Clinical trials: Behavior, Addictive, open to volunteers
Smoking (Tobacco) Addiction, Smoking ( Cigarette)
Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt
Smoking is the leading preventable cause of death in the United States, and quitting is especially difficult for couples who both smoke.
- Conditions
- Smoking (Tobacco) Addiction, Smoking ( Cigarette), Tobacco, Tobacco Abstinence
- Trial name
- NCT07553962
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver
Cocaine Use Disorder, Cocaine Dependence
Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction
The goal of this clinical trial is to learn about the effects of the combination of ketamine and realtime functional magnetic resonance imaging (fMRI) neurofeedback training in individuals with cocaine use disorder.
- Trial name
- Co-Boost (NCT06125054)
- Testing
- Ketamine, real-time fMRI neurofeedback training
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Dr. med. Marcus Herdener
Smart Phone Addiction, Craniovertebral Angle
Correlation Between Smart Phone Overuse, Craniovertebral Angle, Cervical Muscle Endurance and Temporomandibular Proprioception in Adolescents
The study was done to: 1. Investigate the correlation between smart phone overuse and craniovertebral angle in adolescents. 2. Investigate the correlation between smart phone overuse and cervical muscle endurance in adolescents.
- Conditions
- Smart Phone Addiction, Craniovertebral Angle, Temporomandibular Proprioception, Adolescents
- Trial name
- NCT06861751
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Cairo University
Substance Use, Harm Reduction
A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students
The primary goal of this study is to test the effectiveness of the iDECIDE (Drug Education Curriculum: Intervention, Diversion, and Empowerment) curriculum, a novel drug education and diversion program, in approximately 300…
- Conditions
- Substance Use, Harm Reduction, Adolescent Behavior
- Trial name
- NCT06115746
- Testing
- iDECIDE
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Adults (Male and Female Subjects) With Tobacco Dependence
Direct Transcranial Electrical Stimulation in Tobacco Addiction (tDCS)
In summary, there are currently many therapeutic tools for achieving some degree of control or even cessation of tobacco addictive use.
- Trial name
- tDCS (NCT04209153)
- Testing
- Transcranial Direct Current Stimulation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Addictive Behaviors, Emotion Regulation
A Novel Adaptation of the Unified Protocol (UP) as a Transdiagnostic Intervention for Emotional Disorders in Addictive Behaviors
This study aims to pilot a psychological intervention protocol designed for individuals who use substances and who experience difficulties in emotion regulation.
- Trial name
- UP-TIED-AB (NCT07738081)
- Testing
- Transdiagnostic cognitive-behavioral therapy, Treatment as usual
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Oviedo
Toxicomania
Pharmacokinetic Modeling of Methadone
The management of patients with opioid addiction is a challenge insofar as many distractors or variability factors can interfere with the control of the addiction, whether they are psychological, psychiatric, environmental…
- Trial name
- PKMETHAHOME (NCT05490732)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Opioid-use Disorder
Smartphones for Opiate Addiction Recovery
Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus…
- Trial name
- SOAR (NCT05033028)
- Testing
- Smartphone app
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- NYU Langone Health
Alcohol Use Disorder, Stress Reaction
Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
The goal of this observational study is to investigate longitudinal stress response profiles and adaptive versus non-adaptive stress responses in alcohol use disorder.
- Conditions
- Alcohol Use Disorder, Stress Reaction, Social Stress, Craving
- Trial name
- A03 (NCT06105853)
- Testing
- Trier Social Stress Test, Barlab Cue-Exposure, Functional magnetic resonance imaging
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Addictive Behaviors, Internet Addiction Disorder
Is Craving a Central Criterion for Diagnosing a Behavioral Addiction?
This study is a cross-sectional observational study designed to evaluate the diagnostic criteria for behavioral addictions (gambling, online video game disorder, screen addiction, food addiction, and pathological use of sex…
- Conditions
- Addictive Behaviors, Internet Addiction Disorder, Gambling, Technology Addiction
- Trial name
- CRIBA (NCT07854912)
- Testing
- Questionnaires, Telephone interview
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Tobacco Smoking, Harm Reduction
Smoking Harm Reduction Using E-cigarettes and Cytisine
Smoking remains the leading cause of preventable death globally, with high prevalence in disadvantaged populations despite access to free nicotine replacement therapy (NRT) and counseling through Ontario's STOP Program.
- Conditions
- Tobacco Smoking, Harm Reduction, Nicotine
- Trial name
- SHRECC (NCT07274475)
- Testing
- E-cigarette e-liquid, Cytisine
- Volunteers
- 6,000 people
- Sponsor
- Centre for Addiction and Mental Health
Nicotine Dependence, Transcranial Magnetic Stimulation
Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)
The goal of this clinical trial is to learn if a combination of varenicline and enhanced accelerated Transcranial Magnetic Stimulation (aTMS) works to help adults quit using nicotine products.
- Conditions
- Nicotine Dependence, Transcranial Magnetic Stimulation, Vaping, Smoking Cessation
- Trial name
- V-TMS (NCT07145866)
- Testing
- Varenicline, Transcranial Magnetic Stimulation, Nicotine Cessation Counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention
A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school…
- Conditions
- E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
- Trial name
- NCT07460622
- Testing
- Virtual Reality E-Cigarette Prevention Program
- Where
- United States
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- Yale University
Problematic Internet Use
Group-based IMPROVE Therapy for Problematic Internet Use in University Students
Problematic internet use (PIU) is a growing behavioral health concern among university students. This study aims to evaluate the effectiveness and psychological mechanisms of "IMPROVE," a manualized, multimodal group-based…
- Trial name
- IMPROVE-PIU (NCT07434778)
- Testing
- IMPROVE Program, Digital Psychoeducation Newsletters
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Sir Run Run Shaw Hospital
Behavioral Addiction
PARCA (a Digital Tool) to Improve Justice and Health
The purpose of this study is to assess the effectiveness of the Probation/Parole and Reentry Coach Application (PARCA)-a mobile application that allows justice-involved people to set and manage personal goals to support…
- Trial name
- Parca (NCT07199374)
- Testing
- PARCA
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- George Mason University
Opioid Use Disorder, Chronic Pain
Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine
Chronic pain is common in individuals with opioid use disorder (OUD) and the first-line treatment, Medication for OUD (MOUD), does not address the considerable functional impairments associated with chronic pain.
- Trial name
- NCT07361432
- Testing
- Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT), Enhanced Treatment as Usual (ETAU)
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- VA Office of Research and Development
E-cigarette Use, Cigarette Smoking Risk
An Online Intervention to Reduce E-cigarette Use and Cigarette Smoking Risk in Adolescents
The goal of this clinical trial is to learn if a brief digital intervention can reduce e-cigarette use and prevent cigarette smoking initiation in teenagers ages 12-17.
- Trial name
- NCT07624292
- Testing
- Virtual Intervention for Behavioral Empowerment (VIBE)
- Volunteers
- 150 people
- Sponsor
- University of Southern California
Mechanical Neck Pain, Forward Head Posture (FHP)
The Association Between Smartphone Overuse and Mechanical Neck Pain Among Galala University Students
This study explores the relationship between smartphone overuse and mechanical neck pain among university students offers key value for health promotion in academic settings by developing targeted strategies and preventive…
- Conditions
- Mechanical Neck Pain, Forward Head Posture (FHP), Upper Cross Syndrome (UCS)
- Trial name
- CFME/ CVA/ UCS (NCT07879313)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Addiction, SMARTPHONE OWNER
Mobile Restriction on Dopamine Transporter
Restriction of mobile phone use for 2wks and undergo PET scanning for DAT bindinng. Free use of mobile phone use for 2wks and undergo PET scanning for DAT bindinng.
- Trial name
- NCT07663474
- Testing
- Mobile phone restrction
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Alcohol Addiction, Alcoholism
A Trial to Investigate the Effects of Cannabidiol Plus Naltrexone on Alcohol Craving in Patients With Alcohol Dependence
Alcohol addiction (AD) is a chronic relapsing disorder with currently limited pharmacological treatment options. Alcohol craving, a hallmark symptom of AD that drives relapse in patients, is only insufficiently treated by…
- Trial name
- ICONICplus (NCT06845124)
- Testing
- Cannabidiol capsules, Naltrexone (drug)
- Where
- 2 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Central Institute of Mental Health, Mannheim