Clinical trials: Behavior Changes, open to volunteers
Stress, Psychological, Depression and/or Anxiety in the Mild-to-moderate Range
Testing Adapted Self-Help Plus (SH+) for Stress and Well-Being in International Students at a U.S. University
The goal of this clinical trial is to learn if an adapted version of Self-Help Plus (SH+), a stress management program developed by the World Health Organization, can reduce stress and improve well-being in international students…
- Conditions
- Stress, Psychological, Depression and/or Anxiety in the Mild-to-moderate Range, Loneliness, Adjustment, Psychological
- Trial name
- NCT07188467
- Testing
- Digitized SH+
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The New School
Postpartum Weight Retention, Overweight and Obesity
Time-restricted Eating for Postpartum Weight Loss
This study is being done to assess the feasibility and acceptability of a time-restricted eating intervention among postpartum women with overweight/obesity.
- Trial name
- Time4Mom (NCT06491537)
- Testing
- Early Time-Restricted Eating (eTRE), Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Cognitive Wellness, Healthy Aging
MEVA Cognitive Wellness Platform Study for Adults
The goal of this observational study is to evaluate the reliability, usability, and feasibility of the MEVA Cognitive Wellness Platform in community-dwelling adults aged 55 to 75.
- Conditions
- Cognitive Wellness, Healthy Aging, Age-Related Cognitive Change, Aging
- Trial name
- MEVA (NCT07595250)
- Testing
- MEVA Cognitive Wellness Platform
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mentage LLC
Colorectal Neoplasms, Sedentary Behavior
An Intervention to Reduce Sedentary Behavior and Promote Physical Activity in Colorectal Cancer Chemotherapy
This single-group feasibility study develops and evaluates an intervention designed to reduce sedentary behavior and promote physical activity in patients with colorectal cancer undergoing chemotherapy.
- Trial name
- NCT07845877
- Testing
- Sedentary behavior reduction intervention for patients with colorectal cancer undergoing chemotherapy
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Weight Loss, Weight Gain
Time Restricted Eating for WeIght LoSs MainTenance-2
The TWIST 2.0 Study is a 12-month, 2-arm RCT in adults with recent weight loss. We will examine the efficacy of TRE on weight (Aim 1a) and fat mass (Aim 1b) regain, and describe changes in subjective appetite following a…
- Conditions
- Weight Loss, Weight Gain, Weight Loss Maintenance
- Trial name
- TWIST-2 (NCT07190170)
- Testing
- TRE, Weight-Loss Maintenance Advice
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- NYU Langone Health
Disordered Eating Behaviors, Binge Eating
Enhanced Cue Exposure Therapy for Negative Emotional Eating
The current study aims to evaluate the efficacy of Enhanced Cue Exposure Therapy (E-CET) in reducing negative emotional eating (NEE), compared to an active control intervention, behavioral lifestyle intervention (BLI), in a…
- Trial name
- NCT06012045
- Testing
- Enhanced Cue Exposure Therapy, Behavioral Lifestyle Intervention
- Where
- Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Burns, Pain, Procedural
Virtual Reality for Pain and Fear in Children With Burns
Burn injuries are very painful for children, especially during dressing changes when the wound is cleaned and re-bandaged. This procedure, while necessary, can cause pain, fear, and distress that may make children afraid of…
- Conditions
- Burns, Pain, Procedural, Pain, Acute, Fear
- Trial name
- VR-PFB (NCT07740980)
- Testing
- Virtual Reality (VR) Distraction, Standard Burn Dressing Care
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Craniopharyngioma
Food Preferences and Craniopharyngiomas
The hypothalamus plays a key role in regulating appetite, satiety, and energy balance. When tumors such as craniopharyngiomas develop in this region, they can disrupt these mechanisms and lead to a form of severe weight gain…
- Trial name
- PREFAMHYPO (NCT07301554)
- Where
- France
- Volunteers
- 346 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Caregiver
Mindfulness-based Lifestyle Modification Programme for Caregivers of People With Neurological Disorders
Over 80% of caregivers for individuals with neurodegenerative diseases (ND) engage in significant risk behaviors, particularly physical inactivity, which increases the risk of cardiometabolic diseases (CMD) by 30% and reduces…
- Trial name
- B-Mindful-Life (NCT07342140)
- Testing
- In-Person Mindfulness-based Group Sessions, Ecological Momentary Interventions (EMI), In-person Lifestyle Education Session
- Where
- Hong Kong
- Volunteers
- 236 people
- Sponsor
- The University of Hong Kong
Multiple Sclerosis
Physical Activity Intervention for Individuals Newly Diagnosed With MS
The proposed study is a parallel-group randomized controlled trial (RCT) designed to establish the behavioral mechanism underlying a 16-week physical activity (PA) behavioral intervention through its effects on the…
- Trial name
- ActivNMS (NCT07731659)
- Testing
- COM-B-based Physical Activity Behavior Change Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Physical Activity, Sedentary Behavior
Teen Mom Study Feasibility Trial
The proposed multicomponent digital health intervention has the potential to significantly impact the trajectory of maternal health in a rural, pregnant, Black adolescent population with the highest risks for cardiometabolic…
- Conditions
- Physical Activity, Sedentary Behavior, Gestational Weight Gain, Social Determinants of Health
- Trial name
- NCT05843903
- Testing
- #BabyLetsMove
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Heat Illness, Quality of Life
Structural Heat Adaptation and Education in Rural Setting
This study aims to understand whether simple, low-cost interventions, such as improved home cooling, practical advice, and minor home modifications, can help protect people's health and quality of life during periods of extreme…
- Trial name
- SHAPES (NCT06983483)
- Testing
- Community education and awareness, Participatory local structural and environmental heat mitigation solutions
- Where
- Pakistan
- Volunteers
- 7,128 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Body Temperature Changes, Heat Stress
Progressive Heat Exposure and Physiological Strain
Occupational heat-stress guidelines are commonly based on the level of environmental heat exposure and are largely derived from studies conducted under constant environmental conditions.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07847437
- Testing
- Constant Heat Exposure, Progressively Increasing Heat Exposure
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Depression
fMRI Accelerated TMS Depression
This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in Major Depressive Disorder…
- Trial name
- NCT06562153
- Testing
- Neuroimaging with Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Weight Loss, Food Selection
Identifying Changes in Food Behaviors Associated With Beginning GLP-1 Medication
In recent years, GLP-1 medications have become a widely employed approach by physicians to address weight concerns in patients and lead to weight loss.
- Trial name
- NCT06843512
- Testing
- GLP-1 Medication Initiation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Penn State University
Overweight or Obesity, Physical Activities
An Innovative Care Model Integrating Mobile Health Support to Promote Weight Management in Adults With Overweight or Obesity
The objective of this clinical trial is to evaluate whether an innovative care model integrating mobile health (mHealth) support improves weight management in adults with overweight or obesity.
- Conditions
- Overweight or Obesity, Physical Activities, Healthy Diet, Weight Change
- Trial name
- NCT06996431
- Testing
- EMA-based weight management intervention, Minimal Intervention
- Where
- 3 sites in Hong Kong
- Volunteers
- 876 people
- Sponsor
- The University of Hong Kong
Obesity, Solid Neoplasm
Weight Management in Obese Cancer Patients During Curative Active Treatment
This is a feasibility study intervention to fifty cancer patients with obesity and with newly diagnosed stage II-IV solid tumors undergoing curative treatment recruited at the Catalan Institute of Oncology (ICO) in L'Hospitalet…
- Conditions
- Obesity, Solid Neoplasm, Stage II-IV, Curative Treatment
- Trial name
- CANOBESE (NCT07058207)
- Testing
- Multimodal weight management program
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge
Oral Potentially Malignant Disorders, Oral Lichen Planus
Salivary IL-8 and Serum IL-6 as Biomarkers for Oral Potentially Malignant Disorders in Smokers and Never-Smokers
The goal of this observational study is to learn whether two inflammatory proteins, interleukin-8 (IL-8) measured in saliva and interleukin-6 (IL-6) measured in blood serum, can help distinguish adults with oral potentially…
- Conditions
- Oral Potentially Malignant Disorders, Oral Lichen Planus, Oral Leukoplakia, Oral Squamous Cell Carcinoma
- Trial name
- NCT07915570
- Testing
- Salivary IL-8 and Serum IL-6 Measurement
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Fasting, Dietary Fibre
Combining Fasting and Fibre Interventions to Optimise Their Gut Microbiome-mediated Health Benefits
This study builds on the knowledge that fasting provides metabolic health benefits and that prebiotic interventions can enhance the gut microbiome's metabolic output to likewise improve host health.
- Conditions
- Fasting, Dietary Fibre, Gut Microbiome, Metabolism Changes
- Trial name
- CoFFIe (NCT07691736)
- Testing
- Fibre Arm, Control Arm
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Buchinger Wilhelmi Development & Holding GmbH
Chronic Cough (CC), Refractory Chronic Cough
Mechanisms of Change in Behavioral Cough Suppression Therapy for Refractory Chronic Cough
This study is testing new ways to help people who have chronic cough that has not improved with typical treatments. One approach is called behavioral cough suppression (BCS) therapy, which teaches people techniques to stop…
- Conditions
- Chronic Cough (CC), Refractory Chronic Cough, Unexplained Chronic Cough
- Trial name
- CoughLESS (NCT06960759)
- Testing
- BCS+inactive, BCS+active
- Where
- 3 sites in United States
- Volunteers
- 135 people
- Sponsor
- University of Montana