Clinical trials: Basic Physiology, open to volunteers
Stroke
Efficacy of Music-Based Telerehabilitation After Stroke
The goal of this clinical trial is to learn if a music-based telerehabilitation intervention implemented at home works to treat different kinds of neurological deficits caused by stroke.
- Trial name
- NCT06804304
- Testing
- Music-based telerehabilitation
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Teppo Sarkamo
Erectile Dysfunction, Sexual Dysfunction
Male Sexual Function and Sexual Quality of Life in Polygamous Versus Monogamous Marriages
This web-based comparative cross-sectional survey will assess sexual function, sexual quality of life, psychological status, and marital satisfaction among Egyptian men in monogamous and polygamous marriages.
- Trial name
- NCT07783958
- Testing
- Monogamous marital structure, Polygamous marital structure
- Where
- Egypt
- Volunteers
- 1,820 people
- Sponsor
- Al-Azhar University
Congenital Heart Disease, Telerehabilitation
The Effect of Telerehabilitation Exercises in Children With Congenital Heart Disease
This study aims to investigate the effects of functional inspiratory muscle training on physical performance and quality of life in pediatric patients with congenital heart disease.
- Conditions
- Congenital Heart Disease, Telerehabilitation, Functional Inspiratory Muscle Training
- Trial name
- CHD (NCT07854171)
- Testing
- Inspiratory Muscle Training, Functional Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Izmir Democracy University
Foot Diseases
Comparison of the Effects of Virtual Reality-Based Interventions on Foot Function, Foot Pressure, and Balance in Sedentary Individuals
Comparison of the Effects of Virtual Reality-Based Interventions on Foot Function, Foot Pressure, and Balance in Sedentary Individuals
- Trial name
- NCT07260747
- Testing
- VR Biodex Group, Video-Based VR Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Well-Being, Psychological, Loneliness
Physiological, Hormonal, and DNA-based Mechanisms of Psychosocial Stress and Therapeutic Effect
The goal of this trial is to learn if the Groups 4 Health (G4H) intervention is effective in supporting student well-being at the University of Helsinki.
- Trial name
- NCT07152652
- Testing
- Groups 4 health
- Where
- Finland
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Alpha and Beta Thalassemia, Sickle Cell Disease
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
Background: Blood disorders like sickle cell disease and malaria affect many people around the world. Researchers want to learn more about blood disorders.
- Conditions
- Alpha and Beta Thalassemia, Sickle Cell Disease, Malaria, Human Physiology
- Trial name
- NCT03937817
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
Chatbot Intervention Effects on Resting-State Brain Function in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on resting-state brain function in college students with elevated anhedonia and depressive…
- Trial name
- NCT07665216
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Overweight Adults
Effects of a Sugar-Based Synbiotic Product on Cardiometabolic and Intestinal Health (SUGAR-SYN BC3O)
This randomized, double-blind, controlled, crossover study investigates the effects of a sugar-based synbiotic product containing inulin and Bacillus coagulans BC30™ spores in healthy overweight individuals.
- Trial name
- SUGAR-SYN BC3O (NCT07806383)
- Testing
- Sugar-Based Synbiotic Product, Inulin-Containing Sugar Product
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federico II University
Post-Intensive Care Syndrome, ICU Acquired Weakness
Hand and Arm Rehabilitation Using VR
Patients admitted to the ICU due to critical illness often experience physical, mental, cognitive, or social issues. Research indicates that inadequate physical recovery is associated with lower handgrip strength, and hand…
- Trial name
- HANDQUEST (NCT06373341)
- Testing
- VR training for arm and hand rehabilitation
- Where
- Netherlands
- Volunteers
- 108 people
- Sponsor
- Frisius Medisch Centrum
Frailty, Aging
Vivifrail Exercise Program in Nonagenarians: Effects on Function, Muscle, and Cognition
This randomized clinical trial investigates the effects of a home-based multicomponent exercise program (Vivifrail) on physical function, muscle morphology, and cognition in community-dwelling adults aged 90 years and older.
- Conditions
- Frailty, Aging, Cognitive Decline
- Trial name
- Vivifrail (NCT07731529)
- Testing
- Vivifrail multicomponent exercise program
- Where
- 2 sites in Brazil
- Volunteers
- 54 people
- Sponsor
- Federal University of Rio Grande do Sul
Exercise Adherence, Healthy Aging
Effectiveness of a Smartphone Chatbot to Improve Exercise Adherence in Older Adults
This randomized controlled trial aims to evaluate the effectiveness of a smartphone-based chatbot in improving adherence to a 12-week home-based multicomponent exercise program in community-dwelling older adults.
- Trial name
- EXEBOT (NCT07832097)
- Testing
- Chatbot-Supported Home-Based Exercise Program, Paper-Based Home Exercise Program Mostrar más líneas
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Down Syndrome, Trisomy 21
Executive Function Play Opportunities for Children With Down Syndrome
The Executive Function Play Opportunities (EXPO) study is a sequential, multiple assignment, randomized trial (SMART) evaluating adaptive caregiver-mediated intervention pathways for improving executive function (EF) in children…
- Trial name
- EXPO (NCT07792382)
- Testing
- EXPO, EXPO Extended, EXPO Foundations
- Where
- 2 sites in United States, Italy
- Volunteers
- 150 people
- Sponsor
- Colorado State University
Liver Cirrhosis, Liver Cancer
Development of a Set of Auxiliary Decision-making System for the Perioperative Period of Hepatectomy Based on Static CT and Artificial Intelligence.
The study will prospectively recruit patients with chronic liver disease and liver cancer for static CT scans to establish a high-definition CT database.
- Trial name
- NCT07056270
- Testing
- static CT scans
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Cerebral Palsy (CP)
Effect of a Humanoid Robot With Virtual Reality Games to Train Arm Function in Children With Cerebral Palsy - THRIVE Trial
About 60% of children with cerebral palsy (CP) have impaired arm function. Improving arm function requires hundreds of repetitions per day, which is impossible in a single clinical visit.
- Trial name
- THRIVE (NCT06881407)
- Testing
- Robot, Virtual Reality
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Georgia State University
Intact Cognitive Function, MCI
Developing and Testing an AI-Based Cognitive Intervention Program
The goal of this clinical study is to learn if an artificial intelligence (AI)-assisted lifestyle intervention program can help protect memory and thinking skills in adults aged 40 years and older who do not have severe cognitive…
- Conditions
- Intact Cognitive Function, MCI, Mild Dementia
- Trial name
- AICog (NCT07766993)
- Testing
- Lifestyle Intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Research Center for Rehabilitation Technical Aids
Diabetes (DM), Diabetic Ketoacidosis
Phase 1 Trial of Arginine Hydrochloride for the Management of Diabetic Ketoacidosis in Type 2 Diabetes
Diabetic ketoacidosis (DKA) is increasingly recognized in adults with "ketone-prone" type 2 diabetes. In many of these patients, the pancreas can still make insulin but becomes temporarily "stunned" during severe, prolonged high…
- Conditions
- Diabetes (DM), Diabetic Ketoacidosis, Ketosis Prone Diabetes, Hyperglycaemia (Diabetic)
- Trial name
- NCT07167693
- Testing
- Arginine hydrochloride, Sodium Chloride 0.9%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- David K Carroll
Cerebral Palsy (CP)
Neuromuscular Electrical Stimulation and Leap Motion-Based Exercises in Cerebral Palsy
Cerebral palsy (CP) is a group of disorders resulting from a permanent but non-progressive lesion in the developing brain, which affects the development of movement and posture and may lead to activity limitations.
- Trial name
- NCT07311018
- Testing
- Leap Motion-Based Exercise Program, NMES, Conventional Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
AI Care Device
Artificial Intelligence-based Dietary Care System
Patients with rectal cancer complicated by low anterior resection syndrome who undergo anal-preserving surgery may experience severe distress in daily life due to changes in bowel function, thus requiring significant…
- Trial name
- AI DC-system (NCT07637565)
- Testing
- Artificial Intelligence-based Dietary Care System, Routine Care
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Benign Prostatic Hyperplasia
A Smart Wearable Device for Monitoring Urination Function in Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia (BPH) is a common condition that can cause bothersome urination problems and reduce quality of life.
- Trial name
- NCT07357012
- Testing
- Electrical Impedance Tomography (EIT) Wearable Monitoring Device
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Type 2 Diabetes Mellitus (T2DM)
Quinoa Improves Glycolipid Metabolism and Glucose Fluctuation Based on β-Cell Function in Early-stage Type 2 Diabetes
The goal of this clinical trial is to explore whether quinoa diet can improve glycolipid metabolism and glucose fluctuations in patients with early-stage type 2 diabetes mellitus (T2DM) and observe its impact on islet β-cell…
- Trial name
- QIGMAGFBOβFIET (NCT07329231)
- Testing
- Quinoa-based foods
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qilu Hospital of Shandong University