Clinical trials: Behavioral Addiction
Evaluation of Abuse Potential of Sativex
Abuse Potential of Sativex
This crossover study with six treatment sessions is to evaluate the abuse potential of three doses of Sativex as compared to Marinol and placebo, in subjects with a history of recreational marijuana use.
- Trial name
- NCT01323569
- Testing
- Sativex, Marinol
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Jazz Pharmaceuticals
Addiction
Prevalence of New Psychoactive Substances Use
According to the United Nations Office on Drugs and Crime [UNODC] World Drug Report, the annual prevalence of drug use seemed to be stable for the past few years.
- Trial name
- NCT03695419
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Nicotine Use Disorder, Tobacco Use Disorder
Evaluation of the Addictive Potential of E-Cigarettes
This study will examine the subject matter from a neurobiological and a neuropsychological vantage point to ascertain whether the e-cigarette is potentially as addictive as the traditional tobacco cigarette.
- Trial name
- EVAPE (NCT04772014)
- Where
- Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Internet Gaming Disorder, Social Media Addiction
Chatbot Intervention to Reduce Common Digital Addictions, Sedentary Behaviors and Mental Distress Among Adolescents
The goal of the study is to investigate the efficacy of a secondary low-intensity stage of change (SoC) and motivational interviewing (MI)-based Chatbot-assisted intervention in reducing digital addictions in adolescents with…
- Trial name
- NCT06821373
- Testing
- Chatbot, Control
- Where
- Hong Kong
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mental Health, Addictions
Better Access to and Integration of Mental Health and Addiction Services Through Navigation: A Mixed-Methods Adaptive Pragmatic Clinical Trial
The Family Navigation Project (FNP), a youth and family mental health and addictions (MHA) navigation service that currently operates in the Greater Toronto Area (GTA), is expanding to northern Ontario by setting up a new site in…
- Conditions
- Mental Health, Addictions, Patient Navigation, Health Services
- Trial name
- BEAM (NCT07707492)
- Testing
- Family Navigation Project
- Where
- 2 sites in Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Substance Dependence
An Open Label Positron Emission Tomography (PET) Study of GSK618334 in Healthy Male Subjects Using 11C-PHNO as PET Ligand
The purpose of this study is to investigate the relationship between the plasma concentrations of the study drug and the amount of the study drug bound to the D3 receptors of the brain after dosing of a new compound GSK618334.
- Trial name
- NCT00814957
- Testing
- GSK618334
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smartphone Addiction
The Effects of Smartphone Addiction on Pinch Strength, Muscle Stiffness, and Hand/Wrist Function in Young Adults
Smartphones have become an indispensable part of daily life, and their increasing use has raised concerns about various health effects, including musculoskeletal symptoms.
- Trial name
- NCT06843863
- Testing
- No intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Smoking Cessation, Nicotine Addiction
Nicotine Receptor Levels and Smoking Cessation
The investigators propose to use positron emission tomography (PET) imaging to determine whether nicotinic receptor availability at pretreatment predicts smoking cessation success.
- Trial name
- NCT01788943
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking, Tobacco
Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction
Physically healthy adult smokers may be eligible for this study. Volunteers may participate in this study if they are 18 - 65 years old.
- Trial name
- NCT03442413
- Testing
- 2-[18F]-FA PET/CT, I.V. Nicotine
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Prenatal Alcohol Exposure
Effects of Prenatal Alcohol Exposure on Emotional and Cognitive Abilities in Adults
Hypothesis: Individuals presenting with prenatal alcohol exposure (PEA) show emotional abilities deficits, and imbalance between the two systems involved in decision-making according to dual-process models, namely an…
- Trial name
- ALTEMO (NCT03793920)
- Testing
- Facial Emotion Test
- Where
- 2 sites in France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Smoking (Tobacco) Addiction
Short-bout Handgrip Exercise Intervention
This study aims to examine the effect of practicing short-bout handgrip and isometric exercises on nicotine craving, smoking urges and withdrawal symptoms in adult smokers undergoing acute tobacco abstinence.
- Trial name
- NCT04059497
- Testing
- Exercise condition, Healthy diet condition
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Addiction, Psychiatric Disorder
Validating Promoted Spiritual Experience
This pilot study of 16 patients will demonstrate a specific psychologically focused intervention to affect a spiritual aspect of psychological health and will measure (1) its effects on general distress, depression, anxiety and…
- Trial name
- NCT05485181
- Testing
- Spiritual Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Opioid Dependence, Opioid Use Disorder (OUD)
VK4-116 Phase I Study With Food-Effect
This first-in-human, randomized, double-blind, placebo-controlled, single ascending dose (SAD), phase I study is designed to assess the safety, tolerability and pharmacokinetics of VK4-116 in healthy volunteers in fasted and fed…
- Trial name
- NCT06808932
- Testing
- VK4-116
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Substance Use Disorders, Adolescent Behavior
Addiction in Adolescence - Pathomechanisms and Treatment Evaluation
This study aims to investigate the sociodemographic background as well as psychiatric comorbidities of adolescent substance users with substance use disorders.
- Trial name
- MATRIX-A (NCT03444974)
- Testing
- adapted treatment according to the MATRIX-A therapy
- Where
- Germany
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Level of Digital Game Addiction, Level of Cyberbullying
Digital Game Addiction and Cyberbullying in Adolescents
With the widespread use of technology and internet, digital game addiction and cyberbullying behaviors have increased among adolescents. Effective interventions are needed to prevent these behaviors.
- Trial name
- NCT06241989
- Testing
- health education supported by motivational interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Opioid-use Disorder
Intervention to Expand Opioid Use Disorder Treatment Pharmacotherapy Prescribers
This is a cluster-randomized controlled trial designed to increase the availability of buprenorphine and extended-release naltrexone treatment capacity for opioid use disorder (OUD).
- Trial name
- NCT02926482
- Testing
- Prescriber Recruitment Bundle (PRB)
- Where
- 3 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Smoking, Smoking Cessation
Treating Caregivers Who Smoke at AFCH
The purpose of this research study is to 1) see if a smoking cessation program is something that caregivers will use while their child is hospitalized, 2) see if caregivers think this program is something we should institute…
- Trial name
- NCT06051474
- Testing
- Nicotine Replacement Product
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Alcoholism
To Evaluate the Influence of the A118G Polymorphism in the mu Opioid Receptor Gene (OPRM1) on Effects of GSK1521498 and Naltrexone on Physiological and Behavioural Markers of Brain Function in Healthy Social Drinkers
A total of at least 48 healthy subjects with a history of social drinking will be recruited into this single-centre, randomized, double-blind, cross-over study.
- Trial name
- NCT01738867
- Testing
- GSK1521498, Naltrexone (NTX)
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Internet Addiction Disorder
Cessation on Internet Addiction in College Students
This study aimed to explore the intervention effect of Tai Chi exercise on internet addiction in college students and its maintenance effect after cessation, providing a scientific basis for the application of Tai Chi in internet…
- Trial name
- IAD (NCT06921096)
- Testing
- Tai Chi
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Chengdu Sport University
Cannabis Dependence
Neural Indices Associated With Relapse in Cannabis Dependence
The aim of this fMRI study is to investigate neural indices of relapse in cannabis dependence. The development and maintenance of drug addictions have been associated with deficits in cognitive control, craving and impaired…
- Trial name
- NCT02801422
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China