Clinical trials: Basic Science
Basic Science
Influence of Oxytocin on Approach-avoidance Tendencies to Social and Non-social Stimuli
In this study, a randomized, placebo-controlled between-subject design is adopted to investigate the effect of a single-dose of intranasally administered OT on approach-avoidance related motivational tendencies during the…
- Trial name
- NCT04443647
- Testing
- Oxytocin
- Where
- Belgium
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Continuity of Patient Care, Workflow
Development of a Sign-Out Tool to Improve Handoffs in Care
The purpose of this grant is to fund the research necessary to fully understand the impact of this sign-out tool on clinician workflow, quality of sign-out, and continuity of care.
- Conditions
- Continuity of Patient Care, Workflow, Quality of Signout
- Trial name
- NCT01398761
- Testing
- Signout tool
- Where
- United States
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Basic Science
Neural Basis of Sensory Learning: Brain Regions
The purpose of this study is to understand how the sensory and motor areas of the brain work together to keep a person's hand movements accurate (sensorimotor learning).
- Trial name
- NCT05079516
- Testing
- Theta burst transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Indiana University
Covid19, Vaccines
Text-based Interventions to Promote COVID-19 Vaccinations
This study investigates whether and which type of text-based interventions affect the take-up of the COVID-19 vaccine.
- Trial name
- NCT04800965
- Testing
- Patient MyChart Scheduling Link, Patient Educational Video, Enhanced Follow through Message
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Basic Science: Visual Attention in Healthy Participants, Basic Science: Neural Representations of Location
Probing the Role of Feature Dimension Maps in Visual Cognition: Impact of Working Memory Maintenance (Expt 2.3)
How does one know what to look at in a scene? Imagine a "Where's Waldo" game - it's challenging to find Waldo because there are many 'salient' locations in the picture, each vying for one's attention.
- Trial name
- NCT06733467
- Testing
- Stimulus properties: remembered feature
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Healthy Adult Male
Acute Effects of Caffeine on Repeated Sprint Performance and Energy Distribution
The goal of this study is to learn if low-dose caffeinated coffee improves repeated sprint performance and affects energy system contributions in combat sports athletes.
- Trial name
- NCT07596511
- Testing
- Cycling Repeated Sprint Test (6 × 10 s), Breath-by-Breath VO₂ Monitoring - COSMED K5, Capillary Blood Lactate Sampling (non-invasive)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Trabzon University
Obesity
Evaluation of the Effectiveness of Internet Based Nutrition and Physical Activity Education Programme in Adolescents
The purpose of this study to create an educational portal "Genç (e) sağlık" in an attempt to develop a healthy eating habit, increase physical activity and reduce sedentary behavior in order to prevent to overweight gain which is…
- Trial name
- NCT02297919
- Testing
- Effectiveness of Internet Based Obesity Control Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Intrauterine Adhesion, Scar
Clinical and Basic Research on the Necessity of Scar Tissue Resection During Intrauterine Adhesions
TCRA is an important surgical method to restore normal menstrual cycle and improve the outcome of pregnancy.However, postoperative intrauterine adhesion, uterine cavity deformation and difficulty in normal intimal growth…
- Trial name
- NCT05003869
- Testing
- Scar tissue is removed
- Where
- China
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Lili Cao
Basic Life Support
The Effect of Pecha Kucha Presentation for Basic Life Support Training on Students' Knowledge and Practices Levels
Basic Life Support (BLS) is the practice performed to ensure oxygenation of the lungs and pumping of blood from the heart without medication or medical intervention in a person whose breathing and/or heart has stopped (Tiryaki…
- Trial name
- NCT06213961
- Testing
- pecha kucha education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MAİDE YEŞİLYURT
Basic Science
LSD Occupancy of the Serotonin 2A Receptor in the Human Brain
The investigators wish to quantify the relation between administered dose of lysergic acid diethylamide (LSD), plasma LSD levels, and occupancy at the serotonin 2A receptor (5-HT2AR) using [11C]CIMBI-36 positron emission…
- Trial name
- dOccLS (NCT05953038)
- Testing
- Lysergic Acid Diethylamide Tartrate
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Implementation Science
Implementation of Two Transdiagnostic Interventions Based on Emotional Regulation (DBT and UP) for Alcohol Addiction
The aim of this study is to evaluate the dissemination and implementation process of two transdiagnostic psychological interventions (Dialectical Behavioral Therapy for Substance Use Disorders-DBT-SUD and Unified Protocol-UP) to…
- Trial name
- NCT06366100
- Testing
- Dialectical Behavior Therapy for Substance Use Disorder (DBT-SUD), Unified Protocol (UP)
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Inspiratory Muscle Strength
Inspiratory Muscle Warm-up Protocol
The capacity of athletes to demonstrate their abilities to the fullest extent is contingent upon their physical fitness. Oxygen delivery and utilization become crucial during athletic pursuits, as muscle oxygen demand increases…
- Trial name
- NCT06894316
- Testing
- Inspiratory muscle warm-up training, General Warm-up Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Burak Karaca
Pain, Obesity, Childhood
Sumamos Excelencia Project: Implementation of Best Practices in Clinical Practice (Thrid Edition)
There is a gap between research and clinical practice, leading to variability in decision-making. Multifaceted implementation strategies are for improving implementation of best practices.
- Conditions
- Pain, Obesity, Childhood, Breast Feeding, Incontinence, Urinary
- Trial name
- SE24 (NCT06522529)
- Testing
- Multifaceted implementation strategy
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Pregnancy Complications, Preterm Labor
Strengthening Facility-based Intrapartum/Immediate Newborn Care to Reduce Mortality of Preterm Infants in Migori County, Kenya and Busoga Region, Uganda
The purpose of this study is to determine whether a combination of evidence-based strategies can improve intrapartum and newborn care in facilities to reduce mortality among preterm infants.
- Conditions
- Pregnancy Complications, Preterm Labor, PreTerm Birth, Stillbirth
- Trial name
- PTBi-KE-UG (NCT03112018)
- Testing
- data strengthening, modified Safe childbirth checklist - control, modified Safe childbirth checklist - enhanced
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 102,988 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Neurodevelopmental Disorders
WHO Mental Health Gap Action Program (mhGAP) for Improving Child Mental and Behavioral Disorder Service Quality in China
The goal of this clinical trial is to learn if the adapted mhGAP intervention guide (mhGAP-IG) can improve quality of child mental and behavioral disorders (CMBDs) services in China.
- Trial name
- mhGAP (NCT06702410)
- Testing
- mental health gap action program intervention guide (mhGAP-IG)
- Where
- 9 sites in China
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Nutrition, Healthy
Effect of Transtheoretical Model Based Nutrition Education on Sustainable Nutrition Behavior in Adolescents
The aim of this intervention study is to evaluate the effect of sustainable nutrition education based on the Transtheoretical Model (TTM) on adolescent behavior.
- Trial name
- NCT06583499
- Testing
- Sustainable nutrition education based on the transtheoretical model
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Obstructive Sleep Apnea
Obstructive Sleep Apnea and Genes Expression
Obstructive sleep apnea is a multi-component disease. This study will test the hypotheses that hypoxia per se modulates gene expression in animal model of sleep apnea and these results may be translated with alterations that…
- Trial name
- HIP (NCT01392339)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Associacao Fundo de Incentivo a Psicofarmcologia
Headache
Carbachol´s Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
To investigate headache score and accompanying symptoms during and after infusion of carbachol.
- Trial name
- NCT00357864
- Testing
- carbachol
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Adolescent Behavior, Parenting
Implementing a Church-based Parenting Intervention for Hispanics
The current investigation consists of the implementation and modest refinements of a culturally adapted version of the evidence-based PT intervention known as GenerationPMTO.© The adapted intervention, CAPAS-Youth, is primarily…
- Trial name
- NCT05291481
- Testing
- CAPAS-yOUTH
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin