Clinical trials: Basic Physiology, open to volunteers
Primary Insomnia
Acupoint Selection Based on Meridian Theory in Primary Insomnia of Liver Depression and Spleen Deficiency Type
The classical literature combined with modern medicine to select acupoints, in order to intervene in the autonomic nerve function of the superior cervical sympathetic ganglion as an opportunity, put forward the meridian acupoints…
- Trial name
- NCT06782815
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Chuanlong Zhou
Multiple Sclerosis
Home-Based Exergame Rehabilitation for Upper Limb Function in People With Multiple Sclerosis
This randomized pilot clinical trial aims to evaluate the effectiveness, feasibility, and cost-effectiveness of a semi-autonomous upper-limb rehabilitation program based on therapeutic exergames in people with Multiple Sclerosis…
- Trial name
- NCT07430462
- Testing
- Exergame-Based Upper Limb Rehabilitation Program, Conventional Home-Based Physiotherapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Marina Castel Sánchez
Lymphedema, Gait Dysfunction
Impact of Virtual Reality (VR) Based Exercises on Lower Limb Lymphedema Outcomes (LELO)
This randomized controlled study aims to investigate the effects of virtual reality (VR)-assisted gait training, in addition to Complex Decongestive Therapy (CDT), on gait parameters, physical function, quality of life, and edema…
- Conditions
- Lymphedema, Gait Dysfunction, Physical Rehabilitation, Chronic Edema
- Trial name
- VR-LELO (NCT07472543)
- Testing
- Complex Decongestive Therapy (CDT) plus virtual reality (VR)-assisted gait training group, Complex Decongestive Therapy alone group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Cardiac Arrest (CA)
Effects of a Web-based Support Programme for Cardiac Arrest Survivors
The overall goal of this clinical trial is to learn if a web-based support programme can improve wellbeing in cardiac arrest survivors by helping them manage emotional, cognitive, and physical challenges.
- Trial name
- CARDIS (NCT07240714)
- Testing
- Digital Support Programme
- Where
- 9 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Ischemic Stroke, Intracranial Haemorrhage
Prospective, Randomized, Parallel-Controlled Study of Brain Computer Interface Integrated Robotic Mirror Therapy for Post-Stroke Upper Limb Motor Function Disorder
This study aims to utilize non-invasive brain-computer interface technology in conjunction with mirror therapy to design a new paradigm for rehabilitation robots to induce compensatory movements on the healthy side in stroke…
- Conditions
- Ischemic Stroke, Intracranial Haemorrhage, Brain-Computer Interfaces, Rehabilitation Exercise
- Trial name
- BCI-RMT (NCT07553416)
- Testing
- Brain computer interface-robotic mirror therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Tiantan Hospital
Tracheostomized Patients, Decanulation
Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients
The goal of this study (exploratory sequential design; mixed-methods study) is to evaluate whether a PERMA-H model mobile-based rehabilitation support program delivered to post-tracheostomy oral cancer patients can improve…
- Conditions
- Tracheostomized Patients, Decanulation, Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Rehabilitation Outcome
- Trial name
- NCT07714967
- Testing
- PERMA-H model mobile-based rehabilitation support program
- Where
- 2 sites in China, Malaysia
- Volunteers
- 100 people
- Sponsor
- Hainan Medical College
HGF, Fibroblast
Effects of Chlorhexidine on Human Gingival Fibroblasts
This prospective in vitro study aims to evaluate the effects of two chlorhexidine-based mouthwash formulations on the survival and function of human gingival fibroblasts (hGFs).
- Conditions
- HGF, Fibroblast, Chlorhexidine, Cytotoxicity
- Trial name
- NCT07669636
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Stroke
Comparative Effects of Telerehabilitation and Clinic Based Constraint Induced Movement Therapy on Upper Limb Function in Sub-Acute Stroke Patients
Stroke constitutes a principal cause of chronic neurological disability globally, frequently precipitating profound upper limb motor impairment that compromises functional autonomy and overall quality of life.
- Trial name
- NCT07604181
- Testing
- Constraint-Induced Movement Therapy within a clinical setting, Constraint-Induced Movement Therapy Via Telerehabilitation
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- University of Faisalabad
Neurological Disorders, Mental Health
ACT for Mental Health in Neurological Disorders
The goal of this clinical trial is to examine the efficacy of this manual for mental health in people with mixed neurological disorders, including post-COVID.
- Conditions
- Neurological Disorders, Mental Health, Executive Function (Cognition), Depression/Anxiety
- Trial name
- NCT06897553
- Testing
- ACT-based group therapy
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Bielefeld University
Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder
Home Play-based Intervention for Parents and Infants
The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of…
- Conditions
- Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
- Trial name
- SPRINT (NCT07716072)
- Testing
- SPRINT Intervention, Waitlist Protocol
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Nanyang Technological University
Lung Cancer (NSCLC)
Postoperative Pulmonary Function Assessment Based on Deep Learning Study
Improvements in low-dose CT screening have led to an increase in early-stage NSCLC diagnoses, with surgical resection-usually lobectomy or segmentectomy-remaining the primary curative option.
- Trial name
- NCT07256457
- Testing
- Segmentectomy, Lobectomy, Bronchoscopic Ablation
- Where
- Hong Kong
- Volunteers
- 192 people
- Sponsor
- Chinese University of Hong Kong
Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI)
The Effect of Mobile-Based Perioperative Education on Urinary Incontinence and Erectile Function After Radical Prostatectomy
This prospective randomized controlled study aims to evaluate the effect of mobile-based perioperative education on postoperative urinary incontinence and erectile function in patients undergoing radical prostatectomy.
- Conditions
- Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI), Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- MPE-RP (NCT07520916)
- Testing
- Mobile-Based Perioperative Education Program, Standard Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Giresun University
Mild Cognitive Impairment (MCI)
A Comparison of the Efficacy of Different Rehabilitation Strategies in Mild Cognitive Impairment
The aim of this study is to conduct a comparative analysis of the effects of two different rehabilitation approaches on cognitive and functional outcomes in older adults diagnosed with mild cognitive impairment (MCI).
- Trial name
- NCT07547111
- Testing
- Dual Task Training, The computer-assisted cognitive rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University - Cerrahpasa
Exercise Adherence, Healthy Aging
Effectiveness of a Smartphone Chatbot to Improve Exercise Adherence in Older Adults
This randomized controlled trial aims to evaluate the effectiveness of a smartphone-based chatbot in improving adherence to a 12-week home-based multicomponent exercise program in community-dwelling older adults.
- Trial name
- EXEBOT (NCT07832097)
- Testing
- Chatbot-Supported Home-Based Exercise Program, Paper-Based Home Exercise Program Mostrar más líneas
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Valencia
General Population (no Specific Condition or Disease)
Brain Function Messures of a Psychological Flexibility Skills Training Based on ACT Over Disordered Eating Behaviors
Overweight and obesity are an increasing tendencies worldwide. Disordered Eating Behaviors (DEBs) are feeding dynamics commonly present on them, as in Feeding Disorders (FD).
- Trial name
- FLEXEAT (NCT07492056)
- Testing
- A Psychological Flexibility Skills Training based on ACT.
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Cancer, Sedentary Behaviour
Feasibility of a Habit-Based Intervention to Reduce Sedentary Behaviour in Cancer Survivors
Cancer and its treatments are associated with long-term side effects including lowered physical strength and quality of life. Decreasing sedentary behaviour improves health outcomes in cancer survivors.
- Trial name
- NCT07694479
- Testing
- Sedentary Behaviour Intervention, Active Control Group
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Toronto
Acute Myeloid Leukemia
A Home-Based Exercise Intervention (CAREFit-BMT) in Improving Heart Function Among Patients With High Risk Acute Myeloid Leukemia Undergoing Stem Cell Transplant
This clinical trial studies how well a home-based exercise intervention called Cardiorespiratory Fitness in Bone Marrow Transplant Program (CAREFit-BMT) works in improving heart function among patients with high risk acute…
- Trial name
- NCT07616921
- Testing
- Aerobic Exercise, Resistance Training, Biospecimen Collection
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Washington
Genitourinary Syndrome of Menopause (GSM), Bacterial Vaginosis
Photobiomodulation for Vaginal Dysfunctions: Home-Based vs Outpatient Treatment
Vaginal disorders, including vulvovaginal candidiasis (VVC), bacterial vaginosis (BV), and genitourinary syndrome of menopause (GSM), are highly prevalent conditions that significantly affect women's quality of life and sexual…
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Bacterial Vaginosis, Vulvovaginal Candidiasis (VVC)
- Trial name
- NCT07697768
- Testing
- Blue LED Photobiomodulation
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Patricia Lordelo
Diabetes Mellitus, Type 2, Diabetic Nephropathies
Impact of AI-Based Breath Ammonia Kidney Function Results on Clinical Pharmacist Medication Recommendations
This retrospective study evaluates whether providing clinicians with artificial intelligence (AI)-based kidney function results from a breath ammonia test can improve the quality of medication recommendations made by clinical…
- Trial name
- NCT07888855
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Shanghai Pudong Hospital
Dysmenorrhea, Primary Dysmenorrhea
The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With Dysmenorrhoea
Dysmenorrhoea is a condition that negatively affects the quality of life in women of many age groups. In girls with dysmenorrhoea in adolescence, there is an effect on school performance, self-confidence-depression problems and a…
- Trial name
- NCT06398990
- Testing
- Cognitive Exercise Therapy Approach, Yoga, Routine Medical Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Acibadem University