Clinical trials: Behavior and Behavior Mechanisms
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Neural Mechanisms of Sensory Processing Anomalies
To assess sensory processing anomalies in neurotypical children, children with autism spectrum disorder, and attention-deficit hyperactivity disorder, particularly within the vibrotactile and auditory sensory modalities.
- Conditions
- Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Sensory Processing Disorder
- Trial name
- NCT06234033
- Testing
- Discrimination Acuity test, Transiently Evoked Otoacoustic Emission, Questionnaires
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Aalborg University
Mindfulness, DNA Methylation
Effects of Mindfulness-based Intervention on Epigenetic Mechanisms, Cognition Function, Stress Response, and Well-being
The purpose of this study is to assess the effect of a mindfulness-based intervention on DNAmethylation, cognitive functions, stress response, and well-being in healthy female adults.
- Conditions
- Mindfulness, DNA Methylation, Learning and Memory, Stress
- Trial name
- NCT05085847
- Testing
- Mindfulness meditation training, Active control
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Child Behavior Disorders, Implementation Science
Pre-Implementation Enhancement Strategy To Improve Teachers' Intention to Implement Evidence-Based Practices
Background: As the most common setting where youth access behavioral health services, the education sector frequently employs training and follow-up consultation as cornerstone implementation strategies to promote the uptake and…
- Conditions
- Child Behavior Disorders, Implementation Science, Adolescent Problem Behavior at School, Healthcare Providers
- Trial name
- SC-PIES (NCT05240222)
- Testing
- Pre-implementation enhancement strategies (SC-PIES)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Anxiety Disorders, Depression
Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)
The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms.
- Conditions
- Anxiety Disorders, Depression, Post Traumatic Stress Disorder
- Trial name
- NCT06273527
- Testing
- COGENT
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of California, San Diego
Obesity, Depression
Engaging Self-regulation Targets to Improve Mood and Weight and Understand Mechanism in Depressed and Obese Adults
Multimorbidity (i.e., the coexistence of 2 or more chronic conditions in an individual) is increasingly recognized as a pressing public health problem.
- Trial name
- NCT03841682
- Testing
- I-CARE2
- Where
- 2 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Self-Control
Stress & Self-Control Costs
Self-control failures are a universal challenge for healthy and clinical populations. Recent work suggests these failures may arise from excessive cognitive costs associated with exercising self-control, yet the mechanisms…
- Trial name
- NCT05795179
- Testing
- Cold-Pressor Task (CPT), Trier Social Stress Test (TSST), Modified Non-Stress CPT
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Appetitive Behavior, Obesity
Neural Mechanisms for Appetitive Responses to High Reward Foods
This study is aimed at understanding neuroendocrine responses to different types of sugars and how this influences feeding behavior among lean, overweight, and obese individuals.
- Trial name
- NCT02945475
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Rumination, Worry
An Idiographic Examination of Treatment Mechanisms in Emotion Regulation Therapy
This study is an open trial designed to examine individual changes that occur before, during, and after 12 sessions of Emotion Regulation Therapy (ERT) delivered via telehealth for individuals in New York State who are…
- Conditions
- Rumination, Worry, Self-Criticism, Anxiety
- Trial name
- NCT05590741
- Testing
- Emotion Regulation Therapy via Telehealth
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Teachers College, Columbia University
Obesity, Exercise Reinforcement
Exercise and Weight Control
The objective of this project is to determine the biological, neurobehavioral, and behavioral compensatory responses to exercise training-induced energy deficits in overweight to obese men and women.
- Trial name
- NCT03413826
- Testing
- Exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Cognitive Impairment, Bipolar Disorder
Effects of Altitude-like Cognition Training on Neuroplasticity and Cognitive Functions
The goal of this clinical trial is to investigate the effects of a three-week altitude-like cognition training intervention in healthy individuals (substudy 1) and symptomatically stable patients with mood disorders (depression…
- Conditions
- Cognitive Impairment, Bipolar Disorder, Depression
- Trial name
- ALTIBRAIN (NCT06121206)
- Testing
- Altitude-like hypoxia (12% O2), Normoxia (20% O2), Cognitive training
- Where
- Denmark
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Traumatic Brain Injury, Attention Deficit Disorder
Treatment of Traumatic Brain Injury (TBI)-Related Attention Deficits
The purpose of this research study is to evaluate whether Vyvanse, a psychostimulant, can help with attention deficits due to traumatic brain injury (TBI).
- Trial name
- NCT01000064
- Testing
- Vyvanse, fMRI
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Vanderbilt University
Behavior Problem, Social Skills
Inclusive Positive Behaviour Supports
Background: While positive school climate is important for students' well-being and mental health, school personnel may experience challenges in creating a nurturing school climate.
- Trial name
- IBIS (NCT06270914)
- Testing
- Inclusive Positive Behavior Interventions and Supports
- Where
- Sweden
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Smoking
Neuroimaging Reward, Behavioral Treatment, and Smoking Cessation
The goal of this study is to evaluate the effects of a smoking cessation intervention combining behavioral treatment with low nicotine cigarettes on neuroimaging measures of reward function and smoking cessation outcomes.
- Trial name
- NCT02927847
- Testing
- Nicotine Patch, SPECTRUM Nicotine Research Cigarettes (.03 mg), Behavioral Activation
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Maggie M Sweitzer, PhD
Sedentary Lifestyle, Behavioral Intervention
Effects of Baduanjin Exercise on Improving Health in Sedentary Young and Middle-Aged Adults
The goal of this clinical trial is to learn if a 12-week Baduanjin exercise program can improve health in sedentary young and middle-aged adults. The main questions it aims to answer are: 1.
- Trial name
- NCT07482995
- Testing
- Baduanjin exercise, General Health Education
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Obesity, Weight Loss
Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity
Obesity is a common chronic disease linked with increased risk for other illnesses and earlier death. Our team and others have shown that many bodily and psychological changes occur when individuals are on calorie-restricted…
- Conditions
- Obesity, Weight Loss, Weight Management, Dietary Intervention
- Trial name
- NCT06809166
- Testing
- Contrave, Diet Program
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- The Royal's Institute of Mental Health Research
Psychological Disorder, Anxiety Disorders
Examining Change Mechanisms in Psychotherapy
This research project seeks to acquire a deeper understanding of the complex influences of common factors and specific ingredients in psychotherapy.
- Conditions
- Psychological Disorder, Anxiety Disorders, Depression, Eating Disorder
- Trial name
- CAMP (NCT03503981)
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 520 people
- Sponsor
- Modum Bad
Depression, Involutional
Function of Catecholamines in the Brain During Depression
This study will explore brain function related to depressive symptoms and will examine DNA for genes that may be involved in depressive disorders, particularly genes that regulate synthesis and metabolism of the brain…
- Trial name
- NCT00082030
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Adolescent Depression
Adolescent Mood During Puberty and Testosterone
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention…
- Trial name
- AMPT (NCT06072677)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Gambling Disorder
Effects of Transcranial Temporal Interference Stimulation on Risky Decision-making and Impulse Control in Gambling Disorder
The purpose of this research is to investigate the effect of transcranial temporal interference stimulation (tTIS) targeting the dorsal anterior cingulate cortex in patients with gambling disorder.
- Trial name
- NCT06467422
- Testing
- tTIS on dACC, theta frequency (5 Hz), tTIS on dACC, High frequency
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Cardio-cerebral Vascular Events, Arteriovenous Fistula Dysfunction
Impact and Mechanism of Depression on Cardio-cerebral Vascular Events and Arteriovenous Fistula Dysfunction in MHD Patients
Depression is a common psychiatric disorder in patients on maintenance hemodialysis (MHD). It may contribute to poor prognosis in a number of ways, including its effect on platelet function.
- Trial name
- NCT06070805
- Testing
- depression
- Where
- China
- Volunteers
- 286 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University