Clinical trials: Basic Physiology
Hydrotherapy
Effects of Combining Eccentric and Aquatic Based Exercise on Muscle Function
The study will compare the effects of eccentric resistance training versus eccentric training combined with aquatic plyometric training on muscle function outcomes.
- Trial name
- NCT04977999
- Testing
- Exercise
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Brennan Thompson
Hemiplegic Gait
Microsoft Kinect, Gait Function,Hemineglect, Vestibulo-ocular Training
Gait problems in hemineglect patient post stroke , vestibuloocular training plays a role in improving gait function, gait assessment using a model based study (Microsoft Kinect) for pre and post training assesment.
- Trial name
- NCT03913663
- Testing
- vestibuloocular training, regular exercise training for hemiplegic patients
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Acute Stroke
Effects of a Ketogenic Diet on Acute Stroke
The purpose of this controlled, randomized intervention is to investigate whether a fat-based (ketogenic) diet given for a week has a positive effect on blood sugar, mortality and function in patients hospitalized with acute…
- Trial name
- NCT01997749
- Testing
- Ketocal 4:1 (Nutricia), Control diet: Regular diet offered at the hospitals, Ketogenic meals
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- University of Copenhagen
Healthy Men and Women
Effects of an Organic Plant-rich Diet on Gut Microbiome and Vascular Function (ORGAMIC Pilot Study)
Previous work have shown that consumption of foods rich in polyphenols, such as berries and cocoa, led to beneficial changes in the gut microbiota composition, as well as improvements in biomarkers of cardiovascular disease risk…
- Trial name
- NCT04276974
- Testing
- Organic diet, Non-organic diet
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- King's College London
Mild Cognitive Impairment
Home-Based Dual-Task Training for Older Adults
This project is focused on conducting a home-based, thinking while moving exercise intervention for adults 65 years or older, who have mild cognitive impairment, that will integrate several effective training modalities including…
- Trial name
- NCT05108246
- Testing
- Dual-Task Exercise Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- State University of New York at Buffalo
Mild Cognitive Impairment, Chronic Kidney Diseases
Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity
The purpose of this study is to see if 6 months of home-based walking will improve memory, and brain structure and function, compared to health education in older adults that have chronic kidney disease and mild cognitive…
- Trial name
- EXEC (NCT05655325)
- Testing
- Home-based walking exercise, Attention control
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- Columbia University
Diabetes Mellitus, Type 2, Heat Exposure
Home-based Heat Therapy for Type 2 Diabetes
Insulin resistance and hyperglycemia predispose individuals with type 2 diabetes mellitus (T2DM) to endothelial dysfunction and a greater risk of cardiovascular diseases (CVD).
- Trial name
- NCT05269589
- Testing
- Thermoneutral water, Hot water
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Montreal Heart Institute
Low Back Pain, Pain
Workplace Exercises Versus Home-based Exercises on Pain and Function Among Office Workers With Non-specific Low Back Pain
The study was done to investigate the differences between workplace exercises and home-based exercises on pain, function, quality of life, and posture (pelvic inclination angle and lumbar lordotic angle) among office workers with…
- Conditions
- Low Back Pain, Pain, Function, Office Worker
- Trial name
- NCT07297680
- Testing
- Workplace exercise intervention, Home-based exercise intervention, general education and counseling
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2
Examining the Effect of Exogenous Ketone Supplementation on Glucose Control in Type 2 Diabetes
Ketone bodies are a fuel source and signaling molecule that are produced by the body during prolonged fasting or if an individuals consistently eats a low-carbohydrate "keto" diet.
- Trial name
- NCT05155410
- Testing
- Exogenous Ketone Monoester
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
TBI (Traumatic Brain Injury), Brain Concussion
Dual-Task Exercise for Mild Traumatic Brain Injury (mTBI)
The investigators previously developed a virtual 14-day dual-task walking exercise program and tested its feasibility with individuals with mild traumatic brain injury (mTBI) history.
- Conditions
- TBI (Traumatic Brain Injury), Brain Concussion, Clinical Trial, Rehabilitation
- Trial name
- NCT06037603
- Testing
- Brain & Walk Exercise Every Day (BraW-Day)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Child Behavior, Problem Behavior
Executive Function and Symptom Reduction in Youth Receiving Home-based Treatment With Collaborative Problem Solving
In this project, the investigators will extend prior results of parent-reported executive function growth and symptom reduction in children receiving home-based treatment with the Collaborative Problem Solving treatment approach…
- Conditions
- Child Behavior, Problem Behavior, Executive Dysfunction
- Trial name
- NCT04121650
- Testing
- Collaborative Problem Solving
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Depression
Applied Clinical Neuroscience Care for Self-reported Symptoms of Depression and Cerebellar Function in Adults
Pilot study design that operationalizes the multimodal manner of care while evaluating changes in depression symptoms, dysmetria, and balance for medication non-responders.
- Trial name
- DEP (NCT03997240)
- Testing
- Chiropractic Applied Clinical Neuroscience
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Life University
Autism Spectrum Disorder
Hybrid Computerized EF Training Using Virtual Human Stimuli for Autism
The goal of this pilot clinical trial is to learn the preliminary feasibility and efficacy of a home-based hybrid computerized executive function (EF) training program using social stimuli for autistic individuals.
- Trial name
- NCT07308210
- Testing
- Hybrid computerized executive function training
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Education University of Hong Kong
Pulmonary Hypertension
Mobile Internet-based Remote Home Rehabilitation Improves Prognostic Function and Life Quality in Pulmonary Hypertension
The goal of this clinical trial is to learn the effectiveness of remote home-based exercise rehabilitation using mobile Internet technology for patients with pulmonary hypertension，especically providing early and mid-term results…
- Trial name
- NCT06362382
- Testing
- tele-rehabilitation training, health propaganda and education
- Where
- China
- Volunteers
- 80 people
- Sponsor
- China-Japan Friendship Hospital
Abdominal Surgery
Development of a Patient-Reported Outcome Measure to Assess Recovery After Abdominal Surgery
As surgery enters the era of value-based care, it is advocated that postoperative recovery be measured using patient-reported outcomes (PROs) as they provide a mean to incorporate the patient's perspectives and experiences into…
- Trial name
- NCT03461497
- Where
- 7 sites in United States, Brazil and 3 more
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Metabolic Acidosis, Chronic Kidney Disease
Metabolic Acidosis and Vascular Function in Patients With Chronic Kidney Disease
Cardiovascular disease (CVD) is the leading cause of death in patients with chronic kidney disease (CKD) and large artery damage is a major factor that contributes to death.
- Trial name
- NCT02031770
- Testing
- Sodium bicarbonate, Control
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Acidosis, Cardiac; Deficiency
The Impact of the pH on Cardiac Function in the Critically Ill Patient
Study Title: The Impact of the pH on cardiac function in the critically ill patient Sponsor: King's College Hospital NHS Foundation Trust Chief Investigator: Dr Sancho Rodríguez-Villar IRAS Number: 227870 Hypothesis: Titration…
- Conditions
- Acidosis, Cardiac; Deficiency, Acid Base Disorder
- Trial name
- NCT04231045
- Testing
- PiCCO device cardiac monitoring
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- King's College Hospital NHS Trust
Long COVID
A Web-based Platform to Improve Physical Function, Nutrition, and Mindfulness in Patients With Long COVID
Patients with COVID-19 may experience prolonged physical and psychological symptoms after weeks or months of the infection. This may be caused by a combination of factors including poor nutrition, low physical activity, and lack…
- Trial name
- BLEND (NCT05422924)
- Testing
- Web-based platform. (My Viva Plan)
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University of Alberta
Sexual Distress, Sexual Dysfunctions
Anthesis: A Transdiagnostic Cognitive-Behavioral Therapy (CBT)-Based Approach to Sexual Distress: Testing a Pilot Online Intervention
This pilot study, named Anthesis, evaluates the preliminary efficacy of an online pilot study for sexual distress related to sexual function (SDRSF) in adults.
- Trial name
- Anthesis (NCT06823973)
- Testing
- CBT-based transdiagnostic approach to sexual distress, Waiting list condition
- Where
- 2 sites in Portugal
- Volunteers
- 30 people
- Sponsor
- Grupo Lusófona
Dysphagia, Sleep Apnea, Obstructive
The Effect of Obstructive Sleep Apnea Operations on the Swallowing Function
The investigators hypothesize that partial robotic tongue base resection surgery and / or soft palate surgery, as a treatment for sleep apnea affect the swallowing quality.In order to characterize the dysphagia The investigators…
- Trial name
- NCT03082170
- Testing
- FEES, SDQ, data review
- Volunteers
- 120 people
- Sponsor
- Rambam Health Care Campus