Walking-Only Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medipol University
Hypertension
High-Intensity Interval Versus Moderate-Intensity Continuous Water Based Exercise in Hypertensive Older Individuals
This study will investigate the acute and chronic effects in hemodynamic and autonomic variables to high-intensity interval versus moderate-intensity continuous heated water-based exercise in older individuals with hypertension.
- Trial name
- HExOLD (NCT04126785)
- Testing
- High Intensity Interval Exercise in Heated Water-Based, Continuous Moderate Exercise in Heated Water-Based, Control Group
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Older People
Explore the Effects of Virtual Reality Natural Environment of Older People
The objective of this study is to evaluate the effectiveness of virtual natural environment interventions on attention and mood among community-dwelling older adults in Taiwan.
- Trial name
- NCT05803460
- Testing
- Experimental group: Actual nature group, Experimental group: Virtual nature group, Control group: Actual urban group
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Aging, Cognitive Aging
Music Improvisation Training on Cognitive Function in Older Adults
This project will study the effects and mechanisms of a music improvisation training intervention on self-regulation of older adults with and without MCI.
- Conditions
- Aging, Cognitive Aging, Cognitive Impairment, Cognitive Training
- Trial name
- Music Training (NCT06721390)
- Testing
- Piano Improvisation, Music Listening
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stroke, Rehabilitation
Rhythmic-Based Training with Immersive Mirror Visual Feedback for Neuro-Rehabilitation
In the proposed study, the investigators assumed that rhythmic-based training with immersive mirror visual feedback will provide a better treatment effects than traditional mirror therapy for the patients with unilateral stroke.
- Conditions
- Stroke, Rehabilitation, Virtual Reality, Mirror Movement Therapy
- Trial name
- NCT06056219
- Testing
- Mirror therapy, Virtual reality-based mirror therapy with rhythmic skill training, Task-oriented training
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Atrial Fibrillation (AF), Stroke
Population-based Atrial Fibrillation Screening in Individuals With NT-proBNP Above Median in the Tromsø Study
The aim is to investigate whether screening with long-term ECG monitoring in individuals with elevated NT-proBNP leads to a lower incidence of ischeamic stroke and death from vascular causes.
- Conditions
- Atrial Fibrillation (AF), Stroke, NT-pro-BNP, Cognitive Function and Well-Being
- Trial name
- PAFS-Tromsø (NCT07343895)
- Testing
- Long term heart rythm monitoring by ECG247
- Where
- 2 sites in Norway
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Other Endothelial Dystrophy
The Effect of Plant-based Diets (Vegetarian and Vegan) on Endothelial Function and Atherogenic Parameters
The investigators' hypothesis is that a plant-based diet may be beneficial if nutritional deficiencies will be corrected. The aims of the present proposal are to 1) study endothelial functions of subjects on well-defined…
- Trial name
- NCT02153138
- Testing
- Endo-pat 2000, carotid intima media thickness Ultrasound, Dexa- Bone densitometer & Bone ultrasonometer System
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pediatric Obesity, Executive Function
Acceptance-based Care for Child Eating and Physical Activity Treatment
The purpose of this study is to develop and pilot test a new type of patient-centered, family-based treatment for children aged 8-12 with obesity and their caregivers.
- Conditions
- Pediatric Obesity, Executive Function, Self-Regulation
- Trial name
- ACCEPT (NCT03368716)
- Testing
- Acceptance-based Behavioral Treatment (ABBT)
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham