Clinical trials: Behavior, Addictive
Nicotine Dependence
Brain Activity and Smoking Cessation
In the current study, the investigators propose to test: (1) whether brain activation and connectivity in a resting state, assessed by ASL perfusion MRI, BOLD fMRI, and diffusion tensor imaging (DTI) predicts smoking relapse, and…
- Trial name
- NCT01186055
- Testing
- Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Opiate Dependence, Cocaine Dependence
Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo Using 11UCB-J PET
This study aims to measure synaptic density in the brains (including in ventral striatum [VS] and medial prefrontal cortex [mPFC]) of abstinent subjects with Cocaine Use Disorder (CUD) or Opiate Use Disorder (OUD) as compared to…
- Trial name
- NCT03527485
- Testing
- 11UCB-J PET Scan
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Yale University
Weight Regain After Bariatric Surgery and Food Addiction, Eating Behavior
Intuitive Eating Intervention After Bariatric Surgery
This study evaluated the validity and reliability of the Turkish version of the Intuitive Eating Scale-2 (IES-2) in individuals who had undergone bariatric surgery and examined the effects of a 6-week online intuitive eating…
- Conditions
- Weight Regain After Bariatric Surgery and Food Addiction, Eating Behavior, Body Image
- Trial name
- NCT07859449
- Testing
- Intuitive Eating Intervention, Standard Nutritional Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Amphetamine Addiction
The Novel Addiction Assessment Study in Synthetic Drugs Addiction
The purpose of this research is to develop an objective assessment based on the virtual reality techniques which is used for evaluate addiction severity.
- Trial name
- NCT02950376
- Testing
- DSM-5 +Virtual reality-based addiction assessment system, Virtual reality-based addiction assessment system
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Knowledge Gaps, Attitudes
Addiction Psychoeducation for Canadian Muslims
The Canadian Muslim Addiction Program (C-MAP) was designed as a pilot randomized controlled study using quantitative and qualitative methods to evaluate culturally and spiritually adapted addiction psychoeducation.
- Conditions
- Knowledge Gaps, Attitudes, Stigma of Mental Illness, Help-seeking Intention
- Trial name
- NCT07865104
- Testing
- Culturally sensitive addiction psychoeducation program, Secular
- Where
- Canada
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Opioid Addiction
Integrating Support Persons Into Recovery
INtegrated Support Persons Into Recovery (INSPIRE) is a 4-year research project that tests whether integrating a patient's support person into a patient's treatment with Buprenorphine/Naloxone can improve outcomes.
- Trial name
- INSPIRE (NCT04239235)
- Testing
- CRAFT
- Where
- 6 sites in United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Stanford University
Self Efficacy
Substance Use Risk and Solution-Focused Approach
Although substance abuse is the subject of serious struggles on the basis of individuals and countries, its rate of spread cannot be stopped and it creates an agenda with new people added every day.
- Trial name
- NCT06732206
- Testing
- Short Solution Focused Approach Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ufuk DOĞAN
Muscle Weakness, Smartphone Addiction
Effect of Scapular Stabilization Exercises on Scapular Muscles Strength and Kyphosis Index in Smartphone Users
This study will be conducted to investigate the effect of scapular stabilization exercises on scapular muscles strength (serratus anterior, lower fibers of trapezius, rhomboid major and minor), pain intensity level and kyphosis…
- Trial name
- NCT05437367
- Testing
- Scapular Stabilization exercises, Postural correction exercises
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alcohol Dependence
Binge Drinking And Addiction : Case-Control Study in Hospital
Case Control Study : Objective: Frequent Binge drinking during 18-25 years is a risk factor of alcohol addiction in adulthood (25-40 years) Hypothesis: 25% of frequent binge drinking, OR = 2, power 80%, alpha risk : 5% 126 Cases…
- Trial name
- BACH (NCT03204214)
- Where
- France
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Marie-Pierre TAVOLACCI
Internet Addiction, Game Addiction, Video
Motivational Interviewing and Addiction
The increasing use of the internet makes understanding games among adolescents different by moving it to the virtual environment and increases the digital game addiction risk.
- Trial name
- MI-IA-DGA (NCT06721702)
- Testing
- Motivational interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Gazi University
Pharynx Cancer, Larynx Cancer
Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in a High Risk Population
Randomized multicenter trial to assess the impact of a screening program for heavy alcohol drinkers and smokers treated in alcohol addiction clinics on upper aerodigestive tract cancer mortality.
- Conditions
- Pharynx Cancer, Larynx Cancer, Oral Cavity Cancer, Oesophageal Cancer
- Trial name
- NCT00359645
- Testing
- Screening by head and neck clinical examination with a fiberoptic nasolaryngoscopy and an oesopharyngeal brush biopsy annually during 3 years
- Where
- 35 sites in France
- Volunteers
- 1,993 people, healthy volunteers welcome
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Alcohol Dependence, in Remission, Addiction, Alcohol
Does Treatment With GLP-1 Reduce Alcohol Intake in Patients With Alcohol Dependence?
The study is a double-blinded, randomized, placebo-controlled, 26-weeks clinical trial. The objective of the trial is to investigate the effects of the GLP-1 receptor agonist Bydureon® (exenatide) vs.
- Trial name
- EXALT (NCT03232112)
- Testing
- Exenatide 2 MG Injection, BD PosiFlush (saline)
- Where
- Denmark
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Anders Fink-Jensen, MD, DMSci
Addiction
Linking fMRI to Mobile Technologies in Addiction Research: Pathophysiology of Executive Deficits, Craving and Substance Use
120 individuals with alcohol, cannabis or nicotine dependence as well as healthy controls will be administered a whole-brain imaging exam.
- Trial name
- MobiCogIm (NCT02334956)
- Testing
- Brain MRI
- Where
- 2 sites in France
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Addiction Chemical, Use, Substance
Substance Use Disorder in Chemsex Practice
The main aim of this descriptive cross-sectional study is to assess the prevalence of chemsex substance use disorder among chemsexers via an online self-questionnaire.
- Trial name
- TU CHEMSEX (NCT06476873)
- Testing
- Online self-questionnaire.
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Nicotine Dependence, Nicotine Withdrawal
Progesterone and Brain Imaging Study
Male and female smokers were recruited to undergo 2 phases of smoking cessation. Each phase was 4 days long and involved 3 brain-imaging scans, blood draws and an intervention involving progesterone or a matched placebo.
- Trial name
- NCT01954966
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alcohol Addiction
Study of the Opioid Modulation of the Effect of Alcohol on the Dopaminergic Reward System
About 10% of the calculable loss of health and quality of life in industrial countries can be attributed to excessive alcohol consumption.
- Trial name
- NCT03854942
- Testing
- Naltrexone
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Assessment, Self, Cerebral Palsy
Assessment by Surface Electromyography in Cerebral Palsy Footballers
Adapted sport is constantly evolving thanks to the technological and scientific advances in the field of sports that are being developed in our era.
- Conditions
- Assessment, Self, Cerebral Palsy, Technology Addiction
- Trial name
- NCT06151873
- Testing
- Adapted sport
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Internet Addiction Disorder
Evaluation of a Therapeutic Education Application in the Treatment of Young People with Moderate or Problematic Screen Use
This single-center, controlled, and randomized study evaluates the effectiveness of the Phonix Care app in regulating screen use among young people aged 11 to 25.
- Trial name
- PHONIX CARE (NCT06648538)
- Testing
- Phonix Care
- Where
- France
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Smoking Cessation, Nicotine Addiction
Nicotine Receptor Levels and Smoking Cessation
The investigators propose to use positron emission tomography (PET) imaging to determine whether nicotinic receptor availability at pretreatment predicts smoking cessation success.
- Trial name
- NCT01788943
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Addiction, SMARTPHONE OWNER
Mobile Restriction on Dopamine Transporter
Restriction of mobile phone use for 2wks and undergo PET scanning for DAT bindinng. Free use of mobile phone use for 2wks and undergo PET scanning for DAT bindinng.
- Trial name
- NCT07663474
- Testing
- Mobile phone restrction
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital