Clinical trials: Behavior and Behavior Mechanisms
Tinnitus, Hearing Loss
Investigating Disinhibitory Brain Mechanism in Tinnitus and Hearing Loss
Tinnitus, the perception of sound in the absence of an external acoustic stimulus. Tinnitus is often perceived inside the head rather than the ear and is a common condition with a prevalence estimated between 10 and 15% in…
- Trial name
- IGNITE (NCT04862572)
- Testing
- MRI scanning
- Where
- 3 sites in United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Transcutaneous Electric Nerve Stimulation, Gambling
Brain Mechanism and Intervention of Executive-control Dysfunction Among Gambling Disorder
The investigators assume that transcranial Alternating Current Stimulation (tACS) could improve gambling disorder patients' executive-control function by adjusting the synchronization patterns and enhancing the functional…
- Trial name
- NCT06195995
- Testing
- Transcranial alternating current stimulation-true stimulus
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Mental Health Center
Stress, Psychological Stress
Neural Correlates of Stress Reduction
This study will identify neural mechanisms associated with changes in emotion regulation following participation in stress reduction programs.
- Conditions
- Stress, Psychological Stress, Life Stress, Emotional Stress
- Trial name
- NCT01488422
- Testing
- Stress Reduction
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Attention Deficit-Hyperactivity Disorder
Biomarker Research in ADHD: the Impact of Nutrition
Attention deficit hyperactivity disorder (ADHD) is the most common childhood behavioural disorder, causing significant impediment to a child's development. The exact aetiology of ADHD is still unknown.
- Trial name
- BRAIN (NCT03440346)
- Testing
- Few-foods diet
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Wageningen University
Cardiometabolic Syndrome, Physical Inactivity
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8…
- Conditions
- Cardiometabolic Syndrome, Physical Inactivity, Hypertension, Type 2 Diabetes
- Trial name
- NCT06055036
- Testing
- Black Impact Intervention
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Ohio State University
Depression
Study on Allopregnanolone and Depression in Women Across the Menopause Transition
This study aims to identify how enhanced allopregnanolone activity (via pregnenolone) affects behavior and neurobiology that may underlie perimenopausal depression.
- Trial name
- SADIE-P (NCT06238700)
- Testing
- pregnenolone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Beth Israel Deaconess Medical Center
Smoking, Smoking Cessation
Couples Dynamics and Smoking Cessation
This study is about investigating smoking and attempts to quit smoking in couples. Participation will help determine better treatment efforts for couples who want to quit smoking.
- Conditions
- Smoking, Smoking Cessation, Cessation, Smoking, Smoking Behaviors
- Trial name
- SCOR (NCT03885336)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of Southern California
Cyberbullying
Peer Group Training vs Direct Instruction to Reduce Cyberbullying Among High School Boys"
This study aims to explore ways to reduce cyberbullying among male high school students in Tehran by comparing two types of training: direct instruction from a psychologist and peer-led training.
- Trial name
- CyberPeer (NCT07204730)
- Testing
- Direct Social Skills Training, Peer-Led Social Skills Training, Control No Training
- Where
- Iran
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Ahvaz Jundishapur University of Medical Sciences
Major Depressive Disorder, Bipolar Disorder
Brain Mechanisms of Human Motivation
This study aims to investigate reward learning across the mood disorder spectrum and to investigate the predictive validity of reward learning for subsequent symptom severity.
- Trial name
- NCT01976975
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Behavior and Behavior Mechanisms, Body Representation
Visuo-Tactile Integration and Body Ownership in the Human Brain
The present project exploits brain imaging and neuroscience robotics to investigate the role of quantifiable visual input on the relationship between visuo-tactile integration and body ownership (the feeling that "this" body…
- Trial name
- NCT05164991
- Testing
- Visuo-tactile stimulations of the right hand
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
PTSD, Depression
Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care
The most common reasons Veterans seek VA addiction and mental health care is for help with opioid and alcohol misuse, depression and PTSD.
- Conditions
- PTSD, Depression, Alcohol Use Disorder, Opioid Use Disorder
- Trial name
- NCT04356274
- Testing
- Participatory System Dynamics (PSD), Audit and Feedback (AF)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Sarcopenic Obesity, Muscle Weakness
Mechanisms of Age-Related Muscle Loss
Two independent, but interrelated conditions that have a growing impact on healthy life expectancy and health care costs in developed nations are the age related loss of muscle mass (sarcopenia) and obesity.
- Conditions
- Sarcopenic Obesity, Muscle Weakness, Protein Metabolism Disorder, Physical Activity
- Trial name
- NCT03113279
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Depression, Anxiety
Mechanisms of Anxiety and Depression Study
Eligible participants will come in for three separate visits in which they will be interviewed, perform a variety of tasks, and undergo a non-invasive MRI scan.
- Trial name
- NCT03135756
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Palo Alto University
Depression
Reconsolidation-Based Intervention for Traumatic Memories
The goal of this clinical trial is to test the effect and underlying mechanism of reconsolidation-based cognitive reappraisal for traumatic memories in patients with major depression disorder.
- Trial name
- NCT06143800
- Testing
- reactivation, cognitive reappraisal intervention
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Shenzhen Kangning Hospital
Lung Transplant, End Stage Lung Disease
GRAfT 2.0. A Multimodal Prospective Approach to Define the Mechanisms and Clinical Features of Acute and Chronic Rejection in Lung Transplantation
Background: Lung transplants can save lives, but the procedure has risks. Some people develop donor-specific antibodies (DSA) after the procedure-that is, their bodies create proteins that treat the new lungs as foreign and mount…
- Conditions
- Lung Transplant, End Stage Lung Disease, Rejection
- Trial name
- NCT07516379
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Internet Gaming Disorder
The Behavioral and Brain Mechanism of IGD
This project aims to investigate whether anodal tDCS of dlPFC enhances cognitive regulation over craving an emotions.
- Trial name
- NCT02550405
- Testing
- Craving behavioral intervention
- Where
- China
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Beijing Normal University
Behavior Change, Dietary Behaviour
Novel Personalised Nutrition Intervention With Tailored Behavioural Support
The aim of this study is to test the efficacy of a novel personalised nutrition intervention with tailored behavioural support compared to a control personalised nutrition intervention for improving adherence to sustainable and…
- Conditions
- Behavior Change, Dietary Behaviour, Personalised Nutrition, Sustainable Healthy Diet
- Trial name
- P-NUTS (NCT07417254)
- Testing
- Personalised sustainable and healthy dietary recommendations with standardised and tailored behavioural support., Personalised sustainable and healthy dietary recommendations with standardised behavioural support.
- Where
- Ireland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Criminal Behavior, Violence
A Randomized Controlled Trial of ACT-P Versus T4C for Community Reentry
The purpose of the proposed study is to determine the efficacy of Acceptance and Commitment Therapy for prisons (ACT-P) and Thinking for a Change (T4C) as reentry programs in a randomized controlled trial (RCT).
- Trial name
- NCT05109689
- Testing
- ACT-P, T4C
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Iowa State University
Chronic Low Back Pain (CLBP)
Neuroimmune Responses to Exercise in Chronic Back Pain
The goal of this mechanistic clinical trial is to learn how physical exercise affects the body and brain in people with chronic low back pain.
- Trial name
- eCLBP (NCT07497425)
- Testing
- Physical Exercise
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- McGill University
HIV, Depression
Stress and Pain in People Living With HIV
This is a basic human experimental study utilizing 4 groups of individuals with and without HIV and complex morbidities of cannabis use disorder and major depression who will participate in 2 sessions of the Yale Pain Stress Task…
- Conditions
- HIV, Depression, Cannabis Use Disorder, Stress
- Trial name
- HIV Stress (NCT06784908)
- Testing
- Yale Pain Stress Task (YPST)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University