Clinical trials: Behavioral Difficulties, open to volunteers
Language Delay, Language Development
Combined Oral Motor Stimulation and Language on Preterm Infant Feeding
This is a randomized controlled trial to study an oromotor stimulation in combination with a reading curriculum in the NICU among preterm infants using oral muscle exercises, Language Environment Analysis (LENA) recordings…
- Conditions
- Language Delay, Language Development, Feeding; Difficult, Newborn, Mother-Infant Interaction
- Trial name
- NCT05861531
- Testing
- Oromotor stimulation, Reading curriculum, LENA recording
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Vision and Hearing Loss, Vision Impairment
SENSE-Brain Health Pro for Older Adults With Sensory Loss
The goal of this study is to learn about the outcomes, usability, and accessibility of the online Brain Health Pro program for older adults with hearing difficulties, vision difficulties, or both.
- Conditions
- Vision and Hearing Loss, Vision Impairment, Hearing Impairment, Vision Difficulty
- Trial name
- SENSE-BHPro (NCT07856888)
- Testing
- Brain Health Pro
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Université de Montréal
Adherence, Medication, HIV Infections
Optimizing Care for Challenging People Living With HIV
Conduct an intervention combining social and behavioral health models with digital health technologies to improve their adherence to their medication schedules.
- Conditions
- Adherence, Medication, HIV Infections, Social Media
- Trial name
- NCT06183723
- Testing
- Combination of social-behavior model and eHealth
- Where
- Taiwan
- Volunteers
- 210 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Infant Regulatory Problems, Regulatory Problems in Infancy
Developing and Testing a Preventive Primary Care Parenting Intervention to Strengthen Parent-Infant Co-Regulation in Families Experiencing Early Regulatory Difficulties
The goal of this randomized controlled trial is to evaluate the effectiveness of a structured parenting support program for families with young infants experiencing early regulatory difficulties.
- Conditions
- Infant Regulatory Problems, Regulatory Problems in Infancy, Parental Stress, Parental Self-efficacy
- Trial name
- NCT07541716
- Testing
- Structured early parenting support program, called "Eat, sleep, cry - repeat"
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universiteit Antwerpen
Attention Deficit Hyperactivity Disorder, Attention Difficulties
Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation
Inattentiveness and impulsivity in healthy adults and individuals with attention deficit hyperactivity disorder (ADHD) diminish these individuals' quality of life.
- Conditions
- Attention Deficit Hyperactivity Disorder, Attention Difficulties, Attention Deficit, Cognitive Deficit
- Trial name
- NCT05802680
- Testing
- Transcranial photobiomodulation
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Francisco Gonzalez-Lima, PhD
Depression
Changing Tactics? Optimizing ECT in Difficult-to-treat Depression
The goal of this randomized controlled trial is to address which treatment strategy (continue right unilateral (RUL) ECT or switch to bitemporal (BT) ECT speeds up recovery and has the least impact on memory function, in case of…
- Trial name
- ChaT (NCT05923801)
- Testing
- switch to BT electrode position, continue with RUL electrode position
- Where
- Belgium
- Volunteers
- 196 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Major Depressive Disorder (MDD), Treatment Resistant Depression (TRD)
Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression
The goal of this study is to collect feasibility data on combining structured exercise aimed to improve physical fitness, and intermittent TBS (iTBS) in treating individuals diagnosed with difficult-to-treat depression who are…
- Trial name
- NCT06773949
- Testing
- Theta burst stimulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Royal Ottawa Mental Health Centre
ADHD, Dyslexia
Dual Executive Function Training Package
Executive function (EF) refers to the cognitive processes that enable goal-directed regulation of thoughts, emotions, and behaviours.
- Conditions
- ADHD, Dyslexia, Autism
- Trial name
- NCT07262853
- Testing
- Executive Function Training
- Where
- Hong Kong
- Volunteers
- 288 people
- Sponsor
- Education University of Hong Kong
Reintegration Difficulties, Health
National Sponsorship Program for Transitioning Service Members
Background: The United States is undergoing a suicide epidemic for its youngest Veterans (18-to-34-years-old) as their suicide rate has almost doubled since 2001.
- Conditions
- Reintegration Difficulties, Health, Suicidal Ideation and Behaviors, Connectedness
- Trial name
- NCT05224440
- Testing
- Veteran Sponsorship Initiative
- Where
- 2 sites in United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression - Major Depressive Disorder, Depression Bipolar
Mental Health Mission Mood Disorder Cohort Study
The current study aims to understand why some people with depression respond to treatment and others do not, using markers of clinical symptoms, both clinician reported outcome measures and patient reported outcome measures…
- Conditions
- Depression - Major Depressive Disorder, Depression Bipolar, Treatment Resistant Depression
- Trial name
- NCT07189689
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- University of Oxford
Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms
Trauma-Focused Cognitive Behavioral Therapy in Unaccompanied Refugee Minors With PTSD in Greece: An RCT
This single-blinded, multicentered, randomized controlled trial aims to evaluate the effectiveness of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) compared to Treatment-as-Usual (TAU) in reducing post-traumatic stress…
- Conditions
- Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms, Anxiety Symptoms, Somatic Symptoms
- Trial name
- TF-CBT (NCT06975280)
- Testing
- Trauma - Focused Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Theodora Anastasiou
Difficulties of Emotion Regulation, Self-harm Behavior
DBT Skill Training for Autistic Adults With Difficulties in Emotion Regulation.
One in 44 has autism, 70% of them have additional mental health challenges. Currently, this patient population does not have access to effective treatment within specialist healthcare services and has struggled to benefit from…
- Conditions
- Difficulties of Emotion Regulation, Self-harm Behavior, Autism Spectrum Disorder
- Trial name
- NCT07021274
- Testing
- DBT skills training adjusted to autistic needs
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Helse Møre og Romsdal HF
Breastfeeding
Get the Benefits From the Start. Improving Breastfeeding
Breastfeeding is beneficial for the physical and mental health of mothers and infants alike. Most new mothers in Denmark intend to breastfeed, however, a substantial proportion do not succeed to breastfeed as intended.
- Trial name
- NCT05871853
- Testing
- Improved breastfeeding support
- Where
- Denmark
- Volunteers
- 1,600 people
- Sponsor
- Slagelse Hospital
Mental Health
Evaluating a Mental Health Digital Intervention for Dads
Approximately one in 10 fathers experience mental health difficulties during their partner's pregnancy and/or the postpartum period.
- Trial name
- HealthyDads (NCT06872411)
- Testing
- HealthyDads Digital Intervention
- Volunteers
- 100 people
- Sponsor
- McGill University
Cancer-related Cognitive Impairment, Cancer-related Cognitive Dysfunction
CanCOG®: Pilot Trial of Cognitive Rehabilitation for Cancer Survivors
Cancer-related cognitive impairment (CRCI) affects a large proportion of non-central nervous system cancer survivors and can negatively impact cognitive functioning and daily life.
- Conditions
- Cancer-related Cognitive Impairment, Cancer-related Cognitive Dysfunction, Cancer-related Cognitive Difficulties, Depression and Anxiety Symptoms
- Trial name
- CanCOG® (NCT07755839)
- Testing
- CanCOG® - Cogntive Rehabilitation in Cancer
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Aveiro University
Premature Birth, Breastfeeding, Exclusive
taVNS-Paired Breastfeeding to Improve Breastfeeding at Discharge
Investigators aim to improve the skills of premature or sick term infants in breastfeeding by boosting motor learning with transcutaneous vagus nerve stimulation.
- Conditions
- Premature Birth, Breastfeeding, Exclusive, Feeding; Difficult, Newborn
- Trial name
- NCT06417385
- Testing
- taVNS soterix device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Major Depression Moderate, Major Depression Severe
EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT
This study aims to investigate the neurophysiological and inflammatory changes associated with electroconvulsive therapy (ECT) in older age patients diagnosed with Major Depressive Episode, Major Depression, and Bipolar Disorder…
- Conditions
- Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression With Panic Attacks
- Trial name
- NCT07740694
- Testing
- Electroconvulsive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
ADHD - Attention Deficit Disorder With Hyperactivity, Attention Concentration Difficulty
Danish Access to Support and Help (DASH): Increasing Access to an Evidence-based Intervention for Children With ADHD and Their Parents
The aim of this study is to devise implementation strategies for the New Forest Parenting Programme (NFPP) to support a community implementation model (NFPP-CIM) and test its feasibility and acceptability for parents and…
- Trial name
- DASH (NCT07339696)
- Testing
- New Forest Parenting Programme
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Reintegration Difficulties, Suicidal Ideation and Behaviors
Expanding Veteran Sponsorship Initiative+ to Support High-Risk Transitioning Servicemembers and Veterans: A Precision Medicine Approach
Background Young Veterans in the U.S. face a heightened risk of suicide, particularly during the first year after leaving military service-a period often referred to as the "deadly gap." Suicide rates among Veterans aged 18 to 34…
- Conditions
- Reintegration Difficulties, Suicidal Ideation and Behaviors, Health, Connectedness
- Trial name
- NCT07356492
- Testing
- Onward Ops- receive peer sponsor and community support, VA stepped care services
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Parenting Intervention, Anger
Digital Behavioral Parenting Programs With and Without Added Emotion Regulation Strategies to Manage Anger in Parenting
This pilot randomized controlled trial evaluates the feasibility, acceptability, and preliminary effects of two digital parenting interventions for parents experiencing difficulties with anger in parenting.
- Conditions
- Parenting Intervention, Anger, Emotion Regulation Difficulties, Parenting Behaviour
- Trial name
- NCT07795684
- Testing
- Online Behavioral Parent Training Program, Online Behavioral Parent Training + Emotion Regulation Program
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet