Clinical trials: Basic Science
Chronic Disease Prevention
Engaging Partners in Caring Communities
The goal of the EPICC observational study is to learn about capacity to implement evidence-based health promotion programs (EBPs) in congregations that are offered semi-structured technical assistance (TA).
- Trial name
- EPICC (NCT06932549)
- Testing
- Technical assistance is designed to integrate Expert Recommendations for Implementing Change (ERIC) strategies, and Getting To Outcomes-TA.
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tennessee State University
Health Knowledge, Attitudes, Practices
The Science Tooth Fairy: A Randomized Trial of a Storytelling-Based Educational Intervention to Promote Primary Tooth Donation in a Pediatric Setting
Study Overview Primary ("baby") teeth are unique biological samples because they can permanently store information about a child's early life health and development.
- Trial name
- STF RCT (NCT07711301)
- Testing
- Science Tooth Fairy Narrative, Cavities vs. Toothpaste, book by Didi Dragon
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy Children
Outdoor Science Education and Child Well-being in Primary Schools: Protocol for a Cluster Randomized Controlled Trial on Learning, Connection to Nature, Eco-anxiety, and Stress
The goal of this randomized controlled trial is to learn if an outdoor science education intervention can improve primary school students' learning and well-being when compared to an indoor classroom-based science education…
- Trial name
- Bio-Explo (NCT07147634)
- Testing
- Outdoor science education, Indoor classroom-based science education
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Trauma, Sexual
PHF Problematic Sexual Behavior of Youth Family Engagement
Efficacious child mental health services are only helpful if families engage in services; however, as many as 75% of families in need never establish contact with a mental health professional and greater than half of families…
- Trial name
- NCT04902287
- Testing
- Training Intervention for the Engagement of Families (TIES)
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Educational Problems
Effectiveness of Haptic Technology in Teaching Urinary Catheterization Skill
Background: Haptic systems represent the highest level of computer based education technologies and enable students to learn at the highest level.
- Trial name
- NCT04653233
- Testing
- 3D Systems Touch Haptic Simulator
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Assessment, Self, Simulation-Based Education
Brief Title: Portable 3D Visual Material-Supported Simulation Training for Cervical Dilation Assessment
This randomized controlled trial aimed to evaluate the effectiveness of simulation-based education supported by a portable and mobile three-dimensional (3D) visual material on university students' knowledge of cervical dilation…
- Trial name
- NCT07705503
- Testing
- Portable 3D Visual Material-Supported Simulation Training, Standard Education
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Marmara University
AI (Artificial Intelligence)
Scientific Validity Assessment and Optimization of AI-Generated A3/A4 Type Questions for the Chinese Medical Licensing Examination
This is a cross-sectional study that primarily employs quantitative analysis, supplemented by qualitative assessment. The research is conducted in two stages: Phase I consists of a model performance comparison experiment, and…
- Trial name
- NCT07505862
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Child Maltreatment
Effectiveness and Cost-effectiveness of Coaching Models to Promote Implementation of an Evidence-based Parenting Program
The proposed study will compare purveyor coaching (conducted by National SafeCare Training and Research Center (NSTRC)) to local coaching that is supported by the purveyor (NSTRC).
- Trial name
- NCT01791777
- Testing
- SafeCare Coaching
- Where
- 10 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Anxiety Symptoms, Post-traumatic Stress Symptoms
Improving Student Mental Health Through a Universal Trauma-Informed Intervention
The goal of this trial is to identify the most effective ways for schools to deliver RAP Club, a universal school-based mental health intervention.
- Conditions
- Anxiety Symptoms, Post-traumatic Stress Symptoms, Depressive Symptoms, Behavioral Problems
- Trial name
- PPP (NCT07842432)
- Testing
- RAP Club Delivered by a School Clinician, RAP Club Delivered by a Teacher, Standard Supervision
- Where
- 3 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Colorectal Carcinoma
Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)
Although implementation intentions (I2)-based tools enhance colorectal cancer (CRC) screening uptake, prior studies have not tested their implementation into routine primary care delivery.
- Trial name
- (PB-iCRC) (NCT06682650)
- Testing
- NPT-PLA, Usual Quality Improvement
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Lung Cancer, Head and Neck Cancer
A Feasibility Study to Further the Development of Lung Cancer-based Precision Medicine
The purpose of this study is to further advancements in biospecimens (blood cellular free component, e.g., plasma, serum, tissue, urine), in order to develop precision medicine, for lung cancer management and lung cancer…
- Trial name
- NCT02597738
- Testing
- Fresh tissue biopsy, Blood/Urine Sample Collection
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Spinal Cord Injuries, Rehabilitation
Feasibility of Home-Based Rehabilitation on Body Composition, Some Anthropometric Measures and Muscular Strength After Interruption 4-5 Years of Spinal Cord Injury: Serial Cases Study on ISIS War Survivors in Iraq
Feasibility of Home-Based Rehabilitation on Body Composition, some Anthropometric Measures and Muscular Strength after interruption 4-5 years of Spinal Cord Injury: Serial Cases Study on ISIS War Survivors in Iraq Summary…
- Conditions
- Spinal Cord Injuries, Rehabilitation, Exercises
- Trial name
- HBRP-SCI (NCT06230627)
- Testing
- Home-Based Rehabilitation rogram
- Where
- Tunisia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Mosul
Child Nutrition Sciences
Nutritive Effects of a Cow's Milk Based Formula Fed to Young Children
This study aims to determine if a cow's milk-based formula with added nutrients has an effect on memory, reaction time, strategy or other cognitive development indicators in children 4-5 years of age.
- Trial name
- NCT02776592
- Testing
- Cow's milk-based formula with added nutrients, Cow's milk-based formula
- Where
- Brazil
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Headache, Migraine
Carbon Monoxide Migraine-inducing Effects in Patients With Migraine Without Aura.
To investigate headache score and accompanying symptoms during and after inhalation of carbon monoxide.
- Trial name
- NCT03075020
- Testing
- Carbon monoxide, AIR
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Substance Abuse
Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education
Our primary goal is to conduct a pilot study of the effects of a new potential strategy for youth substance abuse prevention - science-based drug education integrated into the high school science curriculum.
- Trial name
- NCT00612482
- Testing
- drug prevention curriculum
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cardiovascular Diseases, Physical Inactivity
MoST-Influenced Behavioral Intervention for Walking
This study is a randomized, factorial experiment using the basic Science of Behavior Change (SOBC) approach to efficiently test the effects of four distinct behavior change techniques (BCTs), goal setting, action planning, self…
- Trial name
- NCT05425641
- Testing
- Goal Setting, Action Planning, Self-Monitoring of Behavior
- Where
- United States
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Heat Exposure, Blood Volume
Heat Acclimation in Females
Heat acclimation is when you repeatedly exposure yourself to heat so that your body adapts and better tolerates heat. This project will determine if completing a heat acclimation maintenance period after heat acclimation is more…
- Conditions
- Heat Exposure, Blood Volume, Cardiac Output
- Trial name
- NCT06551168
- Testing
- Heat exposure, Control group
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Trinity Western University
HIV
Streamlining Telehealth for Expanded PrEP Utilization Through Community Partnerships
The goal of this study is to learn if STEP-UP (Streamlining Telehealth for Expanded PrEP Utilization through community Partnerships) works to expand access to PrEP for people who could benefit from HIV prevention tools.
- Trial name
- STEP-UP (NCT07246057)
- Testing
- STEP-UP, Philadelphia TelePrEP Program Direct-to-Consumer Model
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Firefighters
PeerOnCall: Implementing and Evaluating App-Based Peer Support in Canadian Fire Services
The goal of this clinical trial is to test how best to implement a mobile peer support app called PeerOnCall in Canadian fire services. The main questions it aims to answer are: 1.
- Trial name
- NCT07199387
- Testing
- App Users (Structured Implementation), App Users (Standard Implementation)
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cardiac Function in Young Athletes
Study to Assess the Effect of OXYJUN on Ejection Fraction and Markers of Cardiovascular Injury
Young athletes are usually regarded as a special subgroup of healthy individuals with a unique lifestyle who are apparently invulnerable and often capable of extraordinary physical achievement.
- Trial name
- Enduoxy (NCT02207101)
- Testing
- E-OJ-01 (OXYJUN)
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.