Clinical trials: Behavior and Behavior Mechanisms
Stress, Learning, Spatial
Influence of Stress on Encoding and Prediction
The purpose of this study is to investigate the neural mechanisms by which acute stress influences statistical learning and episodic encoding.
- Trial name
- NCT05920161
- Testing
- Socially Evaluated Cold Pressor Test, Control
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Yale University
Adiposity, Metabolic Complication
Insight Into New Brown Adipose Tissue Activators.
The general purpose of the study was to provide new information about the role of macronutrients intake, metabolomics, proteomics and microRNA on BAT activation.
- Conditions
- Adiposity, Metabolic Complication, Metabolic Disturbance, Healthy
- Trial name
- NCT04787952
- Testing
- cold expossure
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Cachexia, Neoplasms
Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms
Muscle mass loss is a common adverse effect of cancer. Muscle mass loss occurs with or without reduction in body weight. Cancer cachexia (CC) is the involuntary loss of body weight of >5% within 6 months and it occurs in 50-80%…
- Conditions
- Cachexia, Neoplasms, Exercise, Metabolism
- Trial name
- PANACEA (NCT05307367)
- Testing
- Exercise training
- Where
- Denmark
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Influenza Vaccination, Behavior And Behavior Mechanism
Strengthening Intentions
participants are randomized to a study arm that measures intention to perform a health related behavior and follows up to measure behavior
- Trial name
- NCT07222774
- Testing
- Experimental
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Physical Inactivity, Psychological
MOVEOUT: A Cluster RCT Investigating Education Outside the Classroom
The purpose of this study is to investigate the efficacy of an education outside the classroom (EOtC) intervention on adolescents' physical activity, school motivation, academic achievement, and wellbeing.
- Conditions
- Physical Inactivity, Psychological, Motivation, School Burnout
- Trial name
- MOVEOUT (NCT05237674)
- Testing
- The TEACHOUT intervention
- Where
- 3 sites in Denmark
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Eating Behavior
Mother-Baby Study - Caloric Compensation Index (COMPX)
The study will test a model of biobehavioral mechanisms involved in the development of a system of emotion, attachment, and nutritive intake in the mother-infant dyad and the association of this system with maternal feeding…
- Trial name
- NCT06072664
- Testing
- Caloric Compensation Index (COMPX)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Behavior and Behavior Mechanisms, Body Representation
Visuo-Tactile Integration and Body Ownership in the Human Brain
The present project exploits brain imaging and neuroscience robotics to investigate the role of quantifiable visual input on the relationship between visuo-tactile integration and body ownership (the feeling that "this" body…
- Trial name
- NCT05164991
- Testing
- Visuo-tactile stimulations of the right hand
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Depression
Inflammation-Induced Depressed Mood: The Role of Social Neurocognitive Mechanisms
Depressive disorders occur at a high rate in patients with inflammatory disorders, with a point prevalence of 15-29%, which is two to three times greater than that observed in the general population.
- Trial name
- NCT01671150
- Testing
- endotoxin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obsessive Compulsive Disorder
Neural Mechanisms of CBT Response in Hoarding Disorder
The purpose of this research is to measure changes in brain activity with functional magnetic resonance imaging (fMRI) before and after cognitive-behavioral therapy for compulsive hoarding.
- Trial name
- NCT01956344
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Parkinson's Disease (PD), GBA1 Parkinson Disease
Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging
The project aims to investigate how abnormal accumulation of alpha synuclein and its interaction with tau influence brain function across the Parkinson's disease (PD) spectrum, with particular focus on individuals carrying GBA1…
- Conditions
- Parkinson's Disease (PD), GBA1 Parkinson Disease, REM Sleep Behavior Disorder (iRBD)
- Trial name
- SYNchronPD (NCT07474779)
- Testing
- brain imaging, blood draw, Skin biopsy
- Where
- 2 sites in Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pavia
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Intervention Development
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT04077138
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
Physical Inactivity, Overweight or Obesity
eMOTION Formative Study
The eMOTION Study is a two-part ORBIT model phase 1 trial. The first part, called the Formative Study, will assess acceptability and feasibility of a novel physical activity intervention in adults at increased risk for cancer due…
- Conditions
- Physical Inactivity, Overweight or Obesity, Cancer
- Trial name
- NCT06125964
- Testing
- Intensity-Based Goals, Affect-Based Goals, TYPE/CONTEXT Enhancement
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Depression, Involutional
Function of Catecholamines in the Brain During Depression
This study will explore brain function related to depressive symptoms and will examine DNA for genes that may be involved in depressive disorders, particularly genes that regulate synthesis and metabolism of the brain…
- Trial name
- NCT00082030
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Exercise, Energy
The Comparison of Energy in Take and Body Weight EXERCISE
This study will compare the effect of two doses of exercise on energy intake and body weight. The comparison will be between three groups; two exercise groups and a control group.
- Conditions
- Exercise, Energy, Body Weight
- Trial name
- E-MECHANIC (NCT01264406)
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Cardiovascular Disease, Aging
Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function
Healthy but sedentary aging leads to increased morbidity and mortality of cardiovascular disease. This is partly due to the accumulation of Advanced Glycation Endproducts (AGEs) and the stiffening of the myocardium and arteries.
- Conditions
- Cardiovascular Disease, Aging, Endothelial Dysfunction, Physical Activity
- Trial name
- NCT01417663
- Testing
- Alt-711, Physical exercise training
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Overweight
Identifying the Effect and Working Mechanisms of MyPlan 2.0 in Older Adults
The aim of this study is to investigate whether and how 'MyPlan 2.0' helps older adults to be more physically active or less sedentary. Two groups will be created, an intervention group and a waiting-list control group.
- Trial name
- NCT03799146
- Testing
- MyPlan 2.0, Waiting List
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Ghent
Appetitive Behavior, Obesity
Neural Mechanisms for Appetitive Responses to High Reward Foods
This study is aimed at understanding neuroendocrine responses to different types of sugars and how this influences feeding behavior among lean, overweight, and obese individuals.
- Trial name
- NCT02945475
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity
Adipogenic Capacity as a Mediator of Weight Gain
To demonstrate differences in response of subjects with a high, low or medium predisposition for weight regain after weight reduction in terms of: body composition; energy expenditure; physical activity; and adipogenic capacity.
- Trial name
- NCT01015508
- Testing
- Very Low Energy Diet (VLED), Weight maintenance
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Physical Activity
Investigations of the Effects and Associated Neural Mechanisms of Different Exercise in People With Metabolic Syndrome
Metabolic syndrome (MetS) is a risk for many chronic diseases of middle-aged and older adults. Hence, prevention and treatment of MetS is a crucial global health issue.
- Trial name
- NCT05672940
- Testing
- Aerobic plus resistance training, Stretching plus breathing training
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Attention Deficit Disorder, Hyperactivity Disorder
Neural Mechanisms of Attention Lapses in Adult ADHD
ADHD is a common disorder, leading to a significant disability that often persists in adulthood. ADHD is characterized by attentional disturbances that are difficult to asses with standard neuropsychological tests.
- Trial name
- AttLapse-TDA (NCT03948607)
- Testing
- Electroencephalography during sustained attention task.
- Where
- France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France